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Stanley Center For Psychiatric Research
The Stanley Center for Psychiatric Research at Broad Institute of MIT and Harvard is a multi-disciplinary biomedical research program located in Cambridge, Massachusetts that studies the biological basis of psychiatric disease. The center was founded in 2007 with funding from philanthropists Ted and Vada Stanley. History The Stanley Center for Psychiatric Research at Broad Institute was launched in 2007 with Edward Scolnick, M.D., former head of research and development at Merck Research Laboratories, as its founding director. Within a year of its inception, researchers at the center and their international collaborators published a paper on their analysis of a collection of more than 7,000 genetic samples for schizophrenia. The center later launched efforts to collect and sequence genetic samples for such conditions as bipolar disorder, autism spectrum disorders (ASDs) and attention deficit hyperactivity disorder (ADHD), in addition to schizophrenia. In early 2012, Scolnick ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Basic Research
Basic research, also called pure research or fundamental research, is a type of scientific research with the aim of improving scientific theories for better understanding and prediction of natural or other phenomena. In contrast, applied research uses scientific theories to develop technology or techniques which can be used to intervene and ''alter'' natural or other phenomena. Though often driven simply by curiosity,"Curiosity creates cures: The value and impact of basic research , , |
Bipolar Disorder
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that last from days to weeks each. If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy or irritable, and they often make impulsive decisions with little regard for the consequences. There is usually also a reduced need for sleep during manic phases. During periods of depression, the individual may experience crying and have a negative outlook on life and poor eye contact with others. The risk of suicide is high; over a period of 20 years, 6% of those with bipolar disorder died by suicide, while 30–40% engaged in self-harm. Other mental health issues, such as anxiety disorders and substance use disorders, are commonly associated with bipolar disorder. While the causes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karolinska Institute
The Karolinska Institute (KI; sv, Karolinska Institutet; sometimes known as the (Royal) Caroline Institute in English) is a research-led medical university in Solna within the Stockholm urban area of Sweden. The Karolinska Institute is consistently ranked amongst the world's best medical schools, ranking 6th worldwide for medicine in 2021. The Nobel Assembly at the Karolinska Institute awards the Nobel Prize in Physiology or Medicine. The assembly consists of fifty professors from various medical disciplines at the university. The current rector of Karolinska Institute is Ole Petter Ottersen, who took office in August 2017. The Karolinska Institute was founded in 1810 on the island of Kungsholmen on the west side of Stockholm; the main campus was relocated decades later to Solna, just outside Stockholm. A second campus was established more recently in Flemingsberg, Huddinge, south of Stockholm. The Karolinska Institute is Sweden's third oldest medical school, after Uppsala ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Icahn School Of Medicine At Mount Sinai
The Icahn School of Medicine at Mount Sinai (ISMMS or Mount Sinai), formerly the Mount Sinai School of Medicine, is a private medical school in New York City. It is the academic teaching arm of the Mount Sinai Health System, which manages eight hospital campuses in the New York metropolitan area, including Mount Sinai Hospital and the New York Eye and Ear Infirmary. Mount Sinai is ranked #11 among American medical schools by the 2023 '' U.S. News & World Report''.https://www.usnews.com/best-graduate-schools/top-medical-schools/icahn-school-of-medicine-at-mount-sinai-04072 In 2021, it was ranked 15th in the country for biomedical research and leads the country in research funding from the National Institutes of Health for neuroscience (#2) and genetics (#2). It attracted over $400 million in total NIH funding in 2021. Mount Sinai's faculty includes 23 elected members of the National Academies of Sciences, Engineering, and Medicine and 40 members of the American Society for Cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiff University School Of Medicine
