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Theodore Leber
Theodor Karl Gustav von Leber (29 February 1840 – 17 April 1917) was a German ophthalmologist from Karlsruhe. Leber was a student of Hermann von Helmholtz (1821-1894) in Heidelberg, where he received his doctorate in 1862. He remained in Heidelberg as an assistant to Hermann Jakob Knapp (1832-1911) at the Heidelberg eye clinic, afterwards studying physiology under Carl Ludwig (1816-1895) in Vienna. From 1867 until 1870 he was an assistant to ophthalmologist Albrecht von Graefe (1828-1870) in Berlin. In 1871, he became director of the university eye clinic in Göttingen, and from 1890 to 1910 was director of the eye clinic in Heidelberg. Leber was the first to describe what is now known as Leber's congenital amaurosis in 1869 and Leber's hereditary optic neuropathy in 1871.Man PY, Turnbull DM, Chinnery PF"Leber hereditary optic neuropathy." ''J Med Genet.'' 2002 Mar;39(3):162-9. . An anatomical structure called "Leber's plexus" is named after him, which is a small venous plexus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leber's Hereditary Optic Neuropathy
Leber's hereditary optic neuropathy (LHON) is a mitochondrially inherited (transmitted from mother to offspring) degeneration of retinal ganglion cells (RGCs) and their axons that leads to an acute or subacute loss of central vision; it predominantly affects young adult males. LHON is transmitted only through the mother, as it is primarily due to mutations in the mitochondrial (not nuclear) genome, and only the egg contributes mitochondria to the embryo. LHON is usually due to one of three pathogenic mitochondrial DNA (mtDNA) point mutations. These mutations are at nucleotide positions 11778 G to A, 3460 G to A and 14484 T to C, respectively in the ND4, ND1 and ND6 subunit genes of complex I of the oxidative phosphorylation chain in mitochondria. Men cannot pass on the disease to their offspring. Signs and symptoms Clinically, there is an acute onset of visual loss, first in one eye, and then a few weeks to months later in the other. Onset is usually young adulthood, b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heidelberg University Faculty
Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914, of which roughly a quarter consisted of students. Located about south of Frankfurt, Heidelberg is the List of cities in Baden-Württemberg by population, fifth-largest city in Baden-Württemberg. Heidelberg is part of the densely populated Rhine-Neckar, Rhine-Neckar Metropolitan Region. Heidelberg University, founded in 1386, is Germany's oldest and one of Europe's most reputable universities. Heidelberg is a Science, scientific hub in Germany and home to several internationally renowned #Research, research facilities adjacent to its university, including the European Molecular Biology Laboratory and four Max Planck Society, Max Planck Institutes. The city has also been a hub for the arts, especially literature, throughout the centurie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heidelberg University Alumni
Heidelberg (; Palatine German language, Palatine German: ''Heidlberg'') is a city in the States of Germany, German state of Baden-Württemberg, situated on the river Neckar in south-west Germany. As of the 2016 census, its population was 159,914, of which roughly a quarter consisted of students. Located about south of Frankfurt, Heidelberg is the List of cities in Baden-Württemberg by population, fifth-largest city in Baden-Württemberg. Heidelberg is part of the densely populated Rhine-Neckar, Rhine-Neckar Metropolitan Region. Heidelberg University, founded in 1386, is Germany's oldest and one of Europe's most reputable universities. Heidelberg is a Science, scientific hub in Germany and home to several internationally renowned #Research, research facilities adjacent to its university, including the European Molecular Biology Laboratory and four Max Planck Society, Max Planck Institutes. The city has also been a hub for the arts, especially literature, throughout the centurie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From The Grand Duchy Of Baden
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physicians From Karlsruhe
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Ophthalmologists
German(s) may refer to: * Germany (of or related to) **Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * Germa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1917 Deaths
