Stanley Gartler
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Stanley Gartler
Stanley Michael Gartler (born June 9, 1923) is a cell and molecular biologist and human geneticist. He was the first scientist to offer conclusive evidence for the clonality of human cancers. He showed that HeLa cells had contaminated many cell lines thought to be unique. Stanley Gartler is currently Professor Emeritus of Medicine and Genome Sciences at the University of Washington. Biography Gartler was born in Los Angeles, California in 1923 of Romanian immigrant parents. He attended public school in Los Angeles and completed two years at university (UCLA) before enlisting in the Army Air Force during World War II. He was a radio operator machine gunner and flew combat missions with the 9th Air Force. After the war, on the G.I. Bill, he completed his undergraduate education at UCLA and entered the Ph.D. program in Genetics at UC Berkeley. He originally thought of applying genetics to agricultural work, but near the end of his graduate work he made a career switch and decided to ...
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Los Angeles, California
Los Angeles ( ; es, Los Ángeles, link=no , ), often referred to by its initials L.A., is the largest city in the state of California and the second most populous city in the United States after New York City, as well as one of the world's most populous megacities. Los Angeles is the commercial, financial, and cultural center of Southern California. With a population of roughly 3.9 million residents within the city limits , Los Angeles is known for its Mediterranean climate, ethnic and cultural diversity, being the home of the Hollywood film industry, and its sprawling metropolitan area. The city of Los Angeles lies in a basin in Southern California adjacent to the Pacific Ocean in the west and extending through the Santa Monica Mountains and north into the San Fernando Valley, with the city bordering the San Gabriel Valley to it's east. It covers about , and is the county seat of Los Angeles County, which is the most populous county in the United States with an estim ...
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Sex-linked
Sex linked describes the sex-specific patterns of inheritance and presentation when a gene mutation (allele) is present on a sex chromosome (allosome) rather than a non-sex chromosome ( autosome). In humans, these are termed X-linked recessive, X-linked dominant and Y-linked. The inheritance and presentation of all three differ depending on the sex of both the parent and the child. This makes them characteristically different from autosomal dominance and recessiveness. There are many more X-linked conditions than Y-linked conditions, since humans have several times as many genes on the X chromosome than the Y chromosome. Only females are able to be carriers for X-linked conditions; males will always be affected by any X-linked condition, since they have no second X chromosome with a healthy copy of the gene. As such, X-linked recessive conditions affect males much more commonly than females. In X-linked recessive inheritance, a son born to a carrier mother and an unaffected fat ...
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American College Of Medical Genetics
The American College of Medical Genetics and Genomics (ACMG) is an organization composed of biochemical, clinical, cytogenetic, medical and molecular geneticists, genetic counselors and other health care professionals committed to the practice of medical genetics. History The ACMG, incorporated in 1991, stated mission to give national representation to providers of genetic services and their patients with genetic disorders; to provide education and resources for the medical genetics profession; to improve the health of the public by promoting the development and implementation of methods to diagnose, treat and prevent genetic disease. In 1993, ACMG publishes the first edition of the ''ACMG Standards and Guidelines for Clinical Genetic Laboratories'' and supports the formation of the American Board of Genetic Counseling. The first ''Annual Clinical Genetic Meeting'' is held in 1994. Next year, the College becomes a full member of the Council of Medical Specialty Societies. ACMG ...
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American Society Of Human Genetics
The American Society of Human Genetics (ASHG), founded in 1948, is a professional membership organization for specialists in human genetics. As of 2009, the organization had approximately 8,000 members. The Society's members include researchers, academicians, clinicians, laboratory practice professionals, genetic counselors, nurses, and others who have a special interest in the field of human genetics. As the field of human genetics has expanded, ASHG has founded additional organizations within its membership body, including the following: * National Society of Genetic Counselors, founded in 1979, as an advocacy group for the nascent field of genetic counseling. * American Board of Medical Genetics, founded in 1981, to certify practitioners in human genetics. * American Board of Genetic Counseling, founded in 1991, to certify genetic counselors. * American College of Medical Genetics, founded in 1991, as a specialty board for medical geneticists at the doctoral level. It achieve ...
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American Association For The Advancement Of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the betterment of all humanity. It is the world's largest general scientific society, with over 120,000 members, and is the publisher of the well-known scientific journal ''Science''. History Creation The American Association for the Advancement of Science was created on September 20, 1848, at the Academy of Natural Sciences in Philadelphia, Pennsylvania. It was a reformation of the Association of American Geologists and Naturalists. The society chose William Charles Redfield as their first president because he had proposed the most comprehensive plans for the organization. According to the first constitution which was agreed to at the September 20 meeting, the goal of ...
