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Simple Explanation
"Simple Explanation" is the 20th episode of the fifth season of ''House''. It first aired on April 6, 2009. Plot As Eddie Novack (Meat Loaf) lies on his deathbed, his wife Charlotte is stricken with respiratory failure. The team takes Charlotte's case and wheels Eddie into her room, as he seems to gain strength when he sees her suffering. Taub suggests she could have picked up something in Hawaii when she went there, and Foreman suggests melioidosis. They start her on an IV drip and aciclovir, which works, until she starts gasping. Thirteen suggests polyserositis, so the team starts Charlotte on indomethacin. In the meantime, Taub does a hormone panel on Eddie which turns out normal, so he does an echo-cardiogram on him as well to see if his heart's improving, but it isn't. Unusually, Kutner does not show up for work, and House dispatches Thirteen and Foreman to check his apartment. Thirteen finds Kutner's body; he has died by suicide. The team must then try to save Charlotte w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
House (TV Series)
''House'' (also called ''House, M.D.'') is an American medical drama television series that originally ran on the Fox network for eight seasons, from November 16, 2004, to May 21, 2012. The series' main character is Dr. Gregory House (Hugh Laurie), an unconventional, misanthropic medical genius who, despite his dependence on pain medication, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. The series' premise originated with Paul Attanasio, while David Shore, who is credited as creator, was primarily responsible for the conception of the title character. The series' executive producers included Shore, Attanasio, Attanasio's business partner Katie Jacobs, and film director Bryan Singer. It was filmed largely in a neighborhood and business district in Los Angeles County's Westside called Century City. The show received high critical acclaim, and was consistently one of the highest rated series in the United States. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Echocardiography
An echocardiography, echocardiogram, cardiac echo or simply an echo, is an ultrasound of the heart. It is a type of medical imaging of the heart, using standard ultrasound or Doppler ultrasound. Echocardiography has become routinely used in the diagnosis, management, and follow-up of patients with any suspected or known heart diseases. It is one of the most widely used diagnostic imaging modalities in cardiology. It can provide a wealth of helpful information, including the size and shape of the heart (internal chamber size quantification), pumping capacity, location and extent of any tissue damage, and assessment of valves. An echocardiogram can also give physicians other estimates of heart function, such as a calculation of the cardiac output, ejection fraction, and diastolic function (how well the heart relaxes). Echocardiography is an important tool in assessing wall motion abnormality in patients with suspected cardiac disease. It is a tool which helps in reaching an ear ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Major Depressive Disorder
Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, the term was adopted by the American Psychiatric Association for this symptom cluster under mood disorders in the 1980 version of the ''Diagnostic and Statistical Manual of Mental Disorders'' (DSM-III), and has become widely used since. The diagnosis of major depressive disorder is based on the person's reported experiences, behavior reported by relatives or friends, and a mental status examination. There is no laboratory test for the disorder, but testing may be done to rule out physical conditions that can cause similar symptoms. The most common time of onset is in a person's 20s, with females affected about twice as often as males. The course of the disorder varies widely, from one epis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Chase
Robert Chase, M.D. is a fictional character on the Fox medical drama ''House''. He is portrayed by Jesse Spencer. His character was a part of the team of diagnosticians who worked under Gregory House until the end of the third season when House fires him. However, he resumed work at the hospital as a surgeon, and was re-hired by House in season 6. Robert Chase is the longest-serving member of House's staff. Chase has been attracted to Allison Cameron since season 3 of the show and embarks on a romantic relationship with her in "Human Error." In "Post Mortem," he left the Diagnostic Team after realizing he was in the same position as he was 10 years earlier, unlike all of the other former members of the team. However, in the series finale, he rejoins the hospital as the new Head of Diagnostic Medicine, replacing the (supposedly) dead House. Characterization Chase is Australian and was born around the year 1979. His Czech father, Rowan Chase, was a wealthy and world-renowned rheu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimony
Antimony is a chemical element with the symbol Sb (from la, stibium) and atomic number 51. A lustrous gray metalloid, it is found in nature mainly as the sulfide mineral stibnite (Sb2S3). Antimony compounds have been known since ancient times and were powdered for use as medicine and cosmetics, often known by the Arabic name kohl. The earliest known description of the metal in the West was written in 1540 by Vannoccio Biringuccio. China is the largest producer of antimony and its compounds, with most production coming from the Xikuangshan Mine in Hunan. The industrial methods for refining antimony from stibnite are roasting followed by reduction with carbon, or direct reduction of stibnite with iron. The largest applications for metallic antimony are in alloys with lead and tin, which have improved properties for solders, bullets, and plain bearings. It improves the rigidity of lead-alloy plates in lead–acid batteries. Antimony trioxide is a prominent additive for halo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visceral Leishmaniasis
Visceral leishmaniasis (VL), also known as kala-azar (Hindi: kālā āzār, "black sickness") or "black fever", is the most severe form of leishmaniasis and, without proper diagnosis and treatment, is associated with high fatality. Leishmaniasis is a disease caused by protozoan parasites of the genus ''Leishmania''. The parasite migrates to the internal organs such as the liver, spleen (hence "visceral"), and bone marrow, and, if left untreated, will almost always result in the death of the host. Signs and symptoms include fever, weight loss, fatigue, anemia, and substantial swelling of the liver and spleen. Of particular concern, according to the World Health Organization (WHO), is the emerging problem of HIV/VL co-infection. VL is the second-largest parasitic killer in the world (after malaria), responsible for an estimated 20,000 to 30,000 deaths each year worldwide. Upendranath Brahmachari synthesised urea stibamine (carbostibamide) in 1922 and determined that it was an ef ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rio De Janeiro
