Tohoku Medical Megabank Project
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Tohoku Medical Megabank Project
The Tohoku Medical Megabank Project is a national project in Japan. The mission of the Tohoku Medical Megabank (TMM) project is to carry out a long-term health survey in the Miyagi and Iwate prefectures, which were affected by the Great East Japan Earthquake, and provide the research infrastructure for the development of personalized medicine by establishing a biobank and conducting cohort studies. It started in 2012. The TMM project is conducted by Tohoku University's Tohoku Medical Megabank Organization (ToMMo) and Iwate Medical University's Iwate Tohoku Medical Megabank Organization (IMM). Projects The following cohort studies A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing ... and research projects are in progress or completed. Prospective cohort studies * Community-base ...
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Miyagi Prefecture
is a prefecture of Japan located in the Tōhoku region of Honshu. Miyagi Prefecture has a population of 2,305,596 (1 June 2019) and has a geographic area of . Miyagi Prefecture borders Iwate Prefecture to the north, Akita Prefecture to the northwest, Yamagata Prefecture to the west, and Fukushima Prefecture to the south. Sendai is the capital and largest city of Miyagi Prefecture, and the largest city in the Tōhoku region, with other major cities including Ishinomaki, Ōsaki, and Tome. Miyagi Prefecture is located on Japan's eastern Pacific coast and bounded to the west by the Ōu Mountains, the longest mountain range in Japan, with 24% of its total land area being designated as Natural Parks. Miyagi Prefecture is home to Matsushima Islands, a group of islands ranked as one of the Three Views of Japan, near the town of Matsushima. On 7 April, 2011 the biggest earthquake in Japan occurred. History Miyagi Prefecture was formerly part of the province of Mutsu. 2011 T ...
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Iwate Prefecture
is a prefecture of Japan located in the Tōhoku region of Honshu. It is the second-largest Japanese prefecture at , with a population of 1,210,534 (as of October 1, 2020). Iwate Prefecture borders Aomori Prefecture to the north, Akita Prefecture to the west, and Miyagi Prefecture to the south. Morioka is the capital and largest city of Iwate Prefecture; other major cities include Ichinoseki, Ōshū, and Hanamaki. Located on Japan's Pacific Ocean coast, Iwate Prefecture features the easternmost point of Honshu at Cape Todo, and shares the highest peaks of the Ōu Mountains—the longest mountain range in Japan—at the border with Akita Prefecture. Iwate Prefecture is home to famous attractions such as Morioka Castle, the Buddhist temples of Hiraizumi including Chūson-ji and Mōtsū-ji, the Fujiwara no Sato movie lot and theme park in Ōshū, and the Tenshochi park in Kitakami known for its huge, ancient cherry trees. Iwate has the lowest population density of any prefecture ...
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Great East Japan Earthquake
Great may refer to: Descriptions or measurements * Great, a relative measurement in physical space, see Size * Greatness, being divine, majestic, superior, majestic, or transcendent People * List of people known as "the Great" *Artel Great (born 1981), American actor Other uses * ''Great'' (1975 film), a British animated short about Isambard Kingdom Brunel * ''Great'' (2013 film), a German short film * Great (supermarket), a supermarket in Hong Kong * GReAT, Graph Rewriting and Transformation, a Model Transformation Language * Gang Resistance Education and Training Gang Resistance Education And Training, abbreviated G.R.E.A.T., provides a school-based, police officer instructed program that includes classroom instruction and various learning activities. Their intention is to teach the students to avoid gang ..., or GREAT, a school-based and police officer-instructed program * Global Research and Analysis Team (GReAT), a cybersecurity team at Kaspersky Lab *'' Great!'', a 20 ...
