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Trichobilharzia Regenti
''Trichobilharzia regenti'' is a neuropathogenic parasitic flatworm of birds which also causes cercarial dermatitis in humans. The species was originally described in 1998 in the Czech Republic and afterwards it was detected also in other European countries, e.g. Denmark, Germany, France, Iceland, Poland, Switzerland, or Russia, and even in Iran. For its unique neurotropic behaviour in vertebrate hosts, the host-parasite interactions are extensively studied in terms of molecular biology, biochemistry and immunology. Life cycle The life cycle of ''T. regenti'' is analogous to that of human schistosomes. Adult flukes mate in a nasal mucosa of anatid birds (e.g. ''Anas platyrhynchos, Spatula clypeata'' or ''Cairina moschata'') and produce eggs with miracidia which hatch directly in the host tissue and leak outside when the bird is drinking/feeding. Once in water, the miracidia swim using their cilia and actively search for a proper molluscan intermediate host (''Radix lagotis, Rad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flatworm
The flatworms, flat worms, Platyhelminthes, or platyhelminths (from the Greek πλατύ, ''platy'', meaning "flat" and ἕλμινς (root: ἑλμινθ-), ''helminth-'', meaning "worm") are a phylum of relatively simple bilaterian, unsegmented, soft-bodied invertebrates. Unlike other bilaterians, they are acoelomates (having no body cavity), and have no specialized circulatory and respiratory organ (anatomy), organs, which restricts them to having flattened shapes that allow oxygen and nutrients to pass through their bodies by diffusion. The digestive cavity has only one opening for both ingestion (intake of nutrients) and egestion (removal of undigested wastes); as a result, the food cannot be processed continuously. In traditional medicinal texts, Platyhelminthes are divided into Turbellaria, which are mostly non-parasitic animals such as planarians, and three entirely parasitic groups: Cestoda, Trematoda and Monogenea; however, since the turbellarians have since been prove ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cilia
The cilium, plural cilia (), is a membrane-bound organelle found on most types of eukaryotic cell, and certain microorganisms known as ciliates. Cilia are absent in bacteria and archaea. The cilium has the shape of a slender threadlike projection that extends from the surface of the much larger cell body. Eukaryotic flagella found on sperm cells and many protozoans have a similar structure to motile cilia that enables swimming through liquids; they are longer than cilia and have a different undulating motion. There are two major classes of cilia: ''motile'' and ''non-motile'' cilia, each with a subtype, giving four types in all. A cell will typically have one primary cilium or many motile cilia. The structure of the cilium core called the axoneme determines the cilium class. Most motile cilia have a central pair of single microtubules surrounded by nine pairs of double microtubules called a 9+2 axoneme. Most non-motile cilia have a 9+0 axoneme that lacks the central pair of mi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BALB/c
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation. History The founding animals of the strain were obtained by Halsey J. Bagg of Memorial Hospital, New York, from a mouse dealer in Ohio in 1913. The name BALB is a concatenation of Bagg and Albino. From 1920, the progeny of the original colony were systematically inbred, sibling to sibling, for 26 generations over 15 years. During this time, the colony passed through the care of a number of scientists, including C.C. Little and E.C. MacDowell at the Carnegie Institution of Washington and H.J. Muller at the University of Texas at Austin.Potter M. History of the BALB/c family, pp 1-5. In: The BALB/c Mouse: Genetics and Immunology, ''Current Topics in Microbiology and Immunology'', Vol. 122. Springer- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
C57BL/6
C57BL/6, often referred to as "C57 black 6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain, due to the availability of congenic strains, easy breeding, and robustness. Origin The inbred strain of C57BL mice was created in 1921 by C. C. Little at the Bussey Institute for Research in Applied Biology. The substrain "6" was the most popular of the surviving substrains. Little's supervisor William E. Castle had obtained the predecessor strain of C57BL/6, "mouse number 57", from Abbie Lathrop who was breeding inbred strains for mammary tumor research in collaboration with Leo Loeb at the time. Appearance and behavior C57BL/6 mice have a dark brown, nearly black coat. They are more sensitive to noise and odours and are more likely to bite than the more docile laboratory strains such as BA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Domestic Duck
The domestic duck or domestic mallard (''Anas platyrhynchos domesticus'') is a subspecies of mallard that has been domesticated by humans and raised for meat, eggs, and down feathers. A few are also kept for show, as pets, or for their ornamental value. Almost all varieties of domesticated ducks, apart from the domestic Muscovy duck (''Cairina moschata''), are descended from the mallard. Domestication Whole-genome sequencing indicate that domestic ducks originate from a single domestication event of mallards during the Neolithic, followed by rapid selection for lineages favoring meat or egg production. They were likely domesticated in Southeast Asia (most likely Southern China) by the rice paddy-farming ancestors of modern Southeast Asians. The date of domestication is unknown due to the scarcity of archaeological records. They spread outwards from the region, first being mentioned in Han Chinese written records in central China by around 500 BC. Duck farming for both meat an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Swimmer's Itch
Swimmer's itch, cercarial dermatitis or schistosome dermatitis is a short-term allergic contact dermatitis occurring in the skin of humans that have been infected by water-borne schistosomes, a type of flatworm. It is common in freshwater, brackish and marine habitats worldwide. The incidence of this condition may be increasing, although this may be attributed to better monitoring and reporting. Nevertheless, the condition is considered to be an emerging infectious disease. The main symptom is itchy papules (raised skin) that commonly occur within 2 days of infection. Initially, wheals develop quickly, then turn into maculae in about half an hour. Within 10–12 hours these turn into very itchy papules that reach their worst by the second or third day. The papules disappear in 1–2 weeks but secondary effects from scratching can continue longer. The intense itching, which peaks after 48–72 hours, is associated with pain and swelling of the affected areas. People repeatedly expo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Schistosomula
