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The Hot Zone
''The Hot Zone: A Terrifying True Story'' is a best-selling 1994 nonfiction thriller by Richard Preston about the origins and incidents involving viral hemorrhagic fevers, particularly ebolaviruses and marburgviruses. The basis of the book was Preston's 1992 ''New Yorker'' article "Crisis in the Hot Zone". The filoviruses—including Ebola virus, Sudan virus, Marburg virus, and Ravn virus—are Biosafety Level 4 agents, extremely dangerous to humans because they are very infectious, have a high fatality rate, and most have no known prophylactic measures, treatments, or cures. Along with describing the history of the devastation caused by two of these Central African diseases, Ebola virus disease and Marburg virus disease, Preston described a 1989 incident in which a relative of Ebola virus, Reston virus, was discovered at a primate quarantine facility in Reston, Virginia, less than 15 miles (24 km) away from Washington, D.C. Synopsis The book is in four sections: * "T ...
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Reston, Virginia
Reston is a census-designated place in Fairfax County, Virginia and a principal city of the Washington metropolitan area. As of the 2020 U.S. Census, Reston's population was 63,226. Founded in 1964, Reston was influenced by the Garden City movement that emphasized planned, self-contained communities that intermingled green space, residential neighborhoods, and commercial development. The intent of Reston's founder, Robert E. Simon, was to build a town that would revolutionize post–World War II concepts of land use and residential/corporate development in suburban America. In 2018, Reston was ranked as the Best Place to Live in Virginia by ''Money'' magazine for its expanses of parks, lakes, golf courses, and bridle paths as well as the numerous shopping and dining opportunities in Reston Town Center. History In the early days of Colonial America, the land on which Reston sits was part of the Northern Neck Proprietary, a vast grant by King Charles II to Lord Thomas Fairfax t ...
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Richard Preston
Richard Preston (born August 5, 1954) is a writer for ''The New Yorker'' and bestselling author who has written books about infectious disease, bioterrorism, redwoods and other subjects, as well as fiction. Biography Preston was born in Cambridge, Massachusetts. He graduated Wellesley High School in Massachusetts in 1972 and attended Pomona College in Claremont, California. He earned a Ph.D. in English from Princeton University in 1983. His 1992 ''New Yorker'' article "Crisis in the Hot Zone" was expanded into his breakout book, ''The Hot Zone'' (1994). It is classified as a "non-fiction thriller" about ebolaviruses. He learned of ebola through such contacts as U.S. Army researchers Drs. C.J. Peters and Nancy Jaax. His fascination began during a visit to Africa where he was an eyewitness to epidemics. The book served as the (very loose) basis of the Hollywood movie ''Outbreak'' (1995) about military machinations surrounding a fictional "Motaba virus". Preston's novel '' The ...
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Central Africa
Central Africa is a subregion of the African continent comprising various countries according to different definitions. Angola, Burundi, the Central African Republic, Chad, the Democratic Republic of the Congo, the Republic of the Congo, Equatorial Guinea, Gabon, Rwanda, and São Tomé and Príncipe are members of the Economic Community of Central African States (ECCAS). Six of those states (the Central African Republic, Chad, the Republic of the Congo, Equatorial Guinea, and Gabon) are also members of the Economic and Monetary Community of Central Africa (CEMAC) and share a common currency, the Central African CFA franc. The African Development Bank defines Central Africa as the Central African Republic, Chad, the Democratic Republic of the Congo, the Republic of the Congo, Equatorial Guinea, and Gabon. Middle Africa is an analogous term used by the United Nations in its geoscheme for Africa. It includes the same countries as the African Development Bank's definition, ...
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United States Army Medical Research Institute Of Infectious Diseases
The United States Army Medical Research Institute of Infectious Diseases (USAMRIID; pronounced: you-SAM-rid) is the U.S Army's main institution and facility for defensive research into countermeasures against biological warfare. It is located on Fort Detrick, Maryland, near Washington, D.C. and is a subordinate lab of the U.S. Army Medical Research and Development Command (USAMRDC), headquartered on the same installation. USAMRIID is the only U.S. Department of Defense (DoD) laboratory equipped to study highly hazardous viruses at Biosafety Level 4 within positive pressure personnel suits. USAMRIID employs both military and civilian scientists as well as highly specialized support personnel, totaling around 800 people. In the 1950s and '60s, USAMRIID and its predecessor unit pioneered unique, state-of-the-art biocontainment facilities which it continues to maintain and upgrade. Investigators at its facilities frequently collaborate with the Centers for Disease Control and Pre ...
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Peter Jahrling
Peter B. Jahrling is chief of the Emerging Viral Pathogens Section of the National Institute of Allergy and Infectious Diseases. Jahrling received his PhD in medical microbiology from Cornell Medical College. He joined the military as an officer at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), and remained employed as a civilian after his service. Since 2005, Jahrling has been the chief scientist of the NIAID Integrated Research Facility in Frederick, Maryland, and chief of the Emerging Viral Pathogens Section. His research focuses on the development of animal models for viruses infecting humans, strategies for vaccination and treatment of serious viral pathogens, and characterization of newly discovered viruses. He oversees BSL-4 labs at Fort Detrick. ''The Hot Zone'' mentions Jahrling's early research in Ebola virus. He is portrayed in the first season of The Hot Zone (American TV series), ''The Hot Zone'' television series by Topher Grace. Awards ...
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Centers For Disease Control
The Centers for Disease Control and Prevention (CDC) is the national public health agency of the United States. It is a United States federal agency, under the Department of Health and Human Services, and is headquartered in Atlanta, Georgia. The agency's main goal is the protection of public health and safety through the control and prevention of disease, injury, and disability in the US and worldwide. The CDC focuses national attention on developing and applying disease control and prevention. It especially focuses its attention on infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities designed to improve the health of United States citizens. The CDC also conducts research and provides information on non-infectious diseases, such as obesity and diabetes, and is a founding member of the International Association of National Public Health Institutes.
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