Swainsonine
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Swainsonine
Swainsonine is an indolizidine alkaloid. It is a potent inhibitor of Golgi alpha-mannosidase II, an immunomodulator, and a potential chemotherapy drug. As a toxin in locoweed (likely its primary toxin) it also is a significant cause of economic losses in livestock industries, particularly in North America. It was first isolated from '' Swainsona canescens''. Pharmacology Swainsonine inhibits glycoside hydrolases, specifically N-linked glycosylation. Disruption of Golgi alpha-mannosidase II with swainsonine induces hybrid-type glycans. These glycans have a Man5GlcNAc2 core with processing on the 3-arm that resembles so-called complex-type glycans. The pharmacological properties of this product have not been fully investigated. Sources Some plants do not produce the toxic compound itself; they are host of endophytic fungi which produces swainsonine. Biosynthesis The biosynthesis of swainsonine has been investigated in the fungus ''Rhizoctonia leguminicola'', and it ini ...
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Locoweed
Locoweed (also crazyweed and loco) is a common name in North America for any plant that produces swainsonine, a phytotoxin harmful to livestock. Worldwide, swainsonine is produced by a small number of species, most of them in three genera of the flowering plant family Fabaceae: ''Oxytropis'' and ''Astragalus'' in North America, and ''Swainsona'' in Australia. The term locoweed usually refers only to the North American species of ''Oxytropis'' and ''Astragalus'', but this article includes the other species as well. Some references may list ''Datura stramonium'' as locoweed. Locoweed is relatively palatable to livestock, and some individual animals will seek it out. Livestock poisoned by chronic ingestion of large amounts of swainsonine develop a medical condition known as ''locoism'' (swainsonine disease, swainsonine toxicosis in North America) and ''pea struck'' in Australia. Locoism is reported most often in cattle, sheep, and horses, but has also been reported in elk and deer. I ...
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Ipomoea Carnea
''Ipomoea carnea'', the pink morning glory, is a species of morning glory that grows as a bush. This flowering plant has heart-shaped leaves that are a rich green and long. It can be easily grown from seeds. These seeds are toxic and it can be hazardous to cattle; the toxicity is related to the swainsonine produced by its endophytes, and to bioaccumulation of selenium in the leaves but mostly in the seeds. The stem of ''I. carnea'' can be used for making paper. The plant is also of medicinal value. It contains a component identical to marsilin, a sedative and anticonvulsant. A glycosidic saponin has also been purified from ''I. carnea'' with anticarcinogenic and oxytoxic properties. One selection of ''I. carnea'', 'Inducer', has been used as a rootstock for inducing flowering of sweetpotato cultivars which otherwise prove reticent to produce flowers. Another common name is "bush morning glory", but particularly in temperate North America, that usually refers to '' I. lept ...
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Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids
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Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ...
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Ipomoea Rosea
''Ipomoea'' () is the largest genus in the plant family Convolvulaceae, with over 600 species. It is a large and diverse group, with common names including morning glory, water convolvulus or water spinach, sweet potato, bindweed, moonflower, etc. The genus occurs throughout the tropical and subtropical regions of the world, and comprises annual and perennial herbaceous plants, lianas, shrubs, and small trees; most of the species are twining climbing plants. Their most widespread common name is morning glory, but some species in related genera bear that same common name and some ''Ipomoea'' species are known by different common names. Those formerly separated in ''Calonyction'' (Greek "good" and , , , "night") are called moonflowers. The name ''Ipomoea'' is derived from the Greek , (, ), meaning "woodworm", and (), meaning "resembling". It refers to their twining habit. Uses and ecology Human uses of ''Ipomoea'' include: *Most species have spectacular, colorful fl ...
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Ipomoea Megapotamica
''Ipomoea'' () is the largest genus in the plant family Convolvulaceae, with over 600 species. It is a large and diverse group, with common names including morning glory, water convolvulus or water spinach, sweet potato, bindweed, moonflower, etc. The genus occurs throughout the tropical and subtropical regions of the world, and comprises annual and perennial herbaceous plants, lianas, shrubs, and small trees; most of the species are twining climbing plants. Their most widespread common name is morning glory, but some species in related genera bear that same common name and some ''Ipomoea'' species are known by different common names. Those formerly separated in ''Calonyction'' (Greek "good" and , , , "night") are called moonflowers. The name ''Ipomoea'' is derived from the Greek , (, ), meaning "woodworm", and (), meaning "resembling". It refers to their twining habit. Uses and ecology Human uses of ''Ipomoea'' include: *Most species have spectacular, colorful fl ...
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Ipomoea Subincana
''Ipomoea'' () is the largest genus in the plant family Convolvulaceae, with over 600 species. It is a large and diverse group, with common names including morning glory, water convolvulus or water spinach, sweet potato, bindweed, moonflower, etc. The genus occurs throughout the tropical and subtropical regions of the world, and comprises annual and perennial herbaceous plants, lianas, shrubs, and small trees; most of the species are twining climbing plants. Their most widespread common name is morning glory, but some species in related genera bear that same common name and some ''Ipomoea'' species are known by different common names. Those formerly separated in ''Calonyction'' (Greek "good" and , , , "night") are called moonflowers. The name ''Ipomoea'' is derived from the Greek , (, ), meaning "woodworm", and (), meaning "resembling". It refers to their twining habit. Uses and ecology Human uses of ''Ipomoea'' include: *Most species have spectacular, colorful fl ...
