Therapeutic Use Exemptions
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Therapeutic Use Exemptions
A therapeutic use exemption (TUE), also known as a temporary use exemption, is a term created in 1991 and refers to an official medical document. The document gives an athlete permission to take a medication listed on the World Anti-Doping Agency’s (WADA) Prohibited List, normally prohibited because its use would be considered a performance enhancing drug. In 2017, the ''Australian and New Zealand Sports Law Journal'' referred to the abuse of TUEs as “The Legal Dope”. An example of a TUE is the World Anti-Doping Agency's exemption for testosterone replacement therapy. The average for a normal functioning male is a 1:1 ratio, but WADA allows up to a 4:1 ratio without testing positive for elevated testosterone. Mixed martial arts do not have as stringent anti-doping regulations as most other sports. The ''Journal of Legal Medicine'' quotes Dr. Johnny Benjamin, a medical journalist, as stating that in regards to TUEs in mixed martial arts, “TRT is far too easily abused”. ...
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List Of Drugs Banned By The World Anti-Doping Agency
The International Standard for the Prohibited List is the standard published by the World Anti-Doping Agency (WADA) that lists substances prohibited in competitive sport. It is updated at least once per year as required by the World Anti-Doping Code. The adoption of the first World Anti-Doping Code (the Code) occurred at the 2nd World Conference on Doping in Sport in March 2003 in Copenhagen, Denmark. It was there that WADA assumed the responsibility of maintaining, updating, and publishing the List of Prohibited Substances and Methods (the List) in sport. The List is to be updated and published by WADA at least annually. WADA specifies that the List generally includes any substance that meets any two of the following criteria: it enhances sport performance, it represents a health risk to the athlete, it violates the spirit of sport (as defined in the WADA Code). Substances and techniques that are prohibited by WADA fall into the following categories: androgens, blood doping, peptid ...
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Performance Enhancing Drug
Performance-enhancing substances, also known as performance-enhancing drugs (PEDs), are substances that are used to improve any form of activity performance in humans. A well-known example of cheating in sports involves doping in sport, where banned physical performance-enhancing drugs are used by athletes and bodybuilders. Athletic performance-enhancing substances are sometimes referred to as ergogenic aids. Cognitive performance-enhancing drugs, commonly called nootropics, are sometimes used by students to improve academic performance. Performance-enhancing substances are also used by military personnel to enhance combat performance. The use of performance-enhancing drugs spans the categories of legitimate use and substance abuse. Definition The classifications of substances as performance-enhancing substances are not entirely clear-cut and objective. As in other types of categorization, certain prototype performance enhancers are universally classified as such (like anaboli ...
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World Anti-Doping Agency
The World Anti-Doping Agency (WADA; french: Agence mondiale antidopage, AMA) is a foundation initiated by the International Olympic Committee based in Canada to promote, coordinate, and monitor the fight against drugs in sports. The agency's key activities include scientific research, education, development of anti-doping capacities, and monitoring of the World Anti-Doping Code, whose provisions are enforced by the UNESCO International Convention Against Doping in Sport. The aims of the Council of Europe Anti-Doping Convention and the United States Anti-Doping Agency are also closely aligned with those of WADA. History The World Anti-Doping Agency is a foundation created through a collective initiative led by the International Olympic Committee (IOC). It was set up on 10 November 1999 in Lausanne, Switzerland, as a result of what was called the "Declaration of Lausanne", to promote, coordinate and monitor the fight against drugs in sports. Since 2002, the organization's head ...
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Testosterone Replacement Therapy
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT) or hormone replacement therapy (HRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced exogenously. ART is often prescribed to counter the effects of male hypogonadism. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets. ART is also prescribed to lessen the effects or delay the onset of normal male aging. However, this is controversial and is the subject of ongoing clinical trials. As men enter middle age they may notice changes caused by a relative decline in testosterone: fewer erections, fatigue, thinning skin, declining muscle mass and strength, and/or more body fat. Dissatisfaction with these changes causes some middle age men to seek ART. Androgen deficiencies in women have also, as of 2001, been recognized as a medical disorder that can be treat ...
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Mixed Martial Arts
Mixed martial arts (MMA), sometimes referred to as cage fighting, no holds barred (NHB), and ultimate fighting, and originally referred to as Vale Tudo is a full-contact combat sport based on striking, grappling and ground fighting, incorporating techniques from various combat sports from around the world. The first documented use of the term ''mixed martial arts'' was in a review of UFC 1 by television critic Howard Rosenberg in 1993. The question of who actually coined the term is subject to debate. During the early 20th century, various interstylistic contests took place throughout Japan and in the countries of the Four Asian Tigers. In Brazil, there was the sport of Vale Tudo, in which The Gracie family was known to promote Vale Tudo matches as a way to promote their own Brazilian jiu-jitsu style. A precursor to modern MMA was the 1976 Ali vs. Inoki exhibition bout (which ended in a draw after 15 rounds), fought between boxer Muhammad Ali and wrestler Antonio ...
