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Tuberculosis Elimination
Tuberculosis elimination is the effort to reduce the number of tuberculosis (TB) cases to less than one per 1 million population, contrasted with the effort to completely eradicate infection in humans worldwide. The goal of tuberculosis elimination is hampered by the lack of rapid testing, short and effective treatment courses, and completely effective vaccine. The WHO as well as the Stop TB Partnership aim for the full elimination of TB by 2050—requiring a 1000-fold reduction in tuberculosis incidence. As of 2017, tuberculosis has not been eliminated from any country. Feasibility Tuberculosis has been a curable illness since the 1940s when the first drugs became available, although multidrug-resistant and extensively drug-resistant TB present an increasing challenge. According to a 2017 article in ''International Journal of Infectious Diseases'', tuberculosis eradication is possible if enough technology, funding, and political will were available, but the characteristics of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is spread from one person to the next through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people with HIV/AIDS and in those who smoke. Diagnosis of active TB is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eradication Of Infectious Diseases
Eradication is the reduction of an infectious disease's prevalence in the global host population to zero. Two infectious diseases have successfully been eradicated: smallpox in humans, and rinderpest in ruminants. There are four ongoing programs, targeting the human diseases poliomyelitis (polio), yaws, dracunculiasis (Guinea worm), and malaria. Five more infectious diseases have been identified as potentially eradicable with current technology by the Carter Center International Task Force for Disease Eradication— measles, mumps, rubella, lymphatic filariasis (elephantiasis) and cysticercosis (pork tapeworm). The concept of disease eradication is sometimes confused with disease ''elimination'', which is the reduction of an infectious disease's prevalence in a regional population to zero, or the reduction of the global prevalence to a negligible amount. Further confusion arises from the use of the term 'eradication' to refer to the total removal of a given pathogen from an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculosis Vaccine
Tuberculosis (TB) vaccines are vaccinations intended for the prevention of tuberculosis. Immunotherapy as a defence against TB was first proposed in 1890 by Robert Koch.Prabowo, S. et al. "Targeting multidrug-resistant tuberculosis (MDR-TB) by therapeutic vaccines." Med Microbiol Immunol 202 (2013): 95–1041. Print. Today, the only effective tuberculosis vaccine in common use is the Bacillus Calmette-Guérin (BCG) vaccine, first used on humans in 1921.White, A. et al. "Evaluation of the Safety and Immunogenicity of a Candidate Tuberculosis Vaccine, MVA85A, Delivered by Aerosol to the Lungs of Macaques." Clinical and Vaccine Immunology 20 (2013): 663–672. Print. About three out of every 10,000 people who get the vaccine experience side effects, which are usually minor except in severely immuno-depressed individuals. While BCG immunization provides fairly effective protection for infants and young children (including defence against TB meningitis and miliary TB),Hussey, G, T Haw ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stop TB Partnership
The Stop TB Partnership was established in 2001 to eliminate tuberculosis as a public health problem. Its 1500 partner organizations include international, nongovernmental and governmental organizations and patient groups. The secretariat is based in Geneva, Switzerland, and, since 2015, has been administered by UNOPS. Previously it was hosted by the World Health Organization. History The Stop TB Initiative was established following the meeting of the First Session of the Ad Hoc Committee on the Tuberculosis Epidemic held in London in March 1998. In March 2000 the Stop TB Partnership produced the Amsterdam Declaration to Stop TB, which called for action from ministerial delegations of 20 countries with the highest burden of TB. That same year the World Health Assembly endorsed the establishment of a Global Partnership to Stop TB. Global Plan to End Tuberculosis The Global Plan 2016-2020 is a 5-year investment plan that represents the roadmap to accelerating impact on the TB epide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prospects For Tuberculosis Control And Elimination
Prospect may refer to: General * Prospect (marketing), a marketing term describing a potential customer * Prospect (sports), any player whose rights are owned by a professional team, but who has yet to play a game for the team * Prospect (mining), a particular geological area on which searching for minerals or fossils is commonly carried out Arts, entertainment, and media Periodicals * ''Prospect'' (architecture magazine), a Scottish architecture magazine * ''Prospect'' (magazine), a monthly British essay and comment magazine * ''The American Prospect'', an American quarterly policy magazine Other uses in arts, entertainment, and media * ''Prospect'' (film), 2018 American science fiction film starring Sophie Thatcher, Jay Duplass, and Pedro Pascal * Prospect (rapper), a New York City rapper who collaborates with Full a Clips Crew and former member of Terror Squad * Prospect (Slovenian band), a progressive metal band from Ljubljana, Slovenia * Prospects (TV series), Britis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multidrug-resistant Tuberculosis
Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis (TB) infection caused by bacteria that are resistant to treatment with at least two of the most powerful first-line anti-TB medications (drugs): isoniazid and rifampin. Some forms of TB are also resistant to second-line medications, and are called extensively drug-resistant TB ( XDR-TB). Tuberculosis is caused by infection with the bacterium ''Mycobacterium tuberculosis''. Almost one in four people in the world are infected with TB bacteria. Only when the bacteria become active do people become ill with TB. Bacteria become active as a result of anything that can reduce the person's immunity, such as HIV, advancing age, diabetes or other immunocompromising illnesses. TB can usually be treated with a course of four standard, or first-line, anti-TB drugs (i.e., isoniazid, rifampin, pyrazinamide and ethambutol). However, beginning with the first antibiotic treatment for TB in 1943, some strains of the TB bacteri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Extensively Drug-resistant Tuberculosis
Extensively drug-resistant tuberculosis (XDR-TB) is a form of tuberculosis caused by bacteria that are resistant to some of the most effective anti-TB drugs. XDR-TB strains have arisen after the mismanagement of individuals with multidrug-resistant TB (MDR-TB). Almost one in four people in the world is infected with TB bacteria. Only when the bacteria become active do people become ill with TB. Bacteria become active as a result of anything that can reduce the person's immunity, such as HIV, advancing age, or some medical conditions. TB can usually be treated with a course of four standard, or first-line, anti-TB drugs (i.e., isoniazid, rifampin and any fluoroquinolone). If these drugs are misused or mismanaged, multidrug-resistant TB (MDR-TB) can develop. MDR-TB takes longer to treat with second-line drugs (i.e., amikacin, kanamycin, or capreomycin), which are more expensive and have more side-effects. XDR-TB can develop when these second-line drugs are also misused or mismana ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Journal Of Infectious Diseases
The International Society for Infectious Diseases (ISID), established in 1986, is a nonprofit organization that monitors infectious diseases on a global scale. It also offers grants and fellowships, publishes a journal, and runs online learning platforms for sharing information on managing infectious diseases. It is based in Brookline, Massachusetts, USA. The organization solicits donations from the general public, as well as governments, foundations, and the pharmaceutical industry. Work Society recognizes the evolving nature of infectious diseases and their ability to cross regional and national boundaries. Through training and educational opportunities for healthcare professionals, society works to overcome these obstacles to improve health on a global scale. ISID seeks to establish lasting partnerships with all manner of health-related disciplines to develop innovative methods for infectious disease control. With programs such as ProMED-mail, the International Congress on Infec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Political Will
Political will is defined as "the extent of committed support among key decision makers for a particular policy solution to a particular problem." It is also considered by political scientist Linn Hammergren to be "the slipperiest concept in the policy lexicon." Lack of political will is often blamed for unresolved political issues. References {{reflist Politics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Latent Tuberculosis
Latent tuberculosis (LTB), also called latent tuberculosis infection (LTBI) is when a person is infected with ''Mycobacterium tuberculosis'', but does not have active tuberculosis. Active tuberculosis can be contagious while latent tuberculosis is not, and it is therefore not possible to get TB from someone with latent tuberculosis. The main risk is that approximately 10% of these people (5% in the first two years after infection and 0.1% per year thereafter) will go on to develop active tuberculosis. This is particularly true, and there is added risk, in particular situations such as medication that suppresses the immune system or advancing age. The identification and treatment of people with latent TB is an important part of controlling this disease. Various treatment regimens are in use for latent tuberculosis. They generally need to be taken for several months. Transmission Latent disease ''"TB Bacteria Are Spread Only from a Person with Active TB Disease ... In people ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Active Tuberculosis
Tuberculosis (TB) is an infectious disease usually caused by ''Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. Around 10% of latent infections progress to active disease which, if left untreated, kill about half of those affected. Typical symptoms of active TB are chronic cough with hemoptysis, blood-containing sputum, mucus, fever, night sweats, and weight loss. It was historically referred to as consumption due to the weight loss associated with the disease. Infection of other organs can cause a wide range of symptoms. Tuberculosis is Human-to-human transmission, spread from one person to the next Airborne disease, through the air when people who have active TB in their lungs cough, spit, speak, or sneeze. People with Latent TB do not spread the disease. Active infection occurs more often in people wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World Health Organization
The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of health". Headquartered in Geneva, Switzerland, it has six regional offices and 150 field offices worldwide. The WHO was established on 7 April 1948. The first meeting of the World Health Assembly (WHA), the agency's governing body, took place on 24 July of that year. The WHO incorporated the assets, personnel, and duties of the League of Nations' Health Organization and the , including the International Classification of Diseases (ICD). Its work began in earnest in 1951 after a significant infusion of financial and technical resources. The WHO's mandate seeks and includes: working worldwide to promote health, keeping the world safe, and serve the vulnerable. It advocates that a billion more people should have: universal health care coverag ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