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Personalized Medicine
Personalized medicine, also referred to as precision medicine, is a medical model that separates people into different groups—with medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease. The terms personalized medicine, precision medicine, stratified medicine and P4 medicine are used interchangeably to describe this concept though some authors and organisations use these expressions separately to indicate particular nuances. While the tailoring of treatment to patients dates back at least to the time of Hippocrates, the term has risen in usage in recent years given the growth of new diagnostic and informatics approaches that provide understanding of the molecular basis of disease, particularly genomics. This provides a clear evidence base on which to stratify (group) related patients. Among the 14 Grand Challenges for Engineering, an initiative sponsored by National Academy of En ...
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Biobank
A biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine. Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms. Genome-wide association studies using data from tens or hundreds of thousands of individuals can identify these genetic associations as potential disease biomarkers. Many researchers struggled to acquire sufficient samples prior to the advent of biobanks. Biobanks have provoked questions on privacy, research ethics, and medical ethics. Viewpoints on what constitutes appropriate biobank ethics diverge. However, a consensus has bee ...
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Cohort Study
A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic. Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the causes of diseases in the first place, and to help provide pre-clinica ...
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Tohoku University
, or is a Japanese national university located in Sendai, Miyagi in the Tōhoku Region, Japan. It is informally referred to as . Established in 1907, it was the third Imperial University in Japan and among the first three Designated National Universities, along with the University of Tokyo and Kyoto University. Tohoku University is a Top Type university of the Top Global University Project, and since 2020 has been ranked the best university in Japan by Times Higher Education. In 2016, Tohoku University had 10 faculties, 16 graduate schools and 6 research institutes, with a total enrollment of 17,885 students. The university's three core values are "Research First (研究第一主義)," "Open-Doors (門戸開放)," and "Practice-Oriented Research and Education (実学尊重)." History On June 22, 1907(明治40年,''Mēji yonjyunen''), the university was established under the name by the Meiji government as the third Imperial University of Japan, following the Tokyo Imperi ...
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Iwate Medical University
is a private university in Morioka, Iwate, Japan. History The institution has its origins in a private medical school founded in 1901. The school was closed in 1912 and later re-established in 1928 as Iwate Medical College. In 1947 the college was reorganized into Iwate Medical University through Japanese education reform. Location The university is in the centre of Morioka City, the capital of Iwate Prefecture. In recent years the university has built a new campus in small town of Yahaba, some 10 km from the old campus. The new School of Pharmacy The basic requirement for pharmacists A pharmacist, also known as a chemist ( Commonwealth English) or a druggist (North American and, archaically, Commonwealth English), is a healthcare professional who prepares, controls and distribute ... was opened at this new campus, and it is expected that the entire university will move to the new campus in the near future. Facilities and education As its name suggest ...
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Cohort Studies
A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic. Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the causes of diseases in the first place, and to help provide pre-clinica ...
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Biobank Organizations
A biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine. Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms. Genome-wide association studies using data from tens or hundreds of thousands of individuals can identify these genetic associations as potential disease biomarkers. Many researchers struggled to acquire sufficient samples prior to the advent of biobanks. Biobanks have provoked questions on privacy, research ethics, and medical ethics. Viewpoints on what constitutes appropriate biobank ethics diverge. However, a consensus has bee ...
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Cohort Studies
A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic. Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the causes of diseases in the first place, and to help provide pre-clinica ...
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Medicine In Japan
The level of health in Japan is due to a number of factors including cultural habits, isolation, and a universal health care system. John Creighton Campbell, a professor at the University of Michigan and Tokyo University, told the New York Times in 2009 that Japanese people are the healthiest group on the planet. Japanese visit a doctor nearly 14 times a year, more than four times as often as Americans. Life expectancy in 2013 was 83.3 years - among the highest on the planet. A new measure of expected human capital calculated for 195 countries from 1990 to 2016 and defined for each birth cohort as the expected years lived from age 20 to 64 years and adjusted for educational attainment, learning or education quality, and functional health status was published by the Lancet in September 2018. Japan had the highest level of expected human capital among the 20 largest countries: 24.1 health, education, and learning-adjusted expected years lived between age 20 and 64 years. C ...
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