Simplexvirus
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Simplexvirus
''Simplexvirus'' is a genus of viruses in the order ''Herpesvirales'', in the family ''Herpesviridae'', in the subfamily ''Alphaherpesvirinae''. Humans and mammals serve as natural hosts. Diseases associated with this genus include skin vesicles or mucosal ulcers, rarely encephalitis, and meningitis. Species The following 15 species are assigned to the genus: * '' Ateline alphaherpesvirus 1'' * '' Bovine alphaherpesvirus 2'' * '' Cercopithecine alphaherpesvirus 2'' * ''Human alphaherpesvirus 1'' * '' Human alphaherpesvirus 2'' * '' Leporid alphaherpesvirus 4'' * ''Macacine alphaherpesvirus 1'' * '' Macacine alphaherpesvirus 2'' * '' Macacine alphaherpesvirus 3'' * ''Macropodid alphaherpesvirus 1'' * ''Macropodid alphaherpesvirus 2 ''Macropodid alphaherpesvirus 2'' (MaHV-2) is a species of herpesvirus in the genus ''Simplexvirus''. It was officially accepted as a valid species by the International Committee on Taxonomy of Viruses in 2004. Hosts ''Macropodid alphaherpe ... ...
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Macacine Alphaherpesvirus 1
B-virus (''Macacine alphaherpesvirus 1''; McHV-1; formerly ''Macacine herpesvirus 1'', ''Cercopithecine herpesvirus 1'', CHV-1), ''Herpesvirus simiae'', or ''Herpes virus B'' is the ''Simplexvirus'' infecting macaque monkeys. B virus is very similar to HSV-1, and as such, this neurotropic virus is not found in the blood. In the natural host, the virus exhibits pathogenesis similar to that of cold sores in humans. Conversely, when humans are zoonotically infected with B virus, patients can present with a severe encephalitis, resulting in permanent neurological dysfunction or death. Severity of the disease increases for untreated patients, with a case fatality rate of approximately 80%. Early diagnosis and subsequent treatment are crucial to human survival of the infection. B virus is the only identified old-world-monkey herpesvirus that displays severe pathogenicity in humans. There have been a number of accidental infections and fatalities of researchers working with rhesus monk ...
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Alphaherpesvirinae
''Alphaherpesvirinae'' is a subfamily of viruses in the family ''Herpesviridae'', primarily distinguished by reproducing more quickly than other subfamilies in the ''Herpesviridae''. In animal virology the most important herpesviruses belong to the Alphaherpesvirinae. Pseudorabies virus is the causative agent of Aujeszky's disease in pigs and ''Bovine herpesvirus 1'' is the causative agent of bovine infectious rhinotracheitis and pustular vulvovaginitis. Mammals serve as natural hosts. There are currently 45 species in this subfamily, divided among 5 genera with one species unassigned to a genus. Diseases associated with this subfamily include: HHV-1 and HHV-2: skin vesicles or mucosal ulcers, rarely encephalitis and meningitis, HHV-3: chickenpox (varicella) and shingles, GaHV-2: Marek's disease. Genera ''Alphaherpesvirinae'' consists of the following five genera: * ''Iltovirus'' * ''Mardivirus'' * ''Scutavirus'' * ''Simplexvirus'' * ''Varicellovirus'' The species ''Chelo ...
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Macropodid Alphaherpesvirus 1
''Macropodid alphaherpesvirus 1'' (MaHV-1) is a species of herpesvirus in the genus ''Simplexvirus''. It was officially accepted as a valid species by the International Committee on Taxonomy of Viruses in 2004. Hosts It has been detected in captive parma wallabies ('' Macropus parma'') while some other marsupial species have been found to be susceptible to infection when experimentally inoculated. File:Parma Wallaby.jpg, Illustration of healthy ''Macropus parma'' See also * ''Macropodid alphaherpesvirus 2 ''Macropodid alphaherpesvirus 2'' (MaHV-2) is a species of herpesvirus in the genus ''Simplexvirus''. It was officially accepted as a valid species by the International Committee on Taxonomy of Viruses in 2004. Hosts ''Macropodid alphaherpe ...'' References Further reading * * * * Alphaherpesvirinae {{Virus-stub ...
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Macacine Alphaherpesvirus 2
''Macacine alphaherpesvirus 2'' (McHV-2) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Alphaherpesvirinae {{Virus-stub ...
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Saimiriine Alphaherpesvirus 1
''Saimiriine alphaherpesvirus 1'' (SaHV-1) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Alphaherpesvirinae {{Virus-stub ...
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Pteropodid Alphaherpesvirus 1
''Pteropodid alphaherpesvirus 1'' (PtHV-1) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Alphaherpesvirinae {{Virus-stub ...
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Papiine Alphaherpesvirus 2
''Papiine alphaherpesvirus 2'' (PaHV-2) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Alphaherpesvirinae {{Virus-stub ...
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Panine Alphaherpesvirus 3
''Panine alphaherpesvirus 3'' (PnHV-3) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References External links * Alphaherpesvirinae {{Virus-stub ...
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Macropodid Alphaherpesvirus 2
''Macropodid alphaherpesvirus 2'' (MaHV-2) is a species of herpesvirus in the genus ''Simplexvirus''. It was officially accepted as a valid species by the International Committee on Taxonomy of Viruses in 2004. Hosts ''Macropodid alphaherpesvirus 2'' has been detected in two species of captive macropods: grey dorcopsis (''Dorcopsis luctuosa'') and quokkas (''Setonix brachyurus''). File:HalmaturusLuctuosusKeulemans.jpg, Illustration of healthy ''Dorcopsis luctuosa'' File:Setonix brachyurus 2 Gould.jpg, Illustration of healthy ''Setonix brachyurus'' See also * ''Macropodid alphaherpesvirus 1 ''Macropodid alphaherpesvirus 1'' (MaHV-1) is a species of herpesvirus in the genus ''Simplexvirus''. It was officially accepted as a valid species by the International Committee on Taxonomy of Viruses in 2004. Hosts It has been detected in c ...'' References Further reading * * Alphaherpesvirinae {{Virus-stub ...
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Macacine Alphaherpesvirus 3
''Macacine alphaherpesvirus 3'' (McHV-3) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References Alphaherpesvirinae {{Virus-stub ...
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Human Alphaherpesvirus 1
''Human alphaherpesvirus 1'' (HHV-1) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales''. Evolution The ''Human alphaherpesvirus 1'' virus can be classified into six clades. Four of these occur in East Africa, one in East Asia and one in Europe and North America. This suggests that the virus may have originated in East Africa. The most recent common ancestor of the Eurasian strains appears to have evolved ~60,000 years ago. Pathology ''Human alphaherpesvirus 1'' infects humans, most often as cold sores. It is very common and contagious; about 67% of the world population under the age of 50 has ''Human alphaherpesvirus 1''. It is often acquired orally during childhood. It may also be sexually transmitted, including contact with saliva, such as kissing and mouth-to-genital contact (oral sex). The virus tends to reside in the trigeminal ganglia. This species appears to be particularly dama ...
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Leporid Alphaherpesvirus 4
''Leporid alphaherpesvirus 4'' (LeHV-4) is a species of virus in the genus ''Simplexvirus'', subfamily ''Alphaherpesvirinae'', family ''Herpesviridae'', and order ''Herpesvirales The ''Herpesvirales'' is an order of dsDNA viruses (Baltimore group I) with animal hosts, characterised by a common morphology consisting of an icosahedral capsid enclosed in a glycoprotein-containing lipid envelope. Common infections in humans c ...''. References External links * Alphaherpesvirinae {{Virus-stub ...
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