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TCRB
TCRB may refer to: Biology * T-cell receptor beta locus (TCRB, TCRb, TCRđť›˝, Tcrb, Tcrđť›˝), a location on the T-cell receptor * TRCB gene and protein, also known as the T cell receptor beta constant 1 (TCRB1, TRCBC1) * T-cell-rich B-cell lymphoma (TCRB, TCRB-NHL), a type of large-cell lymphoma Other uses * T Coronae Borealis T Coronae Borealis (''T CrB''), is a recurring nova in the constellation Corona Borealis. It was first discovered in outburst in 1866 by John Birmingham, although it had been observed earlier as a 10th magnitude star. Description T CrB ... (T CrB), a recurrent nova variable star system * TCR Benelux Series (TCR-B, TCR-BNL), a racing car championship See also * {{dab ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T-cell Receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR. The TCR is composed of two different protein chains (that is, it is a heterodimer). In humans, in 95% of T cells the TCR consists of an alpha (α) chain and a beta (β) chain (encoded by '' TRA'' and ''TRB'', respectively), whereas in 5% of T cells the TCR consists of gamma and delta (γ/δ) chains (encoded by '' TRG'' and '' TRD'', respectively). This ratio changes during ontogeny and in diseased states (such as leukemia). It also differs between species. Orthologues of the 4 loci have been mapped in various species. Each locus can produce a vari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
