The Research Institute At Nationwide Children's Hospital
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The Research Institute At Nationwide Children's Hospital
The Research Institute at Nationwide Children's Hospital is one of America's ten largest free-standing pediatric research centers and works to enhance the health of children by engaging in research. History Origins Research at the Children's Hospital can be traced back to the founding in 1892. Following World War II, extensive resources were dedicated to research, which led to the first successful treatment of histoplasmosis by Dr. Warren Wheeler. Eventually the research conducted at the hospital would be consolidated under C-H-I-L-D, or Children’s Hospital Investigative Laboratory Division. In 1964, Children’s Hospital Research Foundation was founded. In 1998, The Children's Hospital Research Foundation became the Columbus Children's Research Institute. In 2007, following a gift from the Nationwide Foundation, it became The Research Institute at Nationwide Children's Hospital. Medical firsts, breakthroughs, and contributions The first successful treatment of histoplasmosis by ...
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Nationwide Children's Hospital
Nationwide Children's Hospital (formerly Columbus Children's Hospital) is a nationally ranked pediatric acute care teaching hospital located in the Southern Orchards neighborhood of Columbus, Ohio, Columbus, Ohio. The hospital has 673 pediatric beds and is affiliated with the Ohio State University College of Medicine. The hospital provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Ohio and surrounding regions. Nationwide Children's Hospital also sometimes treats adults that require pediatric care. Nationwide Children's Hospital also features an American College of Surgeons, ACS designated Level 1 Trauma Center, Level 1 Pediatric Trauma Center, 1 of 4 in the state. The hospital has affiliations with the nearby Ohio State University Wexner Medical Center. Nationwide Children's Hospital is located on its own campus and has more than 1,379 medical staff members and over 11,909 total employees. In recent y ...
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Columbus, Ohio
Columbus () is the state capital and the most populous city in the U.S. state of Ohio. With a 2020 census population of 905,748, it is the 14th-most populous city in the U.S., the second-most populous city in the Midwest, after Chicago, and the third-most populous state capital. Columbus is the county seat of Franklin County; it also extends into Delaware and Fairfield counties. It is the core city of the Columbus metropolitan area, which encompasses 10 counties in central Ohio. The metropolitan area had a population of 2,138,926 in 2020, making it the largest entirely in Ohio and 32nd-largest in the U.S. Columbus originated as numerous Native American settlements on the banks of the Scioto River. Franklinton, now a city neighborhood, was the first European settlement, laid out in 1797. The city was founded in 1812 at the confluence of the Scioto and Olentangy rivers, and laid out to become the state capital. The city was named for Italian explorer Christopher Columbus. ...
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Histoplasmosis
Histoplasmosis is a fungal infection caused by ''Histoplasma capsulatum''. Symptoms of this infection vary greatly, but the disease affects primarily the lungs. Occasionally, other organs are affected; called disseminated histoplasmosis, it can be fatal if left untreated. Histoplasmosis is common among AIDS patients because of their suppressed immunity. In immunocompetent individuals, past infection results in partial protection against ill effects if reinfected. ''Histoplasma capsulatum'' is found in soil, often associated with decaying bat guano or bird droppings. Disruption of soil from excavation or construction can release infectious elements that are inhaled and settle into the lung. From 1938 to 2013 in the US, 105 outbreaks were reported in a total of 26 states plus Puerto Rico. In 1978 to 1979 during a large urban outbreak in which 100,000 people were exposed to the fungus in Indianapolis, victims had pericarditis, rheumatological syndromes, esophageal and vocal cord ...
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Warren Wheeler
A warren is a network of wild rodent or lagomorph, typically rabbit burrows. Domestic warrens are artificial, enclosed establishment of animal husbandry dedicated to the raising of rabbits for meat and fur. The term evolved from the medieval Anglo-Norman concept of free warren, which had been, essentially, the equivalent of a hunting license for a given woodland. Architecture of the domestic warren The cunicularia of the monasteries may have more closely resembled hutches or pens, than the open enclosures with specialized structures which the domestic warren eventually became. Such an enclosure or ''close'' was called a ''cony-garth'', or sometimes ''conegar'', ''coneygree'' or "bury" (from "burrow"). Moat and pale To keep the rabbits from escaping, domestic warrens were usually provided with a fairly substantive moat, or ditch filled with water. Rabbits generally do not swim and avoid water. A ''pale'', or fence, was provided to exclude predators. Pillow mounds The most c ...
