Stromal Cell Protein
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Stromal Cell Protein
Sugar transporter SWEET1, also known as RAG1-activating protein 1 and stromal cell protein (SCP), is a membrane protein that in humans is encoded by the SLC50A1 gene. SWEET1 is the sole transporter from the SLC50 (SWEET) gene family present in the genomes of most animal species, with the exception of the nematode ''Caenorhabditis elegans'', which has seven. SWEET1 is a broadly-expressed glucose transporter. As the SWEET family has been identified relatively recently, the full range of its functions in animals is not yet clear. However, the bovine SLC50A1 homologue is associated with lactose concentration in milk, and the CiRGA homologue in the sea squirt ''Ciona intestinalis'' is essential for tissue differentiation during embryogenesis, especially the development of the notochord. SWEET genes are common in plant genomes, with around twenty paralogues functioning as both sucrose and hexose transporters, and are also associated with pathogen susceptibility. References Furthe ...
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ...
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