Spirillum Minus
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Spirillum Minus
''Spirillum minus'' is an organism associated with rat-bite fever (specifically sodoku) that has never been fully identified and was assigned to the genus ''Spirillum'' in 1887 based on morphology, although it is not a validly published name. As ''Spirillum'' species generally obligately microaerophiles and are not found in mammals, this organism may be misclassified. Sequencing data should help to resolve this question. This organism is presumed to be a bacterium. It stains gram-negative Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall ... and has a coiled rod shape. It does not grow ''in vitro'', and requires inoculation in animals for growth. No attempts to sequence the organism are known as of 2015. References {{Taxonbar, from=Q7577829 Nitrosomonadales ...
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Rat-bite Fever
Rat-bite fever (RBF) is an acute, febrile human illness caused by bacteria transmitted by rodents, in most cases, which is passed from rodent to human by the rodent's urine or mucous secretions. Alternative names for rat-bite fever include streptobacillary fever, streptobacillosis, spirillary fever, bogger, and epidemic arthritic erythema. It is a rare disease spread by infected rodents and caused by two specific types of bacteria: # ''Streptobacillus moniliformis'', the only reported bacteria that causes RBF in North America (streptobacillary RBF) # ''Spirillum minus'', common in Asia (spirillary RBF, also known as sodoku). Most cases occur in Japan, but specific strains of the disease are present in the United States, Europe, Australia, and Africa. Some cases are diagnosed after patients were exposed to the urine or bodily secretions of an infected animal. These secretions can come from the mouth, nose, or eyes of the rodent. The majority of cases are due to the animal's bite. ...
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Sodoku
Sodoku (鼠毒) is a bacterial zoonotic disease. It is caused by the Gram-negative rod ''Spirillum minus'' (also known as ''Spirillum minor''). It is a form of rat-bite fever (RBF). Signs and symptoms The initial scratch or wound caused by a bite from a carrier rodent results in mild inflammatory reactions and ulcerations. The wounds may heal initially, but reappear with the onset of symptoms. The symptoms include recurring fever, with body temperature 101–104°F (38–40°C). The fever lasts for 2–4 days, but recurs generally at 4–8 weeks. This cycle may continue for months or years. The other symptoms include regional lymphadenitis, malaise, and headache. The complications include myocarditis, endocarditis, hepatitis, splenomegaly, and meningitis. Causes The infections are acquired through rat bites or scratches. It can occur as nosocomial infections (i.e., acquired from hospitals), or due to exposure or close associations with animals preying on rats, mice, squirrels, e ...
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Spirillum
''Spirillum'' is a genus of Gram-negative bacteria in the family ''Spirillaceae'' of the ''Nitrosomonadales'' of the ''Betaproteobacteria''.Garrity, George M.; Brenner, Don J.; Krieg, Noel R.; Staley, James T. (eds.) (2005). Bergey's Manual of Systematic Bacteriology, Volume Two: The Proteobacteria, Part C: The Alpha-, Beta-, Delta-, and Epsilonproteobacteria. New York, New York: Springer. pp. 354–361. .Podkopaeva (D.), Grabovich (M.), Kuever (J.), Lysenko (A.M.), Tourova (T.P.), Kolganova (T.V.) and Dubinia (G.): Proposal of Spirillum winogradskyi sp. nov., a novel microaerophilic species, an amended description of the genus Spirillum and Request for an Opinion regarding the status of the species Spirillum volutans Ehrenberg 1832. Int. J. Syst. Evol. Microbiol., 2009, 59, 2916-2920. There are two species of ''Spirillum'' with validly or effectively published names - ''Spirillum winogradskyi'' and ''Spirillum volutans''. Other "species" classified as ''Spirillum'' such as "' ...
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Microaerophilic
A microaerophile is a microorganism that requires environments containing lower levels of dioxygen than that are present in the atmosphere (i.e. < 21% O2; typically 2–10% O2) for optimal growth. A more restrictive interpretation requires the microorganism to be obligate in this requirement. Many microaerophiles are also capnophiles, requiring an elevated concentration of (e.g. 10% CO2 in the case of '' Campylobacter'' ). The original definitio ...
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Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', ''Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipo ...
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