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The Skin I Live In
''The Skin I Live In'' ( es, link=no, La piel que habito) is a 2011 Spanish science fiction psychological thriller film written and directed by Pedro Almodóvar, starring Antonio Banderas, Elena Anaya, Marisa Paredes, Jan Cornet and Roberto Álamo. It is based on Thierry Jonquet's 1984 novel ''Mygale'', first published in French and then in English under the title ''Tarantula''. Almodóvar has described the film as "a horror story without screams or frights". The film was the first collaboration in 21 years between Almodóvar and Banderas since ''Tie Me Up! Tie Me Down!'' (1990). It premiered in May 2011 in competition at the 64th Cannes Film Festival, and won Best Film Not in the English Language at the 65th BAFTA Awards. It was also nominated for the Golden Globe Award for Best Foreign Language Film and 16 Goya Awards. Plot Plastic surgeon Robert Ledgard was successful in cultivating an artificial skin resistant to burns and insect bites, which he calls "GAL", that he says h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pedro Almodóvar
Pedro Almodóvar Caballero (; (often known simply as Almodóvar) born 25 September 1949) is a Spanish filmmaker. His films are marked by melodrama, irreverent humour, bold colour, glossy décor, quotations from popular culture, and complex narratives. Desire, passion, family, and identity are among Almodóvar's most prevalent subjects in his films. Acclaimed as one of the most internationally successful Spanish filmmakers, Almodóvar and his films have gained worldwide interest and developed a cult following. Almodóvar's career came to during La Movida Madrileña, a cultural renaissance that followed after the end of Francoist Spain. His early films characterised the sense of sexual and political freedom of the period. In 1986, he established his own film production company, El Deseo, with his younger brother Agustín Almodóvar, who has been responsible for producing all of his films since ''Law of Desire'' (1987). His breakthrough film was ''Women on the Verge of a Nervous B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Science Fiction Film
Science fiction (or sci-fi) is a film genre that uses speculative, fictional science-based depictions of phenomena that are not fully accepted by mainstream science, such as extraterrestrial lifeforms, spacecraft, robots, cyborgs, interstellar travel, time travel, or other technologies. Science fiction films have often been used to focus on political or social issues, and to explore philosophical issues like the human condition. The genre has existed since the early years of silent cinema, when Georges Melies' '' A Trip to the Moon'' (1902) employed trick photography effects. The next major example (first in feature length in the genre) was the film ''Metropolis'' (1927). From the 1930s to the 1950s, the genre consisted mainly of low-budget B movies. After Stanley Kubrick's landmark '' 2001: A Space Odyssey'' (1968), the science fiction film genre was taken more seriously. In the late 1970s, big-budget science fiction films filled with special effects became popular wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Posttraumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that can develop because of exposure to a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event. Young children are less likely to show distress but instead may express their memories through play. A person with PTSD is at a higher risk of suicide and intentional self-harm. Most people who experience traumatic events do not develop PTSD. People who experience interpersonal violence such as rape, other sexual assaults, being kidnapped, stalking, physical abuse by an intimate partner ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transgenesis
Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. Gene delivery must reach the genome of the host cell to induce gene expression. Successful gene delivery requires the foreign gene delivery to remain stable within the host cell and can either integrate into the genome or replicate independently of it. This requires foreign DNA to be synthesized as part of a vector, which is designed to enter the desired host cell and deliver the transgene to that cell's genome. Vectors utilized as the method for gene delivery can be divided into two categories, recombinant viruses and synthetic vectors (viral and non-viral). In complex multicellular eukaryotes (more specifically Weissmanists), if the transgene is incorporated into the host's germline cells, the resulting host cell can pass the transgene to its progeny. If the transgene is incorporated into somatic cells, the transgene will stay with the somatic cell line, and thus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Athymic Mice
A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune system due to a greatly reduced number of T cells. The phenotype (main outward appearance) of the mouse is a lack of body hair, which gives it the "nude" nickname. The nude mouse is valuable to research because it can receive many different types of tissue and tumor grafts, as it mounts no rejection response. These xenografts are commonly used in research to test new methods of imaging and treating tumors. The genetic basis of the nude mouse mutation is a disruption of the FOXN1 gene. Nomenclature The nomenclature for the nude mouse has changed several times since their discovery. Originally they were described as ''nu'' and this was updated to ''Hfh11nu'' when the mutated gene was identified as a mutation in the HNF-3/forkhead homolog 11 gene. Then in 2000 the gene responsible for the mutation was identified as a member of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artificial Skin
Artificial skin is a collagen scaffold that induces regeneration of skin in mammals such as humans. The term was used in the late 1970s and early 1980s to describe a new treatment for massive burns. It was later discovered that treatment of deep skin wounds in adult animals and humans with this scaffold induces regeneration of the dermis. It has been developed commercially under the name Integra and is used in massively burned patients, during plastic surgery of the skin, and in treatment of chronic skin wounds. Alternatively, the term "artificial skin" sometimes is used to refer to skin-like tissue grown in a laboratory, although this technology is still quite a way away from being viable for use in the medical field. 'Artificial skin' can also refer to flexible semiconductor materials that can sense touch for those with prosthetic limbs (also experimental). Background The skin is the largest organ in the human body. Skin is made up of three layers, the epidermis, dermis and the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Goya Awards
