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Trypanosoma Brucei
''Trypanosoma brucei'' is a species of parasitic Kinetoplastida, kinetoplastid belonging to the genus ''Trypanosoma'' that is present in sub-Saharan Africa. Unlike other protozoan parasites that normally infect blood and tissue cells, it is exclusively extracellular and inhabits the blood plasma and body fluids. It causes deadly vector-borne diseases: African trypanosomiasis or sleeping sickness in humans, and animal trypanosomiasis or ''nagana'' in cattle and horses. It is a species complex grouped into three subspecies: ''T. b. brucei'', ''T. b. gambiense'' and ''T. b. rhodesiense''. The first is a parasite of non-human mammals and causes ''nagana'', while the latter two are zoonotic infecting both humans and animals and cause African trpanosomiasis. ''T. brucei'' is transmitted between mammal hosts by an insect Vector (epidemiology), vector belonging to different species of tsetse fly (''Glossina''). Transmission occurs by biting during the insect's blood meal. The parasites un ...
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Phase-contrast
__NOTOC__ Phase-contrast microscopy (PCM) is an optical microscopy technique that converts phase shifts in light passing through a transparent specimen to brightness changes in the image. Phase shifts themselves are invisible, but become visible when shown as brightness variations. When light waves travel through a medium other than a vacuum, interaction with the medium causes the wave amplitude and phase (waves), phase to change in a manner dependent on properties of the medium. Changes in amplitude (brightness) arise from the scattering and absorption of light, which is often wavelength-dependent and may give rise to colors. Photographic equipment and the human eye are only sensitive to amplitude variations. Without special arrangements, phase changes are therefore invisible. Yet, phase changes often convey important information. Phase-contrast microscopy is particularly important in biology. It reveals many cell (biology), cellular structures that are invisible with a brigh ...
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Trypanosoma Equiperdum
''Τrypanosoma equiperdum'' is a species of kinetoplastid parasites that causes Dourine or covering sickness in horses and other animals in the family equidae. ''T. equiperdum'' is the only trypanosome that is not spread by an insect vector. There has been substantial controversy surrounding whether ''T. equiperdum'' should be considered a unique species, or a strain of '' T. evansi'' or '' T. brucei''. ''T. equiperdum'' is unique in that its kinetoplast, the network of connected rings that make up its mitochondrial DNA Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial D ..., consists of thousands of "minicircles" that are identical in sequence. References External links * Parasites of equines Parasitic excavates Trypanosomatida {{Excavata-stub ja:媾疫トリパノソー ...
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Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ...
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John Rose Bradford
Sir John Rose Bradford, 1st Baronet (7 May 1863 – 7 April 1935) was a British physician. Early life John Rose Bradford was born in London, the son of Abraham Rose and Ellen (née Ltttleton) Bradford. His father was a Deputy Inspector-General of Hospitals in the Royal Navy. He was educated at University College School and in Bruges, before studying for a degree at University College and qualifying as a doctor in 1883. Career After serving as a house physician in University College Hospital he was made an Assistant Physician in 1889 and then moved to hold the same position at the National Hospital for the Paralysed and Epileptic from 1893 to 1896. His main interest was physiological research on such subjects as the electrical phenomena accompanying secretion, the action of drugs on the circulation and secretion of the kidney, and the innervation of various blood vessels. In 1894 he was elected a Fellow of the Royal Society and in 1898 published ''Clinical Lectures on Nephrit ...
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Lebombo Mountains
The Lebombo Mountains, also called Lubombo Mountains ( pt, Montes Libombos), are an , narrow range of mountains in Southern Africa. They stretch from Hluhluwe in KwaZulu-Natal in the south to Punda Maria in the Limpopo Province in South Africa in the north. Parts of the mountain range are also found in Mozambique and Eswatini. Description Geologically, the range is considered a monocline; part of a rifted volcanic margin. The Lebombo monocline was aligned with the Explora Escarpment off-shore Dronning Maud Land, Antarctica, before the break-up of Gondwana. The Lebombo monocline strikes N-S and dips to the east. It is composed of a sequence of Jurassic age volcanic rock, both basaltic lavas and rhyolitic flows and tuffs. The sequence rests on essentially horizontal Karoo Supergroup sedimentary rocks of the Kalahari Craton to the west and is overlain by Cretaceous to recent sediments to the east. The alternating resistant rhyolite and easily eroded basalts produce a series of para ...
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Netley Hospital
The Royal Victoria Hospital or Netley Hospital was a large military hospital in Netley, near Southampton, Hampshire, England. Construction started in 1856 at the suggestion of Queen Victoria but its design caused some controversy, chiefly from Florence Nightingale. Often visited by Queen Victoria, the hospital was extensively used during the First World War. It became the 28th US General Hospital during the invasion of mainland Europe in the Second World War.Spike Island. Philip Hoare. . The main building – the world's longest building when it was completed – was entirely demolished in 1966, except for the chapel and former YMCA building, which still survive. The extensive outbuildings, which once occupied a vast acreage of land to the rear of the main building, finally succumbed in 1978. The site of the hospital can be seen and explored in Royal Victoria Country Park. The hospital was situated within the larger area of land bounded by the River Itchen and River Hamble, par ...
