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Tinea Capitis
Tinea capitis (also known as "herpes tonsurans", "ringworm of the hair", "ringworm of the scalp", "scalp ringworm", and "tinea tonsurans") is a cutaneous fungal infection (dermatophytosis) of the scalp. The disease is primarily caused by dermatophytes in the genera ''Trichophyton'' and '' Microsporum'' that invade the hair shaft. The clinical presentation is typically single or multiple patches of hair loss, sometimes with a 'black dot' pattern (often with broken-off hairs), that may be accompanied by inflammation, scaling, pustules, and itching. Uncommon in adults, tinea capitis is predominantly seen in pre-pubertal children, more often boys than girls. At least eight species of dermatophytes are associated with tinea capitis. Cases of ''Trichophyton'' infection predominate from Central America to the United States and in parts of Western Europe. Infections from ''Microsporum'' species are mainly in South America, Southern and Central Europe, Africa and the Middle East. The dise ...
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Fungus
A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from the other eukaryotic kingdoms, which by one traditional classification include Plantae, Animalia, Protozoa, and Chromista. A characteristic that places fungi in a different kingdom from plants, bacteria, and some protists is chitin in their cell walls. Fungi, like animals, are heterotrophs; they acquire their food by absorbing dissolved molecules, typically by secreting digestive enzymes into their environment. Fungi do not photosynthesize. Growth is their means of mobility, except for spores (a few of which are flagellated), which may travel through the air or water. Fungi are the principal decomposers in ecological systems. These and other differences place fungi in a single group of related organisms, named the ''Eumycota'' (''tru ...
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Microsporosis
''Trichophyton'' is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia. Macroconidia are mostly borne laterally directly on the hyphae or on short pedicels, and are thin- or thick-walled, clavate to fusiform, and range from 4 to 8 by 8 to 50 μm in size. Macroconidia are few or absent in many species. Microconidia are spherical, pyriform to clavate or of irregular shape, and range from 2 to 3 by 2 to 4 μm in size. Species and their habitat preference According to current classification, the genus includes anthropophilic and zoophilic species. Anthropophilic fungi prefer to infect humans. Zoophilic fungi prefer to infect animals other than humans. Humans and animals are natural reservoirs for parasitic or dermatophytic fungi. Other accep ...
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Trichophyton Equinum
''Trichophyton'' is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia. Macroconidia are mostly borne laterally directly on the hyphae or on short pedicels, and are thin- or thick-walled, clavate to fusiform, and range from 4 to 8 by 8 to 50 μm in size. Macroconidia are few or absent in many species. Microconidia are spherical, pyriform to clavate or of irregular shape, and range from 2 to 3 by 2 to 4 μm in size. Species and their habitat preference According to current classification, the genus includes anthropophilic and zoophilic species. Anthropophilic fungi prefer to infect humans. Zoophilic fungi prefer to infect animals other than humans. Humans and animals are natural reservoirs for parasitic or dermatophytic fungi. Other accep ...
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Microsporum Gypseum
''Microsporum gypseum'' is a soil-associated dermatophyte that occasionally is known to colonise and infect the upper dead layers of the skin of mammals. The name refers to an asexual "form-taxon" that has been associated with four related biological species of fungi: the pathogenic taxa '' Arthroderma incurvatum'', '' A. gypsea'', '' A. fulva'' and the non-pathogenic saprotroph '' A. corniculata''. More recent studies have restricted ''M. gypseum'' to two teleomorphic species ''A. gypseum'' and ''A. incurvatum''. The conidial states of ''A. fulva'' and ''A. corniculata'' have been assigned to ''M. fulvum'' and ''M. boullardii''. Because the anamorphic states of these fungi are so similar, they can be identified reliably only by mating. Two mating strains have been discovered, "+" and "–". The classification of this species has been based on the characteristically rough-walled, blunt, club-shaped, multicelled macroconidia. Synonyms include ''Achorion gypseum'', ''Microsporum ...
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Microsporum Canis
''Microsporum canis'' is a pathogenic, asexual fungus in the phylum Ascomycota that infects the upper, dead layers of skin on domesticated cats, and occasionally dogs and humans. The species has a worldwide distribution. Taxonomy and evolution ''Microsporum canis'' reproduces by means of two conidial forms, large, spindle-shaped, multicelled macroconidia and small, single-celled microconidia. First records of ''M. canis'' date to 1902. Evolutionary studies have established that ''M. canis'', like the very closely related sibling species ''M. distortum'' and ''M. equinum'', is a genetic clone derived from the sexually reproducing species, ''Arthroderma otae''. Members of Ascomycota often possess conspicuous asexual and sexual forms that can coexist in time and space. ''Microsporum canis'' exemplifies a common situation in ascomycetous fungi in which, over time, one mating type strain has undergone habitat divergence from the other and established a self-sustaining reproductive p ...
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Wood's Lamp
A blacklight, also called a UV-A light, Wood's lamp, or ultraviolet light, is a lamp that emits long-wave (UV-A) ultraviolet light and very little visible light. One type of lamp has a violet filter material, either on the bulb or in a separate glass filter in the lamp housing, which blocks most visible light and allows through UV, so the lamp has a dim violet glow when operating. Blacklight lamps which have this filter have a lighting industry designation that includes the letters "BLB". This stands for "blacklight blue". A second type of lamp produces ultraviolet but does not have the filter material, so it produces more visible light and has a blue color when operating. These tubes are made for use in "bug zapper" insect traps, and are identified by the industry designation "BL". This stands for "blacklight". Blacklight sources may be specially designed fluorescent lamps, mercury-vapor lamps, light-emitting diodes (LEDs), lasers, or incandescent lamps. In medicine, f ...
