Transmissible Cancers
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Transmissible Cancers
A transmissible cancer is a cancer cell or cluster of cancer cells that can be transferred between individuals without the involvement of an infectious agent, such as an oncovirus. Transmission of cancer between humans is rare. The evolution of transmissible cancer has occurred naturally in other animal species, but human cancer transmission is rare. Humans In humans, a significant fraction of Kaposi's sarcoma occurring after transplantation may be due to tumorous outgrowth of donor cells. Although Kaposi's sarcoma is caused by a virus (Kaposi's sarcoma-associated herpesvirus), in these cases, it appears likely that transmission of virus-infected tumor cells—rather than the free virus—caused tumors in the transplant recipients. In 2007, four people (3 women & 1 man) received different organ transplants (liver, both lungs and kidneys) from a 53-year-old woman who had recently died from intracranial bleeding. Before transplantation, the organ donor was deemed to have no signs of c ...
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Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ...
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Cervical Cancer
Cervical cancer is a cancer arising from the cervix. It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. Early on, typically no symptoms are seen. Later symptoms may include abnormal vaginal bleeding, pelvic pain or pain during sexual intercourse. While bleeding after sex may not be serious, it may also indicate the presence of cervical cancer. Human papillomavirus infection (HPV) causes more than 90% of cases; most women who have had HPV infections, however, do not develop cervical cancer. HPV 16 and 18 strains are responsible for nearly 50% of high grade cervical pre-cancers. Other risk factors include smoking, a weak immune system, birth control pills, starting sex at a young age, and having many sexual partners, but these are less important. Genetic factors also contribute to cervical cancer risk. Cervical cancer typically develops from precancerous changes over 10 to 20 years. About 90% of cervical cancer cas ...
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Cerastoderma Edule
The common cockle (''Cerastoderma edule'') is a species of edible saltwater clam, a marine bivalve mollusc in the family Cardiidae, the cockles. It is found in waters off Europe, from Iceland in the north, south into waters off western Africa as far south as Senegal. The ribbed oval shells can reach across and are white, yellowish or brown in colour. The common cockle is harvested commercially and eaten in much of its range. Taxonomy and naming The common cockle was one of the many invertebrate species originally described by Carl Linnaeus in the landmark 1758 10th edition of '' Systema Naturae'', where it was given its old binomial name ''Cardium edule''. The species name is derived from the Latin adjective ''ĕdūlis'' "edible". Italian naturalist Giuseppe Saverio Poli erected the genus '' Cerastoderma'' in 1795, making the common cockle the type species as ''Cerastoderma edule''. The genus name is derived from the Ancient Greek words ''keras'' "horn" and ''derma'' "skin". ...
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Mytilus Trossulus
''Mytilus trossulus'', the bay mussel or foolish mussel, is a medium-sized edible marine bivalve mollusc in the family Mytilidae. ''Mytilus trossulus'' is one of the three principal, closely related taxa in the ''Mytilus edulis'' complex of blue mussels, which collectively are widely distributed on the temperate to subarctic coasts the Northern Hemisphere, and often are dominant inhabitants on hard substrates of the intertidal and nearshore habitats. Distribution ''Mytilus trossulus'' is the main native intertidal mussel in the Northern Pacific. In North America it is found from California to Alaska, and in Asia from Hokkaido northwards. At its southern limits, it hybridizes with ''Mytilus galloprovincialis'' (the Mediterranean mussel), which has been introduced to the Pacific by human activity. In the North Atlantic, ''M. trossulus'' is found on the U.S. coast of Maine and northwards to Canada, as well as in scattered localities on North European coasts. In these regions it o ...
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National Geographic (magazine)
''National Geographic'' (formerly the ''National Geographic Magazine'', sometimes branded as NAT GEO) is a popular American monthly magazine published by National Geographic Partners. Known for its photojournalism, it is one of the most widely read magazines of all time. The magazine was founded in 1888 as a scholarly journal, nine months after the establishment of the society, but is now a popular magazine. In 1905, it began including pictures, a style for which it became well-known. Its first color photos appeared in the 1910s. During the Cold War, the magazine committed itself to present a balanced view of the physical and human geography of countries beyond the Iron Curtain. Later, the magazine became outspoken on environmental issues. Since 2019, controlling interest has been held by The Walt Disney Company. Topics of features generally concern geography, history, nature, science, and world culture. The magazine is well known for its distinctive appearance: a thick squa ...
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Leukemia
Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ''leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia— acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myeloi ...
