|
Uncoupling (other)
Uncoupling or uncouple may refer to: * Uncoupling (neuropsychopharmacology), changes in neurochemical binding sites as a consequence of drug tolerance. * An uncoupling protein in cell biology. * An uncoupling agent in cell biology. * Un coupling (or decoupling) rail vehicles. See also * Decoupling (other) * Coupling (other) * Coupler (other) * Couple (other) * '' Uncoupled'', a Netflix romantic comedy series starring Neil Patrick Harris {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uncoupling (neuropsychopharmacology)
In neuropsychopharmacology, uncoupling, also known as decoupling, is the process of receptor- or ligand-binding sites or domains becoming separated, moving alignments and/or becoming internalised as a result of drug tolerance resulting from prolonged exposure to bioavailable psychoactive substances or toxin A toxin is a naturally occurring organic poison produced by metabolic activities of living cells or organisms. Toxins occur especially as a protein or conjugated protein. The term toxin was first used by organic chemist Ludwig Brieger (1849– ...s. References Neuropharmacology Molecular neuroscience {{psych-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uncoupling Protein
An uncoupling protein (UCP) is a mitochondrial inner membrane protein that is a regulated proton channel or transporter. An uncoupling protein is thus capable of dissipating the proton gradient generated by NADH-powered pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space. The energy lost in dissipating the proton gradient via UCPs is not used to do biochemical work. Instead, heat is generated. This is what links UCP to thermogenesis. However, not every type of UCPs are related to thermogenesis. Although UCP2 and UCP3 are closely related to UCP1, UCP2 and UCP3 do not affect thermoregulatory abilities of vertebrates. UCPs are positioned in the same membrane as the ATP synthase, which is also a proton channel. The two proteins thus work in parallel with one generating heat and the other generating ATP from ADP and inorganic phosphate, the last step in oxidative phosphorylation. Mitochondria respiration is coupled to ATP synthesis (ADP phosphorylat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uncoupling Agent
An uncoupler or uncoupling agent is a molecule that disrupts oxidative phosphorylation in prokaryotes and mitochondria or photophosphorylation in chloroplasts and cyanobacteria by dissociating the reactions of ATP synthesis from the electron transport chain. The result is that the cell or mitochondrion expends energy to generate a proton-motive force, but the proton-motive force is dissipated before the ATP synthase can recapture this energy and use it to make ATP. Uncouplers are capable of transporting protons through mitochondrial and lipid membranes. Description Classical uncouplers have five properties: # the complete release of respiratory control # the substitution of all coupled processes ( ATP synthesis, transhydrogenation, reverse electron flow, active transport of cations, etc.) by a cyclic proton transport mediated by the uncoupler # the elimination of all protonic and cationic gradients generated across the mitochondrial or prokaryotic membrane # no discriminatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Railway Coupling
A coupling (or a coupler) is a mechanism typically placed at each end of a railway vehicle that connects them together to form a train. A variety of coupler types have been developed over the course of railway history. Key issues in their design include strength, reliability, ease of making connections and operator safety. The equipment that connects the couplings to the vehicles is the draft gear or draw gear and these must absorb the stresses of coupling and train acceleration. Nomenclature Compatible and similar couplings or couplers are frequently referred to using widely differing make, brand, or regional names, or nicknames, which can make describing standard or typical designs confusing. Dimensions and ratings noted in these articles are usually of nominal or typical components and systems, though standards and practices also vary widely with railway, region, and era. Buffers and chain The basic type of coupling on railways following the British tradition is the bu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Decoupling (other)
__NOTOC__ Decoupling usually refers to the ending, removal or reverse of coupling. Decoupling may also refer to: Economics * Decoupling (advertising), the purchase of services directly from suppliers rather than via an advertising agency * Decoupling (utility regulation), the disassociation of a utility's profits from its sales * Decoupling and re-coupling in economics and organizational studies ** Decoupling (organizational studies), creating and maintaining separation between policy, implementation and/or practice * Decoupling of wages from productivity, sometimes known as the Great Decoupling * Eco-economic decoupling, economic growth without increase in environmental costs Science * Decoupling (cosmology), transition from close interactions between particles to their effective independence * Decoupling (meteorology), change in the interaction between atmospheric layers at night * Decoupling (neuropsychopharmacology), changes in neurochemical binding sites as a consequence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coupling (other)
Coupling is a connection or joint between two things. Coupling may also refer to: *Coupling (physics), when two systems are interacting with each other **Rotational–vibrational coupling, occurring when rotation frequency of an object is close to or identical to a natural internal vibration frequency **Angular momentum coupling, the combining of quantized angular momentum (e.g., the interaction between two nuclei in nuclear magnetic resonance) **Quantum coupling, when quantum states in one of the systems will cause an instantaneous change in all of the bound systems *Coupling (computer programming), the degree to which each program module relies on each one of the other modules *Coupling (electronics), the transfer of a signal from one medium or circuit block to another *Coupling (genetics), a type of genetic linkage *Coupling (piping), a short length of pipe or tube to connect two pipes or tubes together *Coupling (probability), a proof technique in probability theory *Railway co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coupler (other)
Coupler may refer to: Engineering Mechanical * Railway coupler, a mechanism for connecting rolling stock in a train device ** Janney coupler ** SA3 coupler ** Scharfenberg coupler for multiple unit passenger cars * Quick coupler, used in construction machines to allow the rapid change of buckets * Coupling, a device used to connect two shafts together at their ends for the purpose of transmitting power ** Universal coupling, a joint or coupling in a rigid rod that allows the rod to 'bend' in any direction Electronics * Acoustic coupler, for coupling electrical signals by acoustical means * Directional coupler, a passive device used in radio technology * Antenna coupler, a device connected between a radio transmitter or receiver and its antenna * Output coupler, a partially reflective mirror used in lasers Other uses * Coupler (piping), also called a (joist) short length of pipe with two female threads * Coupler, a device used on a pipe organ or harpsichord to allow a player to pl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Couple (other)
Couple or couples may refer to : Basic meaning *Couple (app), a mobile app which provides a mobile messaging service for two people *Couple (mechanics), a system of forces with a resultant moment but no resultant force *Couple (relationship), two people to whom each is the significant other of the other *Couple, a set of two of items of a type *Couple, a name for one pair of rafters *Thermocouple, a type of temperature sensor People *Fred Couples (born 1959), golfer Arts, entertainment, and media Films * ''Couples'' (film), a 2011 South Korean film * ''Couples'' (TV film), a 1994 American television film directed by Betty Thomas *'' The Aryan Couple'', a 2004 British film released in the United States as ''The Couple'' *'' A Couple'', 2022 film directed by Frederick Wiseman Literature * ''Couples'' (novel), a novel by John Updike Music *''Couple'', English market release title of 《연인》 (''Yeonin'', "lovers") Kim Yeon-woo 2004 * ''Couples'' (Pizzicato Five album), 1987 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