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Arthroconidia
Arthroconidia are a type of fungal spore typically produced by segmentation of pre-existing fungal hyphae. Background These spores are asexual and are generally not as durable and environmentally persistent as, for instance, bacterial endospores or chlamydospores. Some medically significant pathogens, such as ''Coccidioides immitis'', and ''Coccidioides posadasii'', both causative agents of coccidioidomycosis (also known as San Joaquin Valley fever), are transmitted through airborne arthroconidia. The small size of the arthroconidia, 3 to 5 µm, allow them to lodge themselves into the terminal bronchioles of the lung. There, they develop into a thick-walled spherule filled with endospores that cause a pyogenic (pus-causing) inflammation. See also *Conidium A conidium ( ; ), sometimes termed an asexual chlamydospore or chlamydoconidium (), is an Asexual reproduction, asexual, non-motility, motile spore of a fungus. The word ''conidium'' comes from the Ancient Greek word ...
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Stratum Corneum
The stratum corneum (Latin for 'horny layer') is the outermost layer of the epidermis. The human stratum corneum comprises several levels of flattened corneocytes that are divided into two layers: the ''stratum disjunctum'' and ''stratum compactum''. The skin's protective acid mantle and lipid barrier sit on top of the stratum disjunctum. The stratum disjunctum is the uppermost and loosest layer of skin. The stratum compactum is the comparatively deeper, more compacted and more cohesive part of the stratum corneum. The corneocytes of the stratum disjunctum are larger, more rigid and more hydrophobic than that of the stratum compactum. The stratum corneum is the dead tissue that performs protective and adaptive physiological functions including mechanical shear, impact resistance, water flux and hydration regulation, microbial proliferation and invasion regulation, initiation of inflammation through cytokine activation and dendritic cell activity, and selective permeability to e ...
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Scutula
''Scutula'' is a genus of lichenicolous fungi in the family Ramalinaceae. Taxonomy The genus ''Scutula'' was circumscribed by French botanist Louis René Étienne Tulasne in 1862. The limits of the generic circumscription as well as the limits of certain species in ''Scutula'' was confused for a long time. In 1997, Triebel and colleagues applied the name ''Scutula'' specifically to a group of species growing on hosts of the Lecanorales suborder Peltigerineae, a monophyletic grouping of cyanobacteria-associated lichens. Before this, ''Scutula'' was applied to a diverse set of unrelated lichenicolous fungi featuring hyaline spores with a single septum and sessile apothecia. Once classified in the family Micareaceae, molecular phylogenetic analysis showed ''Scutula'' to be nested within the Ramalinaceae, closely related to the genus '' Toninia''. This familial placement has been accepted in recent large-scale updates of fungal classifications. Description ''Scutula'' speci ...
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Hair Follicle
The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction between hormones, neuropeptides, and immune cells. This complex interaction induces the hair follicle to produce different types of hair as seen on different parts of the body. For example, terminal hairs grow on the scalp and lanugo hairs are seen covering the bodies of fetuses in the uterus and in some newborn babies. The process of hair growth occurs in distinct sequential stages. The first stage is called ''anagen'' and is the active growth phase, ''telogen'' is the resting stage, ''catagen'' is the regression of the hair follicle phase, ''exogen'' is the active shedding of hair phase and lastly ''kenogen'' is the phase between the empty hair follicle and the growth of new hair. The function of hair in humans has long been a subject of int ...
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Trichophyton Tonsurans
''Trichophyton tonsurans'' is a fungus in the family Arthrodermataceae that causes ringworm infection of the scalp. It was first recognized by David Gruby in 1844. Isolates are characterized as the "–" or negative mating type of the '' Arthroderma vanbreuseghemii'' complex. This species is thought to be conspecific with '' T. equinum'', although the latter represents the "+" mating strain of the same biological species Despite their biological conspecificity, clones of the two mating types appear to have undergone evolutionary divergence with isolates of the ''T. tonsurans''-type consistently associated with Tinea capitis (particularly in children) whereas the ''T. equinum''-type, as its name implies, is associated with horses as a regular host. Phylogenetic relationships were established in isolates from Northern Brazil, through fingerprinting polymorphic RAPD and M13 markers. There seems to be lower genomic variability in the ''T. tonsurans'' species due to allopatric diverge ...
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Microsporum Audouinii
''Microsporum audouinii'' is an anthropophilic fungus in the genus ''Microsporum''. It is a type of dermatophyte that colonizes keratinized tissues (primarily hair) causing infection. The fungus is characterized by its spindle-shaped macroconidia (7–30 × 35–160 μm), clavate microconidia (2.5–3.5 × 4–7 μm) as well as its pitted or spiny external walls. Growth conditions This fungus is often found in soil that is rich in keratinous material. However, there are other factors that can influence its growth, such as pH, relative humidity, organic carbon, nitrogen and temperature. ''Microsporum audouinii'' appears to prefer a neutral pH in the range of 6.8-7.0 and room temperature for growth. Drastic increases or decreases in temperature can inhibit its growth. ''Microsporum audouinii'' is effective in utilizing its carbon sources, but growth is strongest in the hexoses (glucose, mannose and fructose) and weakest in maltose, sucrose, lactose and galactose. It is u ...
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