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Simon Fishel
Simon Fishel (born 29 July 1953) is an English physiologist, biochemist and pioneering ''in vitro'' fertilisation (IVF) specialist. Fishel joined Robert Edwards in 1975 and eventually worked alongside Edwards and Patrick Steptoe, the duo that successfully pioneered conception through IVF, leading to the birth of Louise Brown on 25 July 1978. Early life and education Simon Brian Fishel was born to a Jewish family in Liverpool and grew up close to Calderstones Park. His father, Joseph, was a tailor and his mother, Jane, was one of 12 siblings from a family of Eastern European refugees. Fishel was educated at King David High School, Liverpool, where he became Head Boy. After securing A-Levels, Fishel initially taught at a school in Speke, on the outskirts of Liverpool. He then studied Physiology and Biochemistry at the University of Salford, graduating in 1975 with double first-class BSc Honours. Fishel moved to the University of Cambridge after being appointed to a PhD posit ...
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Liverpool
Liverpool is a city and metropolitan borough in Merseyside, England. With a population of in 2019, it is the 10th largest English district by population and its metropolitan area is the fifth largest in the United Kingdom, with a population of 2.24 million. On the eastern side of the Mersey Estuary, Liverpool historically lay within the ancient hundred of West Derby in the county of Lancashire. It became a borough in 1207, a city in 1880, and a county borough independent of the newly-created Lancashire County Council in 1889. Its growth as a major port was paralleled by the expansion of the city throughout the Industrial Revolution. Along with general cargo, freight, and raw materials such as coal and cotton, merchants were involved in the slave trade. In the 19th century, Liverpool was a major port of departure for English and Irish emigrants to North America. It was also home to both the Cunard and White Star Lines, and was the port of registry of the ocean li ...
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King David High School, Liverpool
King David High School is a mixed voluntary aided Jewish ethos-based secondary school located in the Wavertree district of Liverpool, England. It provides Jewish education, but also admits and caters to students of other faiths. Facilities In September 2011, the primary and secondary moved into a new school building, as part of the Building Schools for the Future (BSF) programme. There are three floors in King David. On the ground floor, there are the "creative" subjects, including ICT, business, art, design technology, and PE. There is also the reception area, sixth form common room, and atrium. On the first floor, there are the humanities subjects (English, modern foreign languages, history, and geography). The second floor is the home to the mathematics rooms and science labs. All floors have "breakout" spaces, where classes can go to do project/group work. There are also ICT facilities, toilets, and water fountains on each floor. Notable alumni * Ian Broudie, singer-songwr ...
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Growth Medium
A growth medium or culture medium is a solid, liquid, or semi-solid designed to support the growth of a population of microorganisms or cells via the process of cell proliferation or small plants like the moss ''Physcomitrella patens''. Different types of media are used for growing different types of cells. The two major types of growth media are those used for cell culture, which use specific cell types derived from plants or animals, and those used for microbiological culture, which are used for growing microorganisms such as bacteria or fungi. The most common growth media for microorganisms are nutrient broths and agar plates; specialized media are sometimes required for microorganism and cell culture growth. Some organisms, termed fastidious organisms, require specialized environments due to complex nutritional requirements. Viruses, for example, are obligate intracellular parasites and require a growth medium containing living cells. Types The most common growth media ...
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Petri Dish
A Petri dish (alternatively known as a Petri plate or cell-culture dish) is a shallow transparent lidded dish that biologists use to hold growth medium in which cells can be cultured,R. C. Dubey (2014): ''A Textbook Of Biotechnology For Class-XI'', 4th edition, p. 469. originally, cells of bacteria, fungi and small mosses. The container is named after its inventor, German bacteriologist Julius Richard Petri. It is the most common type of culture plate. The Petri dish is one of the most common items in biology laboratories and has entered popular culture. The term is sometimes written in lower case, especially in non-technical literature. What was later called Petri dish was originally developed by German physician Robert Koch in his private laboratory in 1881, as a precursor method. Petri, as assistant to Koch, at Berlin University made the final modifications in 1887 as used today. Penicillin, the first antibiotic, was discovered in 1929 when Alexander Fleming noticed that m ...
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Test Tube
A test tube, also known as a culture tube or sample tube, is a common piece of laboratory glassware consisting of a finger-like length of glass or clear plastic tubing, open at the top and closed at the bottom. Test tubes are usually placed in special-purpose test tube rack, racks. Types and usage Chemistry Test tubes intended for general chemical work are usually made of glass, for its relative resistance to heat. Tubes made from expansion-resistant glasses, mostly borosilicate glass or fused quartz, can withstand high temperatures up to several hundred degrees Celsius. Chemistry tubes are available in a multitude of lengths and widths, typically from 10 to 20 mm wide and 50 to 200 mm long. The top often features a flared lip to aid pouring out the contents. A chemistry test tube typically has a flat bottom, a round bottom, or a conical bottom. Some test tubes are made to accept a ground glass joint, ground glass stopper or a screw cap. They are often provided w ...
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Human Reproduction (journal)
''Human Reproduction'' is a peer-reviewed scientific journal covering all aspects of human reproduction, including reproductive physiology and pathology, endocrinology, andrology, gonad function, gametogenesis, fertilization, embryo development, implantation, pregnancy, genetics, preimplantation genetic diagnosis, oncology, infectious disease, surgery, contraception, infertility treatment, psychology, ethics, and social issues. It is an official journal of the European Society of Human Reproduction and Embryology. It was established in 1986 with Robert Edwards as founding editor-in-chief. Spin-off journals The journals ''Human Reproduction Update'' and ''Molecular Human Reproduction'' are spin-offs from ''Human Reproduction'' that were established in 1995. The main journal concentrates on original research, clinical case studies, as well as opinions and debates on topical issues. ''Human Reproduction Update'' is a bimonthly review journal. According to the Journal Citation Rep ...
