Sirius Red
Sirius Red F 3B (Direct Red 80) is an azo dye primarily used in staining methods for collagen Collagen () is the main structural protein in the extracellular matrix found in the body's various connective tissues. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole ... and amyloid. It has the molecular formula C45H26N10Na6O21S6. In histology, sirius red staining is used in various domains of diagnostic to observe fibrosis levels in a lot of cases of inflammation induced by cancer, vascular or metabolic pathologies. In bright field microscopy the following can be observed: * The nuclei in yellow * The cytoplasm in yellow * Collagen fibers in red * Muscular fibers in yellow * Red blood cells in yellow See also * Collagen Hybridizing Peptide, a peptide that stains denatured collagen in tissues References Staining dyes Azo dyes {{Stains ...
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