The Cardiff University School of Medicine ( cy, Ysgol Feddygaeth Prifysgol Caerdydd) is the medical school of Cardiff University and is located in Cardiff, Wales, UK. Founded in 1893 as part of the University College of South Wales and Monmouthshire, it is the older of the two medical schools in Wales. It is one of the largest medical schools in the United Kingdom, employing nearly 500 academic and 300 support staff; and with over 1000 undergraduate and 1100 postgraduate students enrolled on medical and scientific courses. The school has an annual financial turnover of over £50 million, of which nearly half comes from competitive external research funding. The school is based at the University Hospital of Wales in Cardiff. History Origins The medical school was founded as ''Cardiff Medical School'' in 1893 when the Departments of Anatomy, Physiology and Pharmacology were established at University College of South Wales and Monmouthshire (now Cardiff University). Much of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has foundations in applied mathematics, chemistry, and genetics. It differs from biological computing, a subfield of computer engineering which uses bioengineering to build computers. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational methods for quickly interpreting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
McLean Hospital
McLean Hospital () (formerly known as Somerville Asylum and Charlestown Asylum) is a psychiatric hospital in Belmont, Massachusetts. It is noted for its clinical staff expertise and neuroscience research and is also known for the large number of famous people who have been treated there. McLean maintains the world's largest neuroscientific and psychiatric research program in a private hospital. It is the largest psychiatric facility of Harvard Medical School, an affiliate of Massachusetts General Hospital, and part of Mass General Brigham, which also includes Brigham and Women's Hospital. History Map of the McLean Insane Asylum from an 1884 atlas of Somerville, Massachusetts McLean was founded in 1811 in a section of Charlestown, Massachusetts that is now a part of Somerville, Massachusetts. Originally named Asylum for the Insane, it was the first institution organized by a group of prominent Bostonians who were concerned about homeless mentally ill persons "abounding on the st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard T
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard Faculty Of Arts And Sciences
The Harvard Faculty of Arts and Sciences (FAS) is the largest of the ten faculties that constitute Harvard University. Headquartered principally in Cambridge, Massachusetts, and centered in the historic Harvard Yard, FAS is the only faculty responsible for both undergraduate and graduate education. FAS administers the courses offered at Harvard College, the Harvard Graduate School of Arts and Sciences, The John A. Paulson School of Engineering and Applied Sciences (SEAS), and the Harvard Division of Continuing Education. It is headed by Dean Claudine Gay. As of Fall 2019, FAS comprised 1221 total faculty, including 719 tenured and tenure-track professors as well as 502 other professors, lecturers, preceptors, and visiting faculty in some 30 academic departments in the arts and humanities, the social sciences, the natural sciences, and the engineering and applied sciences. There are approximately 6,800 undergraduates (Harvard College) and 4,500 graduate students ( Harvard Graduat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Genome
The human genome is a complete set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome pairs in cell nuclei and in a small DNA molecule found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. Human genomes include both protein-coding DNA sequences and various types of DNA that does not encode proteins. The latter is a diverse category that includes DNA coding for non-translated RNA, such as that for ribosomal RNA, transfer RNA, ribozymes, small nuclear RNAs, and several types of regulatory RNAs. It also includes promoters and their associated gene-regulatory elements, DNA playing structural and replicatory roles, such as scaffolding regions, telomeres, centromeres, and origins of replication, plus large numbers of transposable elements, inserted viral DNA, non-functional pseudogenes and simple, highly-repetitive sequences. Introns make up a large percentage of non-coding DNA. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychiatric Genomics Consortium
The Psychiatric Genomics Consortium (PGC) is an international consortium of scientists dedicated to conducting meta- and mega-analyses of genomic-wide genetic data, with a focus on psychiatric disorders. It is the largest psychiatric consortium ever created, including over 800 researchers from 38 countries as of 2019. Its goal is to generate information about the genetics of psychiatric conditions that will be "actionable", that is, "genetic findings whose biological implications can be used to improve diagnosis, develop rational therapeutics, and craft mechanistic approaches to primary prevention". The consortium makes the main findings from its research freely available for use by other researchers. History The PGC was founded in early 2007, originally as the Psychiatric Genome Wide Association Consortium. One of its founders was Patrick F. Sullivan (UNC School of Medicine), who now serves as its lead principal investigator. It was initially a branch of the Genetic Association I ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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