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Tony Nicklinson
This is a list of notable people with locked-in syndrome, a syndrome where a patient is Consciousness, conscious and Self-awareness, self-aware but is completely Paralysis, paralyzed. Gil Avni Israeli citizen Gil Avni, then 33, experienced ''complete locked-in syndrome'' (CLIS) at Meir Hospital, Kfar Saba, Kefar Sava, Israel, after experiencing an unknown health impacting incident at his home while watching TV. When Avni's wife, Orit, a nurse, arrived home, she found him bearing a pulse rate of about 160, making 50 breathes per minute, with symptoms of cyanosis, and called an ambulance. During transport, a dangerously low Oxygen saturation (medicine), oxygen saturation of 50% was detected. When reaching the hospital, Avni was anesthetized and ventilated, later (after CT scan, CT) diagnosed with cerebral edema. Avni, since arriving at the hospital, consciously experienced and remembered most if not all of his surroundings audio-visually, later auditory (with eye lids closed), incl ...
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Locked-in Syndrome
Locked-in syndrome (LIS), also known as pseudocoma, is a condition in which a patient is aware but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles in the body except for vertical eye movements and blinking. The individual is conscious and sufficiently intact cognitively to be able to communicate with eye movements. Electroencephalography results are normal in locked-in syndrome. Total locked-in syndrome, or completely locked-in state (CLIS), is a version of locked-in syndrome wherein the eyes are paralyzed as well. Fred Plum and Jerome B. Posner coined the term for this disorder in 1966. Signs and symptoms Locked-in syndrome is usually characterized by quadriplegia (loss of limb function) and the inability to speak in otherwise cognitively intact individuals. Those with locked-in syndrome may be able to communicate with others through coded messages by blinking or moving their eyes, which are often not affected by the paralysis. The ...
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France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ...
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High Court Of Justice
The High Court of Justice in London, known properly as His Majesty's High Court of Justice in England, together with the Court of Appeal of England and Wales, Court of Appeal and the Crown Court, are the Courts of England and Wales, Senior Courts of England and Wales. Its name is abbreviated as EWHC (England and Wales High Court) for legal citation purposes. The High Court deals at Court of first instance, first instance with all high value and high importance Civil law (common law), civil law (non-criminal law, criminal) cases; it also has a supervisory jurisdiction over all subordinate courts and tribunals, with a few statutory exceptions, though there are debates as to whether these exceptions are effective. The High Court consists of three divisions: the King's Bench Division, the #Chancery Division, Chancery Division and the #Family Division, Family Division. Their jurisdictions overlap in some cases, and cases started in one division may be transferred by court order to ...
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BMC Neurology
BioMed Central (BMC) is a United Kingdom-based, for-profit scientific open access publisher that produces over 250 scientific journals. All its journals are published online only. BioMed Central describes itself as the first and largest open access science publisher. It was founded in 2000 and has been owned by Springer, now Springer Nature, since 2008. History BioMed Central was founded in 2000 as part of the Current Science Group (now Science Navigation Group, SNG), a nursery of scientific publishing companies. SNG chairman Vitek Tracz developed the concept for the company after NIH director Harold Varmus's PubMed Central concept for open-access publishing was scaled back. The first director of the company was Jan Velterop. Chemistry Central was established in 2006 and the PhysMath Central journal imprint in 2007. In 2002, the company introduced article processing charges, and these have since been the primary source of revenue. In 2007 Yale University Libraries stopped su ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and oth ...
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Der Spiegel
''Der Spiegel'' (, lit. ''"The Mirror"'') is a German weekly news magazine published in Hamburg. With a weekly circulation of 695,100 copies, it was the largest such publication in Europe in 2011. It was founded in 1947 by John Seymour Chaloner, a British army officer, and Rudolf Augstein, a former Wehrmacht radio operator who was recognized in 2000 by the International Press Institute as one of the fifty World Press Freedom Heroes. Typically, the magazine has a content to advertising ratio of 2:1. ''Der Spiegel'' is known in German-speaking countries mostly for its investigative journalism. It has played a key role in uncovering many political scandals such as the ''Spiegel'' affair in 1962 and the Flick affair in the 1980s. According to ''The Economist'', ''Der Spiegel'' is one of continental Europe's most influential magazines. The news website by the same name was launched in 1994 under the name ''Spiegel Online'' with an independent editorial staff. Today, the content is ...