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Soft-shell Clam
Soft-shell clams (American English) or sand gaper (British English/Europe), scientific name ''Mya arenaria'', popularly called "steamers", "softshells", "piss clams", "Ipswich clams", or "Essex clams" are a species of edible saltwater clam, a marine bivalve mollusk in the family Myidae. Habitat and distribution These clams live buried in the sediment on tidal flats. While they are common in muddy areas, their name "arenaria" means sandy and they prefer a combination of sandy and muddy areas. They are well known as a food item on the coast of New England in the Western Atlantic Ocean; however, the range extends much farther north to Canada and south to the Southern states. They are also found in the Eastern Atlantic Ocean, for example in the UK, as well as in the North Sea's Wadden Sea (where they are the dominant large clam). This species has become invasive on the Pacific Coast of North America, including Alaska, Canada and the continental United States. However ''M. arena ...
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Devil Facial Tumour Disease
Devil facial tumour disease (DFTD) is an aggressive non-viral clonally transmissible cancer which affects Tasmanian devils, a marsupial native to Australia. DFTD was first described in 1996. In the subsequent decade the disease ravaged Tasmania's wild devils. Affected high-density populations had up to 100% mortality in 12–18 months. Between 1996 and 2015, DFTD wiped out 95% of affected populations. Clinical signs There is often more than one primary tumour. Visible signs of DFTD begin with lumps of soft tissue around the mouth, which ulcerate. Tumours are locally aggressive, destroying the underlying bone of the jaw which interferes with feeding. Tumours may also cover the eyes. Devils usually die within six months from organ failure, secondary infection, or metabolic starvation. DFTD is rare in juveniles. It affects males and females equally. Transmission The most plausible route of transmission is through biting, particularly when canine teeth come into direct contact with ...
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Aedes Aegypti
''Aedes aegypti'', the yellow fever mosquito, is a mosquito that can spread dengue fever, chikungunya, Zika fever, Mayaro and yellow fever viruses, and other disease agents. The mosquito can be recognized by black and white markings on its legs and a marking in the form of a lyre on the upper surface of its thorax. This mosquito originated in Africa, but is now found in tropical, subtropical and temperate regions throughout the world. Biology ''Aedes aegypti'' is a long, dark mosquito which can be recognized by white markings on its legs and a marking in the form of a lyre on the upper surface of its thorax. Females are larger than males. Microscopically females possess small palps tipped with silver or white scales, and their antennae have sparse short hairs, whereas those of males are feathery. ''Aedes aegypti'' can be mixed up with Aedes albopictus without a magnifying glass: The latter have a white stripe on the top of the mid thorax. Males live off fruit and only the f ...
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Contagious Reticulum Cell Sarcoma
Contagious reticulum cell sarcoma is a reticulum-cell sarcoma found in Syrian hamsters that can be transmitted from one hamster to another. It was first described in 1945. Transmission from hamster to hamster can be through various mechanisms. It has been seen to spread within a laboratory population, presumably through gnawing at tumours and cannibalism. It can also be spread by means of the bite of the mosquito ''Aedes aegypti ''Aedes aegypti'', the yellow fever mosquito, is a mosquito that can spread dengue fever, chikungunya, Zika fever, Mayaro and yellow fever viruses, and other disease agents. The mosquito can be recognized by black and white markings on its le ...''. It is one of only three known transmissible cancers in mammals; the others are devil facial tumor disease, a cancer which occurs in Tasmanian devils, and canine transmissible venereal tumor in dogs and other canines. Unlike these other two, tumours with multiple, independent origins have been observed ...
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Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown ...
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Canine Transmissible Venereal Tumor
A canine transmissible venereal tumor (CTVT), also known as a transmissible venereal tumor (TVT), canine transmissible venereal sarcoma (CTVS), sticker tumor and infectious sarcoma, is a histiocytic tumor of the external genitalia of the dog and other canines, and is transmitted from animal to animal during mating. It is one of only three known transmissible cancers in mammals; the others are devil facial tumor disease, a cancer which occurs in Tasmanian devils, and contagious reticulum cell sarcoma of the Syrian hamster. The tumor cells are themselves the infectious agents, and the tumors that form are not genetically related to the host dog. Although the genome of a CTVT is derived from an individual canid (specifically from a population of Native American dogs with coyote contribution), it is now essentially living as a unicellular, asexually reproducing (but sexually transmitted) pathogen. Sequence analysis of the genome suggests it diverged from canids over 6,000 years ago; ...
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