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Nationwide Foundation
Nationwide may refer to: Organisations * Nationwide Building Society, a UK building society * Nationwide Mutual Insurance Company, an insurance company based in Columbus, Ohio, US * Nationwide Asset Services, a debt settlement company in the US * Nationwide Airlines (other), several airlines Sport * Nationwide Series, or Nationwide formerly the Busch Series and now Xfinity Series, was an auto race series sponsored by the Nationwide Mutual Insurance Company * Nationwide Championship, (1991–2000), a golf tournament in Georgia, US * Nationwide Tour (2003–2011), the former name of a second-tier men's golf tour * English Football League, formerly called the Nationwide League * Kenyan Nationwide League, a league below the top tier of Kenyan football TV programmes * ''Nationwide'' (TV programme), a British current affairs series (1969–1983) * ''Nationwide'' (Australian TV programme), a current affairs programme (1979–1984) * ''Nationwide'' (Irish TV programme), a ...
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Samuel Mites
Samuel ''Šəmūʾēl'', Tiberian: ''Šămūʾēl''; ar, شموئيل or صموئيل '; el, Σαμουήλ ''Samouḗl''; la, Samūēl is a figure who, in the narratives of the Hebrew Bible, plays a key role in the transition from the biblical judges to the United Kingdom of Israel under Saul, and again in the monarchy's transition from Saul to David. He is venerated as a prophet in Judaism, Christianity, and Islam. In addition to his role in the Hebrew scriptures, Samuel is mentioned in Jewish rabbinical literature, in the Christian New Testament, and in the second chapter of the Quran (although Islamic texts do not mention him by name). He is also treated in the fifth through seventh books of ''Antiquities of the Jews'', written by the Jewish scholar Josephus in the first century. He is first called "the Seer" in 1 Samuel 9:9. Biblical account Family Samuel's mother was Hannah and his father was Elkanah. Elkanah lived at Ramathaim in the district of Zuph. His genealo ...
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Christopher Walker (physician)
Christopher Walker may refer to: * Christopher J. Walker (1942–2017), British historian * Christopher Walker (athlete) (born 1968), Gibraltarian triathlete and cyclist * Christopher "Kit" Walker, the real name of the comic book character '' The Phantom'' See also * Chris Walker (other) Chris Walker may refer to: *Charles Walker (British politician) (born 1967), also referred to by his nickname Chris *Chris Walker (actor) (born 1964), British actor *Chris Walker (basketball, born 1969), American basketball coach *Chris Walker (bas ...
{{hndis, Walker, Christopher ...
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Robert Castile
The name Robert is an ancient Germanic given name, from Proto-Germanic "fame" and "bright" (''Hrōþiberhtaz''). Compare Old Dutch ''Robrecht'' and Old High German ''Hrodebert'' (a compound of '' Hruod'' ( non, Hróðr) "fame, glory, honour, praise, renown" and ''berht'' "bright, light, shining"). It is the second most frequently used given name of ancient Germanic origin. It is also in use as a surname. Another commonly used form of the name is Rupert. After becoming widely used in Continental Europe it entered England in its Old French form ''Robert'', where an Old English cognate form (''Hrēodbēorht'', ''Hrodberht'', ''Hrēodbēorð'', ''Hrœdbœrð'', ''Hrœdberð'', ''Hrōðberχtŕ'') had existed before the Norman Conquest. The feminine version is Roberta. The Italian, Portuguese, and Spanish form is Roberto. Robert is also a common name in many Germanic languages, including English, German, Dutch, Norwegian, Swedish, Scots, Danish, and Icelandic. It can be u ...
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Exosome Complex
The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of RNA (ribonucleic acid) molecules. Exosome complexes are found in both eukaryotic cells and archaea, while in bacteria a simpler complex called the degradosome carries out similar functions. The core of the exosome contains a six-membered ring structure to which other proteins are attached. In eukaryotic cells, the exosome complex is present in the cytoplasm, nucleus, and especially the nucleolus, although different proteins interact with the exosome complex in these compartments regulating the RNA degradation activity of the complex to substrates specific to these cell compartments. Substrates of the exosome include messenger RNA, ribosomal RNA, and many species of small RNAs. The exosome has an exoribonucleolytic function, meaning it degrades RNA starting at one end (the 3′ end in this case), and in eukaryotes also an endori ...
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National Natural Science Foundation Of China
The National Natural Science Foundation of China (NSFC; ) is an organization directly affiliated to China's State Council for the management of the National Natural Science Fund. History NSFC was founded in February 1986 by theoretical chemist Tang Aoqing, with the approval of the State Council. It is an institution for the management of the National Natural Science Fund, aimed at promoting and financing basic research and applied research in China. In 2010 NSFC launched a medical department, analogous to the United States' National Institutes of Health. Plans for a medical department had been announced in 2001, but only with the 2008 appointment of Chen Zhu as health minister did basic biomedical research gain enough political support to push the department forward. The medical department is expected to give about one billion renminbi in grants for 2010. See also *National Science Foundation The National Science Foundation (NSF) is an independent agency of the United Stat ...
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