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Public Health Service
In public relations and communication science, publics are groups of individual people, and the public (a.k.a. the general public) is the totality of such groupings. This is a different concept to the sociological concept of the ''Öffentlichkeit'' or public sphere. The concept of a public has also been defined in political science, psychology, marketing, and advertising. In public relations and communication science, it is one of the more ambiguous concepts in the field. Although it has definitions in the theory of the field that have been formulated from the early 20th century onwards, and suffered more recent years from being blurred, as a result of conflation of the idea of a public with the notions of audience, market segment, community, constituency, and stakeholder. Etymology and definitions The name "public" originates with the Latin '' publicus'' (also '' poplicus''), from ''populus'', to the English word 'populace', and in general denotes some mass population ("the p ...
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Walter Nelson-Rees
Walter Nelson-Rees (11 January 1929 – 23 January 2009) was a cell culture worker and cytogeneticist who helped expose the problem of cross-contamination of cell lines. He used chromosome banding to show that many immortal cell lines, previously thought to be unique, were actually HeLa cell lines. The HeLa cells had contaminated and overgrown the other cell lines. Biography He was born on January 11, 1929. Nelson-Rees retired in 1980. In 2005 he received the Lifetime Achievement Award, from thSociety for In Vitro Biology (SIVB) He died on January 23, 2009, in San Francisco, California San Francisco (; Spanish for " Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the fourth most populous in California and 17th ..., from complications from a broken hip. References {{DEFAULTSORT:Nelson-Rees Cell biology 1929 births 2009 deaths Cell biologists ...
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Nellie Auesperg
Nelly (born 1974) is an American rapper, singer, actor and entrepreneur. Nelly or Nellie may also refer to: Places * Nellie, Ohio, an American village * Nellie, Assam, a town in Nagaon district * Nelly Island, Antarctica * Nelly Island, Bermuda * Mount Nelly, Bolivia, a stratovolcano in the Andes People * Nelly (given name), a list of people with the given name or nickname Nelly or Nellie * Nelly (Egyptian entertainer), Egyptian singer, actor, and radio and television personality and presenter * Nelly Furtado, a Canadian singer, songwriter and record producer * Nelly's (1899–1998), Greek photographer (real name Elli Souyioultzoglou-Seraïdari) * Harry Nelly, head coach of the Army college football program from 1908 to 1910 Arts and entertainment * Nelly (2004 film), a French film * Nelly (2016 film), a Canadian film * ''Nellie'', a boat in Joseph Conrad's novella ''Heart of Darkness'' Other uses * , a Danish steamship in service between 1928 and 1936 * "Nellie", a proto ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ...
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George Gey
George Otto Gey ( ; July 6, 1899 – November 8, 1970) was the cell biologist at Johns Hopkins Hospital who is credited with propagating the HeLa cell line from Henrietta Lacks' cervical tumor. He spent over 35 years developing numerous scientific breakthroughs under the Johns Hopkins Medical School and Hospital. Early life and education Gey was born in Pittsburgh, Pennsylvania on July 6, 1899, the son of German immigrants Frank and Emma Gey. He had an older brother and younger sister. Gey's parents immigrated from Germany, and according to the 1910 United States Census, they lived in suburban Pittsburgh. Gey graduated Peabody High School, and received undergraduate degree in biology from the University of Pittsburgh in 1920. He worked as a carpenter and a mason to help pay his way through college. Around 1926, he married Margaret K. (1900–1989), and they later moved to Baltimore where he would earn his medical degree from Johns Hopkins University. Gey was in medical school ...
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Henrietta Lacks
Henrietta Lacks (born Loretta Pleasant; August 1, 1920 – October 4, 1951) Note: Some sources report her birthday as August 2, 1920, vs. August 1, 1920. was an African-American woman whose cancer cells are the source of the HeLa cell line, the first immortalized human cell line and one of the most important cell lines in medical research. An immortalized cell line reproduces indefinitely under specific conditions, and the HeLa cell line continues to be a source of invaluable medical data to the present day. Lacks was the unwitting source of these cells from a tumor biopsied during treatment for cervical cancer at Johns Hopkins Hospital in Baltimore, Maryland, U.S., in 1951. These cells were then cultured by George Otto Gey, who created the cell line known as HeLa, which is still used for medical research. As was then the practice, no consent was required to culture the cells obtained from Lacks's treatment. Neither she nor her family were compensated for their extracti ...
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Cell Culture
Cell culture or tissue culture is the process by which cells are grown under controlled conditions, generally outside of their natural environment. The term "tissue culture" was coined by American pathologist Montrose Thomas Burrows. This technique is also called micropropagation. After the cells of interest have been isolated from living tissue, they can subsequently be maintained under carefully controlled conditions the need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases ( CO2, O2), and regulates the physio-chemical environment (pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown ...
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