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Sigma-Aldrich
Sigma-Aldrich (formally MilliporeSigma) is an American chemical, life science, and biotechnology company that is owned by the German chemical conglomerate Merck Group. Sigma-Aldrich was created in 1975 by the merger of Sigma Chemical Company and Aldrich Chemical Company. It grew through various acquisitions until it had over 9,600 employees and was listed on the Fortune 1000. The company is headquartered in St. Louis and has operations in approximately 40 countries. In 2015, the German chemical conglomerate Merck Group acquired Sigma-Aldrich for $17 billion. The company is currently a part of Merck's life science business and in combination with Merck's earlier acquired Millipore Corporation, Millipore, operates as MilliporeSigma. History Sigma Chemical Company of St. Louis and Aldrich Chemical Company of Milwaukee were both American specialty chemical companies when they merged in August 1975. The company grew throughout the 1980s and 1990s, with significant expansion in fac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck Group
The Merck Group, branded and commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and present in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies in the world. Merck operates in Europe, Africa, Asia, Oceania and the Americas. It has major research and development centres in Darmstadt, Boston, Tokyo and Beijing, as well as other Research and Development units in Taiwan, France, Israel, South Korea, India and in the UK. Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine. Merck was privately owned until going public on the Frankfurt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck KGaA
The Merck Group, branded and commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and present in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies in the world. Merck operates in Europe, Africa, Asia, Oceania and the Americas. It has major research and development centres in Darmstadt, Boston, Tokyo and Beijing, as well as other Research and Development units in Taiwan, France, Israel, South Korea, India and in the UK. Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine. Merck was privately owned until going public on the Frankfurt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Millipore Corporation
Merck Millipore was the brand used by Merck Group's (not US-based Merck & Co.) global life science business until 2015 when the company re-branded. It was formed when Merck acquired the Millipore Corporation in 2010. Merck is a supplier to the life science industry. The Millipore Corporation was founded in 1954, and listed among the S&P 500 since the early 1990s, as an international biosciences company which makes micrometer pore-size filters and tests. In 2015, Merck acquired Sigma-Aldrich and merged it with Merck Millipore. In the United States and Canada, the life science business is now known as MilliporeSigma. History Founding In the early 1950s, Lovell Corporation won a contract from the U.S. Army Chemical Engineers to develop and manufacture membrane filtering devices used to separate the molecular components of fluid samples. When the membranes were declassified in 1953 and offered for commercial use, Jack Bush, son of Vannevar Bush and a Lovell employee, bought the co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfred Bader
Alfred Robert Bader, CBE (April 28, 1924 – December 23, 2018) was a Canadian chemist, businessman, philanthropist, and collector of fine art. He was considered by the '' Chemical & Engineering News'' poll of 1998 to be one of the "Top 75 Distinguished Contributors to the Chemical Enterprise" during C&EN's 75-year history. Early years Alfred Bader was born on April 28, 1924, in Vienna, Austria. His father, Alfred Bader, was of Czech Jewish descent. His grandfather, Moritz Ritter von Bader, had been a civil engineer, who worked on the Suez Canal and was knighted by Emperor Franz Josef for his service as Austrian consul at Ismaïlia. His mother, Elizabeth Countess Serényi, came from an aristocratic Catholic Hungarian family. In spite of adamant opposition from Serényi's family, the couple had married in London and settled in Vienna. Alfred was born only two weeks before his father's death. He was adopted by his father's sister, Gisela Reich, and raised as a Jew. His older ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fine Chemicals
In chemistry, fine chemicals are complex, single, pure chemical substances, produced in limited quantities in multipurpose plants by multistep batch chemical or biotechnological processes. They are described by exacting specifications, used for further processing within the chemical industry and sold for more than $10/kg (see the comparison of fine chemicals, commodities and specialties). The class of fine chemicals is subdivided either on the basis of the added value (building blocks, advanced intermediates or active ingredients), or the type of business transaction, namely standard or exclusive products. Fine chemicals are produced in limited volumes ( $10/kg) according to exacting specifications, mainly by traditional organic synthesis in multipurpose chemical plants. Biotechnical processes are gaining ground. Fine chemicals are used as starting materials for specialty chemicals, particularly pharmaceuticals, biopharmaceuticals and agrochemicals. Custom manufacturin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The RNAi Consortium
The RNAi Consortium, or TRC, is a public-private partnership whose mission is to create libraries of small hairpin RNAs (shRNAs) for 15'000 human and 15'000 mouse genes. These libraries should help the scientific community to analyse gene function by RNAi. The consortium is based at the Broad Institute of the MIT and Harvard University, and includes 6 MIT- and Harvard-associated institutions and 5 international life sciences organizations. Verified RNAi clones and entire libraries are made available both by Sigma-Aldrich and Open Biosystems. Hairpin selection A set of candidate hairpins are selected based on the 1sRefseq transcript from each NCBI gene. They should be 21mers, be at least 25bp from start of the coding sequence and no closer than 150bp from its end. Candidates are scored based on various empirical rules (see the Broad Institute's web site for a complete lis and then BLASTed against 2 transcriptome sets. Hairpins that are unique for a Unigene cluster and a RefSeq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St Louis
