Solid Cell Nests
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Solid Cell Nests
Solid cell nests, often abbreviated as SCN, also known as solid cell rests, are specific groups of cells found in the thyroid gland of babies. Typically they are a fraction of a millimeter in size but can rarely become larger. They are considered to be the remains of the ultimobranchial body that exists in early development.{{cite book , last1=Rosai , first1=Juan , title=Rosai and Ackerman's Surgical Pathology E-Book , date=2011 , publisher=Elsevier Health Sciences , isbn=978-0323088046 , page=489 , url=https://books.google.com/books?id=1CKX7aGBbUsC&pg=PA489 , language=en References Pathology ...
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Thyroid Gland
The thyroid, or thyroid gland, is an endocrine gland in vertebrates. In humans it is in the neck and consists of two connected lobe (anatomy), lobes. The lower two thirds of the lobes are connected by a thin band of Connective tissue, tissue called the thyroid isthmus. The thyroid is located at the front of the neck, below the Adam's apple. Microscopically, the functional unit of the thyroid gland is the spherical Thyroid follicular cell#Location, thyroid follicle, lined with thyroid follicular cell, follicular cells (thyrocytes), and occasional parafollicular cells that surround a follicular lumen, lumen containing colloid. The thyroid gland secretes three hormones: the two thyroid hormonestriiodothyronine, triiodothyronine (T3) and thyroid hormone, thyroxine (T4)and a peptide hormone, calcitonin. The thyroid hormones influence the basal metabolic rate, metabolic rate and protein biosynthesis, protein synthesis, and in children, growth and development. Calcitonin plays a role in ...
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Ultimobranchial Body
The ultimopharyngeal body, or ultimobranchial body or ultimobranchial gland is a small organ found in the neck region of many animals. In humans, it develops from the fourth pharyngeal pouch into the parafollicular cells of the thyroid to produce calcitonin. It may not develop in DiGeorge syndrome. Structure The ultimopharyngeal body is a small organ of the neck. It is found in many animals. In humans, it develops into other tissues. Development In humans, the ultimopharyngeal body is an embryological structure, and is a derivative of the ventral recess of the fourth pharyngeal pouch. It is technically from the fifth pharyngeal pouch, but this is rudimentary and merges with the fourth. It develops into the parafollicular cells of the thyroid. The cells that give rise to the parafollicular cells are derivatives of endoderm. Endoderm cells migrate and associate with the ultimopharyngeal body during development. Function In humans, the ultimopharyngeal body develops into the ...
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