Events Below, the events of World War I have the "WWI" prefix. January * January 9 – WWI – Battle of Rafa: The last substantial Ottoman Army garrison on the Sinai Peninsula is captured by the Egyptian Expeditionary Force's Desert Column. * January 10 – Imperial Trans-Antarctic Expedition: Seven survivors of the Ross Sea party were rescued after being stranded for several months. * January 11 – Unknown saboteurs set off the Kingsland Explosion at Kingsland (modern-day Lyndhurst, New Jersey), one of the events leading to United States involvement in WWI. * January 16 – The Danish West Indies is sold to the United States for $25 million. * January 22 – WWI: United States President Woodrow Wilson calls for "peace without victory" in Germany. * January 25 ** WWI: British armed merchantman is sunk by mines off Lough Swilly (Ireland), with the loss of 354 of the 475 aboard. ** An anti-prostitution drive in San Francisco occurs, and police ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1840 Births
__NOTOC__ Year 184 ( CLXXXIV) was a leap year starting on Wednesday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Eggius and Aelianus (or, less frequently, year 937 ''Ab urbe condita''). The denomination 184 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place China * The Yellow Turban Rebellion and Liang Province Rebellion break out in China. * The Disasters of the Partisan Prohibitions ends. * Zhang Jue leads the peasant revolt against Emperor Ling of Han of the Eastern Han Dynasty. Heading for the capital of Luoyang, his massive and undisciplined army (360,000 men), burns and destroys government offices and outposts. * June – Ling of Han places his brother-in-law, He Jin, in command of the imperial army and sends them to attack the Yellow Turban rebels. * Winter – Zha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Felice Fontana
Abbé Gasparo Ferdinando Felice Fontana (15 April 1730 – 9 March 1805) was an Italian polymath who contributed to experimental studies in physiology, toxicology, and physics. As a physicist he discovered the water gas shift reaction in 1780. He investigated the human eye and has also been credited with discovering the nucleolus of a cell. His work on the venom of vipers was among the earliest experimental toxicological studies. He served as a court physicist for Leopold II, Holy Roman Emperor, Peter Leopold, Duke of Tuscany and taught at the University of Pisa. He was involved in the establishment of the La Specola museum in Florence. Biography Fontana was born at Casa Fontana, Pomarolo, Vallagarina (district), Val Lagarina, the third son of jurist Pietro and his wife Elena Caterina Ienetti. He was baptized on 3 June 1730. When his father moved to Villa Lagarina, Fontana studied in Rovereto under Girolamo Tartarotti and Giambattista Graser. He then travelled to listened to lectu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trabecular Meshwork
The trabecular meshwork is an area of tissue in the eye located around the base of the cornea, near the ciliary body, and is responsible for draining the aqueous humor from the eye via the anterior chamber (the chamber on the front of the eye covered by the cornea). The tissue is spongy and lined by trabeculocytes; it allows fluid to drain into a set of tubes called Schlemm's canal which is lined by endothelium with blood and lymphatic properties that allow aqueous humor to flow into the blood system. Structure The meshwork is divided up into three parts, with characteristically different ultrastructures: #''Inner uveal meshwork'' - Closest to the anterior chamber angle, contains thin cord-like trabeculae, orientated predominantly in a radial fashion, enclosing trabeculae spaces larger than the corneoscleral meshwork. #''Corneoscleral meshwork'' - Contains a large amount of elastin, arranged as a series of thin, flat, perforated sheets arranged in a laminar pattern; cons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Friedrich Schlemm
Friedrich Schlemm (11 December 1795 – 27 May 1858) was a German anatomist who was professor at the University of Berlin. He was born in Salzgitter. As his family could not afford higher education, he was apprenticed to a barber-surgeon in Braunschweig. This gave him the opportunity to study anatomy and surgery at the local Anatomico-Surgical Institute. In 1821 he received his medical doctorate from the University of Berlin, and became Prosector at the university in 1823. In 1829 he became "professor extraordinary" of anatomy, and attained the title of "full professor" in 1833. Recently discovered archival sources demonstrate that, in June 1816, Schlemm and a fellow student disinterred the body of a deceased woman late at night in a Braunschweig churchyard to bring the body to this Institute and study the effects of rickets on the woman's bones. They were caught and sentenced to 4 weeks of prison. Subsequently, Schlemm left Braunschweig and found work as a low-rank army surgeon i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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