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Steven Laureys
Steven Laureys (born 24 December 1968 in Leuven) is a Belgian neurologist. He is principally known as a clinician and researcher in the field of neurology of consciousness. Career Prof. Laureys graduated as a Medical Doctor from the Vrije Universiteit Brussel, Belgium, in 1993. While specializing in neurology he entered a research career and obtained his MSc in Pharmaceutical Medicine working on pain and stroke using in vivo microdialysis and diffusion MRI in the rat (1997). Drawn by functional neuroimaging, he moved to thCyclotron Research Centerat the University of Liège, Belgium, where he obtained his PhD studying residual brain function in the vegetative state in 2000. He is board-certified in neurology (1998) and in end-of-life and palliative medicine (2004). He currently leads thComa Science Groupat thof the University of Liège, Belgium. He is clinical professor of neurology, at thLiège University Hospitaland Research Director at the National Fund for Scientific Research ...
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The Huffington Post
''HuffPost'' (formerly ''The Huffington Post'' until 2017 and sometimes abbreviated ''HuffPo'') is an American progressive news website, with localized and international editions. The site offers news, satire, blogs, and original content, and covers politics, business, entertainment, environment, technology, popular media, lifestyle, culture, comedy, healthy living, women's interests, and local news featuring columnists. It was created to provide a progressive alternative to the conservative news websites such as the Drudge Report. The site offers content posted directly on the site as well as user-generated content via video blogging, audio, and photo. In 2012, the website became the first commercially run United States digital media enterprise to win a Pulitzer Prize. Founded by Andrew Breitbart, Arianna Huffington, Kenneth Lerer, and Jonah Peretti, the site was launched on May 9, 2005 as a counterpart to the Drudge Report. In March 2011, it was acquired by AOL for US$315& ...
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Facilitated Communication
Facilitated communication (FC), or supported typing, is a scientifically discredited technique that attempts to aid communication by people with autism or other communication disabilities who are non-verbal. The facilitator guides the disabled person's arm or hand and attempts to help them type on a keyboard or other device. There is widespread agreement within the scientific community and among disability advocacy organizations that FC is a pseudoscience. Research indicates that the facilitator is the source of the messages obtained through FC, rather than the disabled person. The facilitator may believe they are not the source of the messages due to the ideomotor effect, which is the same effect that guides a Ouija board. Studies have consistently found that FC is unable to provide the correct response to even simple questions when the facilitator does not know the answers to the questions (e.g., showing the patient but not the facilitator an object). In addition, in numerou ...
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Vegetative State
A persistent vegetative state (PVS) or post-coma unresponsiveness (PCU) is a disorder of consciousness in which patients with severe brain damage are in a state of partial arousal rather than true awareness. After four weeks in a vegetative state (VS), the patient is classified as being in a persistent vegetative state. This diagnosis is classified as a permanent vegetative state some months (three in the US and six in the UK) after a non-traumatic brain injury or one year after a traumatic injury. The term unresponsive wakefulness syndrome may be alternatively used, as "vegetative state" has some negative connotations among the public. Definition There are several definitions that vary by technical versus layman's usage. There are different legal implications in different countries. Medical definition Per the British Royal College of Physicians of London, a persistent vegetative state is "a wakeful unconscious state that lasts longer than a few weeks is referred to as a per ...
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Rom Houben
Rom Houben is a comatose Belgian man who was claimed to have the ability to type through facilitated communication, a scientifically discredited technique. Houben was comatose and in a vegetative state for 23 years after a near-fatal automobile accident, but whom according to several of his caregivers, was conscious and paralyzed during the entirety of his hospital stay. In 2010, the claim that Houben was able to communicate was rejected when communication could not be replicated with a different facilitator and by hiding the object to be identified from the view of the facilitator. Background Houben was diagnosed with total locked-in syndrome by Belgian neurologist Steven Laureys in 2006 with the help of modern brain imaging techniques and equipment.Kate Connolly (23 November 2009).Car crash victim trapped in 'coma' for 23 years was conscious. guardian.co.uk. It was claimed that he could communicate by typing into a keyboard with his right hand supported by a communication fac ...
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In Vitro Fertilisation
In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm in vitro ("in glass"). The process involves monitoring and stimulating an individual's ovulatory process, removing an ovum or ova (egg or eggs) from their ovaries and letting sperm fertilise them in a culture medium in a laboratory. After the fertilised egg (zygote) undergoes embryo culture for 2–6 days, it is transferred by catheter into the uterus, with the intention of establishing a successful pregnancy. IVF is a type of assisted reproductive technology used for infertility treatment, gestational surrogacy, and, in combination with pre-implantation genetic testing, avoiding transmission of genetic conditions. A fertilised egg from a donor may implant into a surrogate's uterus, and the resulting child is genetically unrelated to the surrogate. Some countries have banned or otherwise regulate the availability of IVF treatment, giving rise to fertility tourism. Restrictions ...
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