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Royal Army Medical Corps
The Royal Army Medical Corps (RAMC) is a specialist corps in the British Army which provides medical services to all Army personnel and their families, in war and in peace. The RAMC, the Royal Army Veterinary Corps, the Royal Army Dental Corps and Queen Alexandra's Royal Army Nursing Corps form the Army Medical Services. History Origins Medical services in the British armed services date from the formation of the Standing Regular Army after the Restoration of Charles II in 1660. Prior to this, from as early as the 13th century there are records of surgeons and physicians being appointed by the English army to attend in times of war; but this was the first time a career was provided for a Medical Officer (MO), both in peacetime and in war. For much of the next two hundred years, army medical provision was mostly arranged on a regimental basis, with each battalion arranging its own hospital facilities and medical supplies. An element of oversight was provided by the appointment ...
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Thomas Masterman Winterbottom
Dr. Thomas Masterman Winterbottom (26 March 1766, in South Shields – 8 July 1859) was an English physician, philanthropist and abolitionist remembered for describing African trypanosomiasis and the associated Winterbottom's sign. Biography Thomas Winterbottom was the eldest son of Dr. James Winterbottom, a surgeon-apothecary, and Lydia née Masterman, and was educated by the local Curate. He studied medicine at the University of Edinburgh and then the University of Glasgow. He was appointed physician to the colony of the Sierra Leone Company in 1792, spending 4 years in Africa. During this period he accepted John Macaulay Wilson into his household. Wilson went on to become one of the first European trained African medical staff in Africa. In 1793, Winterbottom became one of the founder members of the Newcastle Literary and Philosophical Society. In 1796 he returned to South Tyneside to take over his father's practice in South Shields. He wrote an account of his time in Afri ...
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An Inhabitant Of Buruma Island, Uganda, Suffering From Sleep Wellcome V0029100
An, AN, aN, or an may refer to: Businesses and organizations * Airlinair (IATA airline code AN) * Alleanza Nazionale, a former political party in Italy * AnimeNEXT, an annual anime convention located in New Jersey * Anime North, a Canadian anime convention * Ansett Australia, a major Australian airline group that is now defunct (IATA designator AN) * Apalachicola Northern Railroad (reporting mark AN) 1903–2002 ** AN Railway, a successor company, 2002– * Aryan Nations, a white supremacist religious organization * Australian National Railways Commission, an Australian rail operator from 1975 until 1987 * Antonov, a Ukrainian (formerly Soviet) aircraft manufacturing and services company, as a model prefix Entertainment and media * Antv, an Indonesian television network * ''Astronomische Nachrichten'', or ''Astronomical Notes'', an international astronomy journal * ''Avisa Nordland'', a Norwegian newspaper * ''Sweet Bean'' (あん), a 2015 Japanese film also known as ''An'' ...
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Zulu Language
Zulu (), or isiZulu as an endonym, is a Southern Bantu language of the Nguni branch spoken in Southern Africa. It is the language of the Zulu people, with about 12 million native speakers, who primarily inhabit the province of KwaZulu-Natal of South Africa. Zulu is the most widely spoken home language in South Africa (24% of the population), and it is understood by over 50% of its population. It became one of South Africa's 11 official languages in 1994. According to Ethnologue, it is the second-most-widely spoken of the Bantu languages, after Swahili. Like many other Bantu languages, it is written with the Latin alphabet. In South African English, the language is often referred to in its native form, ''isiZulu''. Geographical distribution Zulu migrant populations have taken it to adjacent regions, especially Zimbabwe, where the Northern Ndebele language ( isiNdebele) is closely related to Zulu. Xhosa, the predominant language in the Eastern Cape, is often considered ...
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Nagana
Animal trypanosomiasis, also known as nagana and nagana pest, or sleeping sickness, is a disease of vertebrates. The disease is caused by trypanosomes of several species in the genus ''Trypanosoma'' such as ''Trypanosoma brucei''. ''Trypanosoma vivax'' causes nagana mainly in West Africa, although it has spread to South America. The trypanosomes infect the blood of the vertebrate host, causing fever, weakness, and lethargy, which lead to weight loss and anemia; in some animals the disease is fatal unless treated. The trypanosomes are transmitted by tsetse flies. An interesting feature is the remarkable tolerance to nagana pathology shown by some breeds of cattle, notably the N'Dama – a West African ''Bos taurus'' breed. This contrasts with the susceptibility shown by East African '' Bos indicus'' cattle such as the zebu. Transmission Most trypanosomes develop in tsetse flies (''Glossina'' spp.), its biological vector, in about one to a few weeks. When an infected tsetse fly b ...
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Zulu Kingdom
The Zulu Kingdom (, ), sometimes referred to as the Zulu Empire or the Kingdom of Zululand, was a monarchy in Southern Africa. During the 1810s, Shaka established a modern standing army that consolidated rival clans and built a large following which ruled a wide expanse of Southern Africa that extended along the coast of the Indian Ocean from the Tugela River in the south to the Pongola River in the north. A bitter civil war in the mid-19th century erupted which culminated in the 1859 Battle of Ndondakusuka between the brothers Cetshwayo and Mbuyazi. In 1879, a British force invaded Zululand, beginning the Anglo-Zulu War. After an initial Zulu victory at the Battle of Isandlwana in January, the British regrouped and defeated the Zulus in July during the Battle of Ulundi, ending the war. The area was absorbed into the Colony of Natal and later became part of the Union of South Africa. History Rise under Shaka Shaka was the illegitimate son of Senzangakhona, Chief of the ...
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