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TGF Beta 1
TGF may refer to: Medicine * Tubuloglomerular feedback, a reflex of the nephrons in the kidney * Transforming growth factor, either of two classes of polypeptide growth factors (TGF-α and TGF-β) Science * Terrestrial gamma-ray flash, a burst of gamma rays produced in the Earth's atmosphere, generally associated with lightning * Tidal Generating Force, an effect of gravity responsible for creating tides * Trivial Graph Format, a text-based file format for describing graphs Entertainment * The Games Factory, video game development software created by Clickteam * The Gracious Few, an American rock group from York, Pennsylvania Other * Chali language The Chali language ( Dzongkha: ཚ་ལི་ཁ་; Wylie: ''Tsha-li-kha''; also called "Chalikha," "Chalipkha," "Tshali," and "Tshalingpa") is an East Bodish language spoken by about 1,398 people in Wangmakhar, Gorsum and Tormazhong villages ..., by ISO 639 code See also

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Tubuloglomerular Feedback
In the physiology of the kidney, tubuloglomerular feedback (TGF) is a feedback system inside the kidneys. Within each nephron, information from the renal tubules (a downstream area of the tubular fluid) is signaled to the glomerulus (an upstream area). Tubuloglomerular feedback is one of several mechanisms the kidney uses to regulate glomerular filtration rate (GFR). It involves the concept of purinergic signaling, in which an increased distal tubular sodium chloride concentration causes a basolateral release of adenosine from the macula densa cells. This initiates a cascade of events that ultimately brings GFR to an appropriate level. Background The kidney maintains the electrolyte concentrations, osmolality, and acid-base balance of blood plasma within the narrow limits that are compatible with effective cellular function; and the kidney participates in blood pressure regulation and in the maintenance of steady whole-organism water volume Fluid flow through the nephron must be ...
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Transforming Growth Factor
Transforming growth factor (, or TGF) is used to describe two classes of polypeptide growth factors, TGFα and TGFβ. The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation. Types * TGFα is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It belongs to the EGF family. * TGFβ exists in three known subtypes in humans, TGFβ1, TGFβ2, and TGFβ3. These are upregulated in Marfan's syndrome and some human cancers, and play crucial roles in tissue regeneration, cell differentiation, embryonic development, and regulation of the immune system. Isoforms of transforming growth factor-beta (TGF-β1) are also thought to be inv ...
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Terrestrial Gamma-ray Flash
A terrestrial gamma-ray flash (TGF), also known as dark lightning, is a burst of gamma rays produced in Earth's atmosphere. TGFs have been recorded to last 0.2 to 3.5 milliseconds, and have energies of up to 20 million electronvolts. It is speculated that TGFs are caused by intense electric fields produced above or inside thunderstorms. Scientists have also detected energetic positrons and electrons produced by terrestrial gamma-ray flashes. Discovery Terrestrial gamma-ray flashes were first discovered in 1994 by BATSE, or Burst and Transient Source Experiment, on the Compton Gamma Ray Observatory, a NASA spacecraft. A subsequent study from Stanford University in 1996 linked a TGF to an individual lightning strike occurring within a few milliseconds of the TGF. BATSE detected only a small number of TGF events in nine years (76), due to it having been constructed to study gamma ray bursts from outer space, which last much longer. In the early 2000s, the Ramaty High Energy ...
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Tidal Force
The tidal force is a gravitational effect that stretches a body along the line towards the center of mass of another body due to a gradient (difference in strength) in gravitational field from the other body; it is responsible for diverse phenomena, including tides, tidal locking, breaking apart of celestial bodies and formation of ring systems within the Roche limit, and in extreme cases, spaghettification of objects. It arises because the gravitational field exerted on one body by another is not constant across its parts: the nearest side is attracted more strongly than the farthest side. It is this difference that causes a body to get stretched. Thus, the tidal force is also known as the differential force, as well as a secondary effect of the gravitational field. In celestial mechanics, the expression ''tidal force'' can refer to a situation in which a body or material (for example, tidal water) is mainly under the gravitational influence of a second body (for example, the Eart ...
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Trivial Graph Format
Trivial Graph Format (TGF) is a simple text-based adjacency list file format for describing graphs, widely used because of its simplicity. Format The format consists of a list of node definitions, which map node IDs to labels, followed by a list of edges, which specify node pairs and an optional edge label. Because of its lack of standardization, the format has many variations. For instance, some implementations of the format require the node IDs to be integers, while others allow more general alphanumeric identifiers. Each node definition is a single line of text starting with the node ID, separated by a space from its label. The node definitions are separated from the edge definitions by a line containing the "#" character. Each edge definition is another line of text, starting with the two IDs for the endpoints of the edge separated by a space. If the edge has a label, it appears on the same line after the endpoint IDs. The graph may be interpreted as a directed or undirected g ...
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The Games Factory
Clickteam is a French software development company based in Boulogne-Billancourt, Hauts-de-Seine. Founded by Francis Poulain, François Lionet and Yves Lamoureux, Clickteam is best known for the creation of Clickteam Fusion, a script-free programming tool that allows users to create video games or other interactive software using a highly advanced event system. History Before co-founding Clickteam, François Lionet was the programmer of STOS BASIC, a programming language released in 1988 for the Atari ST, and AMOS BASIC, a more advanced programming language released in 1990 for the Commodore Amiga. Both of these have since been released in open-source form on the Clickteam corporate website. Yves Lamoureux was also a successful game developer prior to co-founding Clickteam, working with multiple companies on games. Clickteam's debut software was ''Klik & Play'', released in 1994 as commercial, proprietary software; this marked the team's first successful software release. A v ...
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The Gracious Few
The Gracious Few (also known as TGF) were an American rock group from York, Pennsylvania. The band featured guitarist Chad Taylor, bassist Patrick Dahlheimer and drummer Chad Gracey from the band Live, along with lead vocalist Kevin Martin and guitarist Sean Hennesy from the band Candlebox. __TOC__ History Formation With Live on what they initially termed a "two-year hiatus", Taylor, Gracey and Dahlheimer were on a lookout for a vocalist for the new songs they had written. Gracey called his friend Kevin Martin and suggested that he should join them. Martin explained, "He called me and said Pat, Chad, and I have been writing and we think you are the perfect singer for this project.” With Chad Taylor asserting that he no longer wanted to play guitar solos, Martin suggested that his Candlebox bandmate, guitarist Sean Hennesy, could do the job. Hennesy explained, "Tonally, he’s got a big, fat, manly beast sound. I have more of a high-cut karate sound that cuts through, so ...
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