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Journal Of Legal Medicine
The ''Journal of Legal Medicine'' is a quarterly peer-reviewed academic journal covering legal medicine and medical law. It was established in 1979 and is published by Taylor & Francis on behalf of the American College of Legal Medicine, of which it is the official journal. The editor-in-chief is Leslie E. Wolf. According to the ''Journal Citation Reports'', the journal has a 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 0.417. References External links *{{Official website, 1=https://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=ulgm20 Taylor & Francis academic journals Medical law journals Publications established in 1979 Quarterly journals English-language journals Academic journals associated with learned and profess ...
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Fancy Bear
Fancy Bear (also known as APT28 (by Mandiant), Pawn Storm, Sofacy Group (by Kaspersky), Sednit, Tsar Team (by FireEye) and STRONTIUM (by Microsoft)) is a Russian cyber espionage group. Cybersecurity firm CrowdStrike has said with a medium level of confidence that it is associated with the Russian military intelligence agency GRU. The UK's Foreign and Commonwealth Office as well as security firms SecureWorks, ThreatConnect, and Mandiant, have also said the group is sponsored by the Russian government. In 2018, an indictment by the United States Special Counsel identified Fancy Bear as GRU Unit 26165. The name "Fancy Bear" comes from a coding system security researcher Dmitri Alperovitch uses to identify hackers. Likely operating since the mid-2000s, Fancy Bear's methods are consistent with the capabilities of state actors. The group targets government, military, and security organizations, especially Transcaucasian and NATO-aligned states. Fancy Bear is thought to be responsible ...
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Bradley Wiggins
Sir Bradley Marc Wiggins, CBE (born 28 April 1980) is a British former professional road and track racing cyclist, who competed professionally between 2001 and 2016. He began his cycling career on the track, but later made the transition to road cycling. He won world titles in four disciplines (Madison, individual pursuit, team pursuit and road time trial), and Olympic gold in three (individual pursuit, team pursuit and road time trial). He is the only rider to have won both World and Olympic championships on both the track and the road as well as winning the Tour de France. He has worn the leader's jersey in each of the three Grand Tours of cycling and held the world record in team pursuit on multiple occasions. He won a gold medal at four successive Olympic Games from 2004 to 2016, and held the record as Great Britain's most decorated Olympian with 8 medals until Jason Kenny won his 9th in 2021. He is the only rider to win both the Tour de France and Olympic Gold in the same ...
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Corticosteroid
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. Some common naturally occurring steroid hormones are cortisol (), corticosterone (), cortisone () and aldosterone (). (Note that cortisone and aldosterone are isomers.) The main corticosteroids produced by the adrenal cortex are cortisol and aldosterone. Classes * Glucocorticoids such as cortisol affect carbohydrate, fat, and protein metabolism, and have anti-inflammatory, immunosuppressive, anti-proliferative, and vasoconstrictive effects. Anti-inflammatory effects are mediated by blocking the action of inflammatory medi ...
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Triamcinolone Acetonide
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions. It is also injected into lesions to treat inflammation in some parts of the body, particularly the skin. In nasal spray form, it is used to treat allergic rhinitis. It is used for the treatment of macular edema associated with uveitis. It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone. Most forms of triamcinolone acetonide are Prescription drug, prescription drugs. In 2014, the U.S. Food and Drug Administration (FDA) made triamcinolone acetonide an over-the-counter drug in the United States in nasal spray form under the brand name Nasacort. Medical uses Triamcinolone acetonide as an intra-articular injectable has been used to treat a variety of musculoskeletal ...
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Adderall
Adderall and Mydayis are trade names for a combination drug called mixed amphetamine salts containing four salts of amphetamine. The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. Both enantiomers are stimulants, but differ enough to give Adderall an effects profile distinct from those of racemic amphetamine or dextroamphetamine, which are marketed as Evekeo and Dexedrine/Zenzedi, respectively. Adderall is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used illicitly as an athletic performance enhancer, cognitive enhancer, appetite suppressant, and recreationally as a euphoriant. It is a central nervous system (CNS) stimulant of the phenethylamine class. Adderall is generally well-tolerated and effective in treating symptoms of ADHD and narcolepsy. At therapeutic doses, Adderall c ...
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Major League Baseball
Major League Baseball (MLB) is a professional baseball organization and the oldest major professional sports league in the world. MLB is composed of 30 total teams, divided equally between the National League (NL) and the American League (AL), with 29 in the United States and 1 in Canada. The NL and AL were formed in 1876 and 1901, respectively. Beginning in 1903, the two leagues signed the National Agreement and cooperated but remained legally separate entities until 2000, when they merged into a single organization led by the Commissioner of Baseball. MLB is headquartered in Midtown Manhattan. It is also included as one of the major professional sports leagues in the United States and Canada. Baseball's first all-professional team, the Cincinnati Red Stockings, was founded in 1869. Before that, some teams had secretly paid certain players. The first few decades of professional baseball were characterized by rivalries between leagues and by players who often jumped from one te ...
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