The Goya Awards ( es, Premios Goya) are Spain's main national annual film awards, commonly referred to as the Academy Awards of Spain. The awards were established in 1987, a year after the founding of the Academy of Cinematographic Arts and Sciences, and the first awards ceremony took place on March 16, 1987 at the Teatro Lope de Vega, Madrid. The ceremony continues to take place annually at Centro de Congresos Príncipe Felipe, around the end of January/beginning of February, and awards are given to films produced during the previous year. The award itself is a small bronze bust of Francisco Goya created by the sculptor José Luis Fernández, although the original sculpture for the first edition of the Goyas was by Miguel Ortiz Berrocal. History To reward the best Spanish films of each year, the Spanish Academy of Motion Pictures and Arts decided to create the Goya Awards. The Goya Awards are Spain's main national film awards, considered by many in Spain, and internation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Golden Globe Award For Best Foreign Language Film
The Golden Globe Award for Best Foreign Language Film is a Golden Globe Award presented by the Hollywood Foreign Press Association. Until 1986, it was known as the Golden Globe Award for Best Foreign Film, meaning that any non-American film could be honoured. In 1987, it was changed to Best Foreign ''Language'' Film, so that non-American English-language films are now considered for the Best Motion Picture awards. Additionally, this change makes American films primarily in another language eligible for this award, including winners like ''Letters from Iwo Jima'' and '' Minari'' as well as nominees such as ''Apocalypto'', ''The Kite Runner'', and ''In the Land of Blood and Honey''. Note that since the 1987 change in the criteria for this award, its eligibility criteria have been considerably broader than those for the Academy Award for Best International Feature Film (known before 2020 as Academy Award for Best Foreign Language Film). American films have never been eligible for th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
65th British Academy Film Awards
The 65th British Academy Film Awards, more commonly known as the BAFTAs, were held on 12 February 2012 at the Royal Opera House in London, honouring the best national and foreign films of 2011. The nominations were announced on 17 January 2012 by actor Daniel Radcliffe and actress Holliday Grainger. Presented by the British Academy of Film and Television Arts, accolades are handed out for the best feature-length film and documentaries of any nationality that were screened at British cinemas in 2011. Stephen Fry, who hosted from 2001 to 2006, returned to host the ceremony. '' The Artist'' won seven awards out of its twelve nominations, including Best Film, Best Director for Michel Hazanavicius, and Best Actor for Jean Dujardin. Meryl Streep won Best Actress for '' The Iron Lady''. Christopher Plummer won Best Supporting Actor for ''Beginners'' and Octavia Spencer won Best Supporting Actress for ''The Help''. ''Tinker Tailor Soldier Spy'', directed by Tomas Alfredson, was voted Outst ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BAFTA Award For Best Film Not In The English Language
The BAFTA Award for Best Film Not in the English Language is given annually by the British Academy of Film and Television Arts and presented at the British Academy Film Awards. The award was first given at the 36th British Academy Film Awards, recognising the films of 1982, and until 1990 was known as the Best Foreign Language Film. Prior to this, films recorded in a language other than English were often recognised in the category BAFTA Award for Best Film, known between 1949 and 1969 as Best Film from any Source, also, in the 1980s there were only European films that the language originally recorded spoken in the film is not English, except '' Ran'', between winners and nominees films in this category. In the following lists, the titles and names in bold with a dark grey background are the winners and recipients respectively; those not in bold are the nominees. The years given are those in which the films under consideration were released, not the year of the ceremony, which alwa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York (magazine)
''New York'' is an American biweekly magazine concerned with life, culture, politics, and style generally, and with a particular emphasis on New York City. Founded by Milton Glaser and Clay Felker in 1968 as a competitor to ''The New Yorker'', it was brasher and less polite, and established itself as a cradle of New Journalism. Over time, it became more national in scope, publishing many noteworthy articles on American culture by writers such as Tom Wolfe, Jimmy Breslin, Nora Ephron, John Heilemann, Frank Rich, and Rebecca Traister. In its 21st-century incarnation under editor-in-chief Adam Moss, "The nation's best and most-imitated city magazine is often not about the city—at least not in the overcrowded, traffic-clogged, five-boroughs sense", wrote then-''Washington Post'' media critic Howard Kurtz, as the magazine increasingly published political and cultural stories of national significance. Since its redesign and relaunch in 2004, the magazine has won more N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tie Me Up! Tie Me Down!
''Tie Me Up! Tie Me Down!'' ( es, link=no, ¡Átame!, , "Tie Me!") is a 1989 Spanish dark romantic comedy film co-written and directed by Pedro Almodóvar, starring Victoria Abril and Antonio Banderas alongside Loles Léon, Francisco Rabal, Julieta Serrano, María Barranco, and Rossy de Palma. The plot follows a recently released psychiatric patient who kidnaps an actress in order to make her fall in love with him. He believes his destiny is to marry her and father her children. The film was highly successful with both critics and audiences in Spain. Its United States release was entangled in controversy, instrumental in the implementation by the MPAA of a new rating category, NC-17, for films of an explicit nature that were previously unfairly regarded as pornographic because of the X rating. Plot Ricky, a 23-year-old psychiatric patient, has been deemed cured and is released from a mental institution. Until then, he has been the lover of the woman director of the hospit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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