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Ipomoea Verbascoidea
''Ipomoea'' () is the largest genus in the plant family Convolvulaceae, with over 600 species. It is a large and diverse group, with common names including morning glory, water convolvulus or water spinach, sweet potato, bindweed, moonflower, etc. The genus occurs throughout the tropical and subtropical regions of the world, and comprises annual and perennial herbaceous plants, lianas, shrubs, and small trees; most of the species are twining climbing plants. Their most widespread common name is morning glory, but some species in related genera bear that same common name and some ''Ipomoea'' species are known by different common names. Those formerly separated in ''Calonyction'' (Greek "good" and , , , "night") are called moonflowers. The name ''Ipomoea'' is derived from the Greek , (, ), meaning "woodworm", and (), meaning "resembling". It refers to their twining habit. Uses and ecology Human uses of ''Ipomoea'' include: *Most species have spectacular, colorful fl ...
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Jacquemontia Corymbulosa
''Jacquemontia'' is a genus of plants in the morning glory family Convolvulaceae Convolvulaceae (), commonly called the bindweeds or morning glories, is a family of about 60 genera and more than 1,650 species. These species are primarily herbaceous vines, but also include trees, shrubs and herbs. The tubers of several spec .... Species in this genus are commonly known as clustervine. Species Over one hundred species are recognised: * '' Jacquemontia abutiloides'' * '' Jacquemontia acrocephala'' * '' Jacquemontia acuminata'' * '' Jacquemontia aequisepala'' * '' Jacquemontia albida'' * '' Jacquemontia anomala'' * '' Jacquemontia asarifolia'' * '' Jacquemontia bahiensis'' * '' Jacquemontia blanchetii'' * '' Jacquemontia bracteosa'' * '' Jacquemontia browniana'' * '' Jacquemontia capitellata'' * '' Jacquemontia cataractae'' * '' Jacquemontia caudata'' * '' Jacquemontia cayensis'' * '' Jacquemontia cearensis'' * '' Jacquemontia cephalantha'' ...
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Journal Of Agricultural And Food Chemistry
The ''Journal of Agricultural and Food Chemistry'' is a weekly peer-reviewed scientific journal established in 1953 by the American Chemical Society. Since 2015, Thomas Hofmann (Technical University of Munich) has been the editor-in-chief. The journal covers research dealing with the chemistry and biochemistry of agriculture and food including work with chemistry and/or biochemistry as a major component combined with biological/sensory/nutritional/toxicological evaluation related to agriculture and/or food. Abstracting and indexing The journal is abstracted and indexed in Chemical Abstracts Service, Scopus, ProQuest, PubMed, CABI, and the Science Citation Index Expanded. According to the ''Journal Citation Reports'', the ''Journal of Agricultural and Food Chemistry'' has a 2015 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of article ...
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Astragalus Humistratus
''Astragalus'' is a large genus of over 3,000 species of herbs and small shrubs, belonging to the legume family Fabaceae and the subfamily Faboideae. It is the largest genus of plants in terms of described species. The genus is native to temperate regions of the Northern Hemisphere. Common names include milkvetch (most species), locoweed (in North America, some species) and goat's-thorn ( ''A. gummifer'', ''A. tragacantha''). Some pale-flowered vetches (''Vicia'' spp.) are similar in appearance, but they are more vine-like than ''Astragalus''. Description Most species in the genus have pinnately compound leaves. There are annual and perennial species. The flowers are formed in clusters in a raceme, each flower typical of the legume family, with three types of petals: banner, wings, and keel. The calyx is tubular or bell-shaped. Ecology ''Astragalus'' species are used as food plants by the larvae of some Lepidoptera species including many case-bearing moths of the genus ''Col ...
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Astragalus Tephrodes
''Astragalus'' is a large genus of over 3,000 species of herbs and small shrubs, belonging to the legume family Fabaceae and the subfamily Faboideae. It is the largest genus of plants in terms of described species. The genus is native to temperate regions of the Northern Hemisphere. Common names include milkvetch (most species), locoweed (in North America, some species) and goat's-thorn ( ''A. gummifer'', ''A. tragacantha''). Some pale-flowered vetches (''Vicia'' spp.) are similar in appearance, but they are more vine-like than ''Astragalus''. Description Most species in the genus have pinnately compound leaves. There are annual and perennial species. The flowers are formed in clusters in a raceme, each flower typical of the legume family, with three types of petals: banner, wings, and keel. The calyx is tubular or bell-shaped. Ecology ''Astragalus'' species are used as food plants by the larvae of some Lepidoptera species including many case-bearing moths of the genus ''Col ...
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Astragalus Nothoxys
''Astragalus'' is a large genus of over 3,000 species of herbs and small shrubs, belonging to the legume family Fabaceae and the subfamily Faboideae. It is the largest genus of plants in terms of described species. The genus is native to temperate regions of the Northern Hemisphere. Common names include milkvetch (most species), locoweed (in North America, some species) and goat's-thorn ( ''A. gummifer'', ''A. tragacantha''). Some pale-flowered vetches (''Vicia'' spp.) are similar in appearance, but they are more vine-like than ''Astragalus''. Description Most species in the genus have pinnately compound leaves. There are annual and perennial species. The flowers are formed in clusters in a raceme, each flower typical of the legume family, with three types of petals: banner, wings, and keel. The calyx is tubular or bell-shaped. Ecology ''Astragalus'' species are used as food plants by the larvae of some Lepidoptera species including many case-bearing moths of the genus ''Col ...
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