Rio de Janeiro ( , , ; literally 'River of January'), or simply Rio, is the capital of the state of the same name, Brazil's third-most populous state, and the second-most populous city in Brazil, after São Paulo. Listed by the GaWC as a beta global city, Rio de Janeiro is the sixth-most populous city in the Americas. Part of the city has been designated as a World Heritage Site, named "Rio de Janeiro: Carioca Landscapes between the Mountain and the Sea", on 1 July 2012 as a Cultural Landscape. Founded in 1565 by the Portuguese, the city was initially the seat of the Captaincy of Rio de Janeiro, a domain of the Portuguese Empire. In 1763, it became the capital of the State of Brazil, a state of the Portuguese Empire. In 1808, when the Portuguese Royal Court moved to Brazil, Rio de Janeiro became the seat of the court of Queen Maria I of Portugal. She subsequently, under the leadership of her son the prince regent João VI of Portugal, raised Brazil to the dignity of a k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aneurysm
An aneurysm is an outward bulging, likened to a bubble or balloon, caused by a localized, abnormal, weak spot on a blood vessel wall. Aneurysms may be a result of a hereditary condition or an acquired disease. Aneurysms can also be a nidus (starting point) for clot formation (thrombosis) and embolization. As an aneurysm increases in size, the risk of rupture, which leads to uncontrolled bleeding, increases. Although they may occur in any blood vessel, particularly lethal examples include aneurysms of the Circle of Willis in the brain, aortic aneurysms affecting the thoracic aorta, and abdominal aortic aneurysms. Aneurysms can arise in the heart itself following a heart attack, including both ventricular and atrial septal aneurysms. There are congenital atrial septal aneurysms, a rare heart defect. Etymology The word is from Greek: ἀνεύρυσμα, aneurysma, "dilation", from ἀνευρύνειν, aneurynein, "to dilate". Classification Aneurysms are classified by type, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allison Cameron
Allison Cameron, M.D., is a fictional character on the Fox medical drama ''House'', portrayed by American actress Jennifer Morrison. An immunologist, Cameron was a member of Dr. Gregory House's team of handpicked specialists at Princeton-Plainsboro Teaching Hospital's Department of Diagnostic Medicine. She returned for the final episode of the series, " Everybody Dies". Personality At the start of the show, Cameron was the only woman on House's initial diagnostic team. She is known for her honesty, sincerity, idealism and strong ethical center. Even so, she is not out of her depth teasing others, as she does when alone with Chase, telling him that women can have hour-long orgasms (in response to Foreman telling her Chase is interested but shy); but, when Foreman enters, she acts completely deadpan. She is a deist, claiming "I believe in a higher order that's in control of what happens, but not in one anthropomorphic entity called 'God' that's concerned with the everyday work ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alpha 1-antitrypsin Deficiency
Alpha-1 antitrypsin deficiency (A1AD or AATD) is a genetic disorder that may result in lung disease or liver disease. Onset of lung problems is typically between 20 and 50 years of age. This may result in shortness of breath, wheezing, or an increased risk of lung infections. Complications may include chronic obstructive pulmonary disease (COPD), cirrhosis, neonatal jaundice, or panniculitis. A1AD is due to a mutation in the SERPINA1 gene that results in not enough alpha-1 antitrypsin (A1AT). Risk factors for lung disease include tobacco smoking and environmental dust. The underlying mechanism involves unblocked neutrophil elastase and buildup of abnormal A1AT in the liver. It is autosomal co-dominant, meaning that one defective allele tends to result in milder disease than two defective alleles. The diagnosis is suspected based on symptoms and confirmed by blood tests or genetic tests. Treatment of lung disease may include bronchodilators, inhaled steroids, and, when infect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
James Wilson (House)
James Evan Wilson, M.D., is a fictional character on the Fox medical drama '' House''. He is played by Robert Sean Leonard. The character first appears in the show's pilot episode when he introduces a medical case to Dr. Gregory House. Wilson is Dr. House's only true friend, and frequently provides him with consultations and aid. Wilson is the head of the Department of Oncology at Princeton- Plainsboro Teaching Hospital. During the show's run, the characters of House and Wilson have been compared to Sherlock Holmes and Dr Watson. Wilson's portrayer, Robert Sean Leonard, has stated that his character and Dr. House were originally supposed to play these roles; but Dr. House's diagnostic team has taken over Dr. Wilson's part. Leonard also read the script of the pilot episode of CBS' ''Numb3rs'' and was planning to audition. He auditioned for Wilson instead because he felt he would more enjoy playing the character that House went to for help and because he liked the '' Odd Couple' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lisa Cuddy
Lisa Cuddy, M.D., is a fictional character on the Fox medical drama ''House''. She is portrayed by Lisa Edelstein. Cuddy was the Dean of Medicine of the fictional Princeton-Plainsboro Teaching Hospital in New Jersey. Cuddy quit her job after the events of season seven's finale " Moving On". Storylines Cuddy's job title in ''House'' is Dean of Medicine and Hospital Administrator. She is Jewish, and has a mother and one sister; her father is dead. She began dreaming of becoming a doctor when she was 12, graduated from medical school at age 25 as second best in her class, and became the first female and second youngest Dean of Medicine at the age of 32 (she was actually 29 but she added three years to her age in order to seem more mature to the Selection Committee). Cuddy attended the University of Michigan, where she first met Gregory House (Hugh Laurie), and with whom she shared a one-night stand. After hiring House to run the hospital's Diagnostics Department, Cuddy began setting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