''Schistosoma'' is a genus of trematodes, commonly known as blood flukes. They are parasitic flatworms responsible for a highly significant group of infections in humans termed ''schistosomiasis'', which is considered by the World Health Organization as the second-most socioeconomically devastating parasitic disease (after malaria), with hundreds of millions infected worldwide. Adult flatworms parasitize blood capillaries of either the mesenteries or plexus of the bladder, depending on the infecting species. They are unique among trematodes and any other flatworms in that they are dioecious with distinct sexual dimorphism between male and female. Thousands of eggs are released and reach either the bladder or the intestine (according to the infecting species), and these are then excreted in urine or feces to fresh water. Larvae must then pass through an intermediate snail host, before the next larval stage of the parasite emerges that can infect a new mammalian host ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Glycocalyx
The glycocalyx, also known as the pericellular matrix, is a glycoprotein and glycolipid covering that surrounds the cell membranes of bacteria, epithelial cells, and other cells. In 1970, Martinez-Palomo discovered the cell coating in animal cells, which is known as the glycocalyx. Animal epithelial cells have a fuzz-like coating on the external surface of their plasma membranes. This viscous coating consists of several carbohydrate moieties of membrane glycolipids and glycoproteins, which serve as backbone molecules for support. Generally, the carbohydrate portion of the glycolipids found on the surface of plasma membranes helps these molecules contribute to cell–cell recognition, communication, and intercellular adhesion. The glycocalyx is a type of identifier that the body uses to distinguish between its own healthy cells and transplanted tissues, diseased cells, or invading organisms. Included in the glycocalyx are cell-adhesion molecules that enable cells to adhere to eac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cercaria
A cercaria (plural cercariae) is the larval form of the trematode class of parasites. It develops within the germinal cells of the sporocyst or redia. A cercaria has a tapering head with large penetration glands. It may or may not have a long swimming "tail", depending on the species. The motile cercaria finds and settles in a host where it will become either an adult, or a mesocercaria, or a metacercaria, according to species. Rotifers (''Rotaria Rotaria is a genus of asexual, microscopic animal known as a bdelloid rotifer. Analysis published in 2007 of morphology and DNA sequence data of species form the genus confirmed that despite their asexual mechanism of reproduction, two fundame ... rotatoria'') produce a chemical, Schistosome Paralysis Factor, suppressing cercaria swimming and reducing infections.{{cite journal , editor1-last=Khosla , editor1-first=Chaitan , last1=Gao, first1=Jiarong, last2=Yang, first2=Ning, last3=Lewis, first3=Fred A., last4=Yau, first4=Peter, la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trematode Life Cycle Stages
Trematodes are parasitic flatworms of the class ''Trematoda'', specifically parasitic flukes with two suckers: one ventral and the other oral. Trematodes are covered by a tegument, that protects the organism from the environment by providing secretory and absorptive functions. The life cycle of a typical trematode begins with an egg. Some trematode eggs hatch directly in the environment (water), while others are eaten and hatched within a host, typically a mollusc. The hatchling is called a ''miracidium,'' a free-swimming, ciliated larva. Miracidia will then grow and develop within the intermediate host into a sac-like structure known as a sporocyst or into rediae, either of which may give rise to free-swimming, motile cercariae larvae. The cercariae then could either infect a vertebrate host or a second intermediate host. Adult metacercariae or mesocercariae, depending on the individual trematode's life cycle, will then infect the vertebrate host or be rejected and excreted thro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radix Peregra
''Peregriana peregra'' is a species of air-breathing freshwater snail, an aquatic pulmonate gastropod in the family Lymnaeidae, the pond snails. Distribution and habitat This small pond snail is found in Europe, Newfoundland and northern Asia. This species is common in slow-moving or still water.Janus Horst. (1965). ''The young specialist looks at land and freshwater molluscs''. Burke, London. References External links''Radix peregra'' at Animalbase AnimalBase is a project brought to life in 2004 and is maintained by the University of Göttingen, Germany. The goal of the AnimalBase project is to digitize early zoological literature, provide copyright-free open access to zoological works, and pr ... Lymnaeidae Gastropods described in 1774 Taxa named by Otto Friedrich Müller {{Lymnaeidae-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radix Labiata
''Peregriana peregra'' is a species of air-breathing freshwater snail, an aquatic pulmonate gastropod in the family Lymnaeidae, the pond snails. Distribution and habitat This small pond snail is found in Europe, Newfoundland and northern Asia. This species is common in slow-moving or still water.Janus Horst. (1965). ''The young specialist looks at land and freshwater molluscs''. Burke, London. References External links''Radix peregra'' at Animalbase AnimalBase is a project brought to life in 2004 and is maintained by the University of Göttingen, Germany. The goal of the AnimalBase project is to digitize early zoological literature, provide copyright-free open access to zoological works, and pr ... Lymnaeidae Gastropods described in 1774 Taxa named by Otto Friedrich Müller {{Lymnaeidae-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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