St. Louis () is the second-largest city in Missouri, United States. It sits near the confluence of the Mississippi and the Missouri Rivers. In 2020, the city proper had a population of 301,578, while the bi-state metropolitan area, which extends into Illinois, had an estimated population of over 2.8 million, making it the largest metropolitan area in Missouri and the second-largest in Illinois. Before European settlement, the area was a regional center of Native American Mississippian culture. St. Louis was founded on February 14, 1764, by French fur traders Gilbert Antoine de St. Maxent, Pierre Laclède and Auguste Chouteau, who named it for Louis IX of France. In 1764, following France's defeat in the Seven Years' War, the area was ceded to Spain. In 1800, it was retroceded to France, which sold it three years later to the United States as part of the Louisiana Purchase; the city was then the point of embarkation for the Corps of Discovery on the Lewis and Clark Expe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aldrich Logo
Aldrich may refer to: Places United States * Aldrich, Alabama, unincorporated community * Aldrich, Minnesota, city * Aldrich Township, Wadena County, Minnesota * Aldrich, Missouri, village People * Aldrich (surname), a surname (including a list of people with the surname) People with the given name *Aldrich Ames (born 1941), American intelligence officer convicted of spying for the Soviet Union and Russia * Aldrich Robert Burgess (1918–1983), American film director Other uses *Aldrich, subsidiary of Sigma-Aldrich#Aldrich; a life science and high technology company *Aldrich Killian Aldrich Killian is a supervillain appearing in American comic books published by Marvel Comics. The character first appeared in '' Iron Man'' vol. 4 #1 (Jan. 2005) and was created by Warren Ellis and Adi Granov. Guy Pearce portrayed a retooled ..., fictional Marvel Comics supervillain * Aldrich, Devourer of Gods, an antagonist in the video game ''Dark Souls III'' {{disambiguation, geo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isotopes
Isotopes are two or more types of atoms that have the same atomic number (number of protons in their nuclei) and position in the periodic table (and hence belong to the same chemical element), and that differ in nucleon numbers (mass numbers) due to different numbers of neutrons in their nuclei. While all isotopes of a given element have almost the same chemical properties, they have different atomic masses and physical properties. The term isotope is formed from the Greek roots isos ( ἴσος "equal") and topos ( τόπος "place"), meaning "the same place"; thus, the meaning behind the name is that different isotopes of a single element occupy the same position on the periodic table. It was coined by Scottish doctor and writer Margaret Todd in 1913 in a suggestion to the British chemist Frederick Soddy. The number of protons within the atom's nucleus is called its atomic number and is equal to the number of electrons in the neutral (non-ionized) atom. Each atomic numb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Avista Capital Partners
Avista Capital Partners is an American private equity firm headquartered in New York City focused on growth capital and leveraged buyout investments in middle-market companies in the domestic healthcare sector. History The firm was founded in 2005 by Steven Webster, Thompson Dean and David Burgstahler, as a spinoff from Credit Suisse's private equity arm DLJ Merchant Banking Partners (Dean was head of DLJMBP). Avista's spinoff from Credit Suisse was at the same time as private equity groups from other leading investment banks were formed including JPMorgan Chase's CCMP Capital, Citigroup's Court Square Capital Partners, Deutsche Bank's MidOcean Partners, and Morgan Stanley's Metalmark Capital. In 2007, the firm closed its first fund at $2 billion. This included a commitment from predecessor Credit Suisse, whereas fellow spin-off Diamond Castle did not. Avista’s second fund closed with $1.8 billion of commitments, which was lower than its original target between $2.5 and $3 bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reagents
In chemistry, a reagent ( ) or analytical reagent is a substance or compound added to a system to cause a chemical reaction, or test if one occurs. The terms ''reactant'' and ''reagent'' are often used interchangeably, but reactant specifies a substance ''consumed'' in the course of a chemical reaction. ''Solvents'', though involved in the reaction mechanism, are usually not called reactants. Similarly, '' catalysts'' are not consumed by the reaction, so they are not reactants. In biochemistry, especially in connection with enzyme-catalyzed reactions, the reactants are commonly called substrates. Definitions Organic chemistry In organic chemistry, the term "reagent" denotes a chemical ingredient (a compound or mixture, typically of inorganic or small organic molecules) introduced to cause the desired transformation of an organic substance. Examples include the Collins reagent, Fenton's reagent, and Grignard reagents. Analytical chemistry In analytical chemistry, a reage ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Synthesis
As a topic of chemistry, chemical synthesis (or combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds (known as '' reagents'' or ''reactants'') that will experience a transformation when subjected to certain conditions. Various reaction types can be applied to formulate a desired product. This requires mixing the compounds in a reaction vessel, such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of processing (" work-up") or purification procedure to isolate the final product. The amount produced by chemical synthesis is known as the ''reaction yield''. Typically, yields are expressed as a mass in grams (in a laboratory setting) or as a percentage of the total theoretical quantity ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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