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Thérèse Tréfouël
Thérèse Tréfouël (née Boyer, 19 June 1892 — 9 November 1978) was a French chemist. Along with her husband, Jacques Tréfouël, she is best known for her research on sulfamides, a novel class of antibiotic drugs. Education and personal life Between 1913 and 1919, Tréfouël studied chemistry at the Faculté des Sciences, in Paris. She met her husband Jacques when they were assigned as lab partners after both failing to sign up to a practical course on time. Jacques and Thérèse married in 1921. They were known for the strength of their partnership and collaboration. Even after their retirement from scientific research, the Tréfouëls continued to collaborate on various projects: Jacques was fascinated by metalwork and woodwork, and would construct furniture which Thérèse upholstered. Research and career In the early 1920s, Thérèse and her husband worked at the Pasteur Institute, in the laboratory of Ernest Fourneau — known as the father of medicinal chemistry. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Daniel Bovet
Daniel Bovet (23 March 1907 – 8 April 1992) was a Swiss-born Italian pharmacologist who won the 1957 Nobel Prize in Physiology or Medicine for his discovery of drugs that block the actions of specific neurotransmitters. He is best known for his discovery in 1937 of antihistamines, which block the neurotransmitter histamine and are used in allergy medication. His other research included work on chemotherapy, sulfa drugs, the sympathetic nervous system, the pharmacology of curare, and other neuropharmacological interests. In 1965, Bovet led a study team which concluded that smoking of tobacco cigarettes increased users' intelligence. He told ''The New York Times'' that the object was not to "create geniuses, but only oput the less-endowed individual in a position to reach a satisfactory mental and intellectual development". Bovet was born in Fleurier, Switzerland. He was a native Esperanto speaker. He graduated from the University of Geneva in 1927 and received his doctorate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1978 Deaths
Events January * January 1 – Air India Flight 855, a Boeing 747 passenger jet, crashes off the coast of Bombay, killing 213. * January 5 – Bülent Ecevit, of Republican People's Party, CHP, forms the new government of Turkey (42nd government). * January 6 – The Holy Crown of Hungary (also known as Stephen of Hungary Crown) is returned to Hungary from the United States, where it was held since World War II. * January 10 – Pedro Joaquín Chamorro Cardenal, a critic of the Nicaraguan government, is assassinated; riots erupt against Anastasio Somoza Debayle, Somoza's government. * January 18 – The European Court of Human Rights finds the British government guilty of mistreating prisoners in Northern Ireland, but not guilty of torture. * January 22 – Ethiopia declares the ambassador of West Germany ''persona non grata''. * January 24 ** Soviet Union, Soviet satellite Kosmos 954 burns up in Earth's atmosphere, scattering debris over Canada's Northwest Territories. ** ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1892 Births
Year 189 ( CLXXXIX) was a common year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Silanus and Silanus (or, less frequently, year 942 ''Ab urbe condita''). The denomination 189 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * Plague (possibly smallpox) kills as many as 2,000 people per day in Rome. Farmers are unable to harvest their crops, and food shortages bring riots in the city. China * Liu Bian succeeds Emperor Ling, as Chinese emperor of the Han Dynasty. * Dong Zhuo has Liu Bian deposed, and installs Emperor Xian as emperor. * Two thousand eunuchs in the palace are slaughtered in a violent purge in Luoyang, the capital of Han. By topic Arts and sciences * Galen publishes his ''"Treatise on the various temperaments"'' (aka ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Place Jacques-et-Thérèse-Tréfouël
Place may refer to: Geography * Place (United States Census Bureau), defined as any concentration of population ** Census-designated place, a populated area lacking its own municipal government * "Place", a type of street or road name ** Often implies a dead end (street) or cul-de-sac * Place, based on the Cornish word "plas" meaning mansion * Place, a populated place, an area of human settlement ** Incorporated place (see municipal corporation), a populated area with its own municipal government * Location (geography), an area with definite or indefinite boundaries or a portion of space which has a name in an area Placenames * Placé, a commune in Pays de la Loire, Paris, France * Plače, a small settlement in Slovenia * Place (Mysia), a town of ancient Mysia, Anatolia, now in Turkey * Place, New Hampshire, a location in the United States * Place House, a 16th-century mansion largely remodelled in the 19th century, in Fowey, Cornwall * Place House, a 19th-century mansion on ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leprosy
Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria ''Mycobacterium leprae'' or ''Mycobacterium lepromatosis''. Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. This nerve damage may result in a lack of ability to feel pain, which can lead to the loss of parts of a person's extremities from repeated injuries or infection through unnoticed wounds. An infected person may also experience muscle weakness and poor eyesight. Leprosy symptoms may begin within one year, but, for some people, symptoms may take 20 years or more to occur. Leprosy is spread between people, although extensive contact is necessary. Leprosy has a low pathogenicity, and 95% of people who contract ''M. leprae'' do not develop the disease. Spread is thought to occur through a cough or contact with fluid from the nose of a person infected by leprosy. Genetic factors and immune function play a role in how easily a person catches the disease. Lepro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dapsone
Dapsone, also known as 4,4'-sulfonyldianiline (SDA) or diaminodiphenyl sulfone (DDS), is an antibiotic commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. It is a second-line medication for the treatment and prevention of pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne, dermatitis herpetiformis, and various other skin conditions. Dapsone is available both topically and by mouth. Severe side effects may include a decrease in blood cells, red blood cell breakdown especially in those with glucose-6-phosphate dehydrogenase deficiency (G-6-PD), or hypersensitivity. Common side effects include nausea and loss of appetite. Other side effects include liver inflammation, methemoglobinemia, and a number of types of skin rashes. While the safety of use during pregnancy is not entirely clear some physicians recommend that it be continued in those with l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies and the Axis powers. World War II was a total war that directly involved more than 100 million personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the only two nuclear weapons ever used in war. World War II was by far the deadliest conflict in human history; it resulted in 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvation, ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections. They may either kill or inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the common cold or influenza; drugs which inhibit viruses are termed antiviral drugs or antivirals rather than antibiotics. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against microbes, but in the usual medical usage, antibiotics (such as penicillin) are those produced naturally (by one microorganism fighting another), whereas non-antibiotic antibacterials (such as sulfonamides and antiseptics) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