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European Society Of Human Reproduction And Embryology
The European Society of Human Reproduction and Embryology (ESHRE) was founded in 1985 by Robert Edwards (University of Cambridge) and J. Cohen (Paris), who felt that the study and research in the field of reproduction needed to be encouraged and recognized. It is currently headquartered in Belgium. Aims The aims of the society are: * to promote the understanding of reproductive biology and embryology * to facilitate research and the subsequent dissemination of research findings to the public, scientists, clinicians and patient associations * to inform politicians and policy makers in Europe. The society further engages in medical education activities, the development of data registries, and the implementation of methods to improve safety and quality in clinical and laboratory procedures. Structure The society consists of: * General Assembly, comprising all its members, made up of diverse sub-special interest groups, such as andrology, reproductive genetics, ethics and law, an ...
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John Webster (doctor)
John Webster (c. 1580 – c. 1632) was an English Jacobean dramatist best known for his tragedies ''The White Devil'' and ''The Duchess of Malfi'', which are often seen as masterpieces of the early 17th-century English stage. His life and career overlapped with Shakespeare's. Biography Webster's life is obscure and the dates of his birth and death are not known. His father, a carriage maker also named John Webster, married a blacksmith's daughter named Elizabeth Coates on 4 November 1577 and it is likely that Webster was born not long after, in or near London. The family lived in St Sepulchre's parish. His father John and uncle Edward were Freemen of the Merchant Taylors' Company and Webster attended Merchant Taylors' School in Suffolk Lane, London. On 1 August 1598, "John Webster, lately of the New Inn" was admitted to the Middle Temple, one of the Inns of Court; in view of the legal interests evident in his dramatic work, this may be the playwright. Webster married 17-year-ol ...
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Bourn Hall Clinic
Bourn Hall Clinic in Bourn, Cambridgeshire, England, is a centre for the treatment of infertility. The original building, Bourn Hall, is about 400 years old. Since becoming a medical centre, it has been greatly extended. History Bourn Hall Clinic was founded in 1980 by IVF pioneers Mr Patrick Steptoe, embryologist Jean Purdy and Professor Robert Edwards, who were responsible for the conception of Louise Brown, the world's first IVF or test-tube baby in 1977. Since its foundation the clinic has assisted in the conception of over 10,000 babies. Following the death of Patrick Steptoe in 1988, Peter Brinsden was appointed Medical Director in March 1989. Bourn Hall Clinic is one of five fertility centres selected by the NHS East of England Specialised Commissioning Group to provide treatment to patients in the region. As of 1 May 2009, childless couples in Cambridgeshire, Norfolk, Suffolk, Essex, Bedfordshire and Hertfordshire will be able to access up to three cycles of IVF, pl ...
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Infertility
Infertility is the inability of a person, animal or plant to reproduce by natural means. It is usually not the natural state of a healthy adult, except notably among certain eusocial species (mostly haplodiploid insects). It is the normal state of a human child or other young offspring, because they have not undergone puberty, which is the body's start of reproductive capacity. In humans, infertility is the inability to become pregnant after one year of unprotected and regular sexual intercourse involving a male and female partner.Chowdhury SH, Cozma AI, Chowdhury JH. Infertility. Essentials for the Canadian Medical Licensing Exam: Review and Prep for MCCQE Part I. 2nd edition. Wolters Kluwer. Hong Kong. 2017. There are many causes of infertility, including some that medical intervention can treat. Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem with infertility. Many more couples, however, experience involu ...
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Oldham
Oldham is a large town in Greater Manchester, England, amid the Pennines and between the rivers Irk and Medlock, southeast of Rochdale and northeast of Manchester. It is the administrative centre of the Metropolitan Borough of Oldham, which had a population of 237,110 in 2019. Within the boundaries of the historic county of Lancashire, and with little early history to speak of, Oldham rose to prominence in the 19th century as an international centre of textile manufacture. It was a boomtown of the Industrial Revolution, and among the first ever industrialised towns, rapidly becoming "one of the most important centres of cotton and textile industries in England." At its zenith, it was the most productive cotton spinning mill town in the world,. producing more cotton than France and Germany combined. Oldham's textile industry fell into decline in the mid-20th century; the town's last mill closed in 1998. The demise of textile processing in Oldham depressed and heavily ...
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Beit Memorial Fellowships For Medical Research
The Beit Memorial Medical Fellowships were one of the most prestigious and competitive fellowships for post-doctoral or medical degree research in medicine in the United Kingdom. The Fellowships were founded in 1909 by Sir Otto Beit, a German-born British financier, philanthropist and art connoisseur, in memory of his brother Alfred Beit. Beit Memorial Fellows have been awarded a number of prestigious prizes with seven Nobel Prizes including two for Frederick Sanger (1944) and the 2012 prize for medicine for John Gurdon. Nobel laureates who have held Beit fellowships are Alexander R. Todd (chemistry, 1957), Fred Sanger (chemistry, 1958 and 1980), Macfarlane Burnet (physiology or medicine, 1960), Bernard Katz (physiology or medicine, 1970) and Tim Hunt (physiology or medicine, 2001). The first female member of the Royal Society in 1945 was Marjory Stephenson (1914 Beit fellowship) an early recipient of the fellowship. The Beit Memorial Medical Fellowships were replaced by the prest ...
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