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Siamon Gordon
Siamon Gordon (born 29 April 1938) is a British pathologist. He is Glaxo Wellcome Professor Emeritus of Cellular Pathology at the University of Oxford. Education He gained his medical degrees ( M.B. and Ch.B.) from the University of Cape Town, South Africa. He earned his PhD from Rockefeller University, where he taught from 1971 to 1976. The rest of his career, from 1976 to 2008, was at the University of Oxford. Career and research He was on the Faculty of 1000. He was a visiting scientist at the NIH. He is on the Scientific Advisory Board of the American Asthma Foundation. Gordon is noted for his work on the phenotypic and functional diversity of macrophages. He began his studies on macrophages while in the laboratory of Zanvil Cohn at Rockefeller University in 1966. Upon his move to the Sir William Dunn School of Pathology at University of Oxford in 1976 he continued this work and identified the pan-macrophage marker F4/80. Subsequent studies led to the identification of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jonathan Austyn
Jonathan M. Austyn is Professor of Immunobiology at the University of Oxford and a Fellow of Wolfson College, Oxford. He has taught immunology over many years, and designed the Master of Science course in Integrated Immunology at the University of Oxford, which he co-directs. Education Austyn was educated at the University of Oxford where he was awarded a Doctor of Philosophy degre in for research investigating monoclonal antibodies against the murine macrophage supervised by Siamon Gordon. Career and research Austyn has over 25 years research experience of dendritic cell immunology, particularly as applied to transplantation, infectious diseases and cancer. With Gordon MacPherson he co-authored the textbook ''Exploring Immunology: Concepts and Evidence''. Awards and honours Austyn was awarded with distinction the Diploma in Learning and Teaching in Higher Education Higher education is tertiary education leading to award of an academic degree. Higher education, al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sir William Dunn School Of Pathology
The Sir William Dunn School of Pathology is a department within the University of Oxford. Its research programme includes the cellular and molecular biology of pathogens, the immune response, cancer and cardiovascular disease. It teaches undergraduate and graduate courses in the medical sciences. The school is named for Sir William Dunn, 1st Baronet, of Lakenheath, whose will provided the initial funding. It is located towards the east end of South Parks Road, to the north of the city centre. __TOC__ History The first course of Pathology teaching in the University of Oxford was given in 1894 by Professor John Burdon Sanderson, Professor of Physiology, (Regius Professor of Medicine from 1895 to 1905), and Dr James Ritchie, who, in 1897, was appointed as the first University Lecturer in Pathology. The first Department of Pathology was opened in 1901 and functioned until 1927 when it was handed over to Pharmacology on completion of the new purpose-built Sir William Dunn School of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rockefeller University Alumni
Rockefeller is a German surname, originally given to people from the village of Rockenfeld near Neuwied in the Rhineland and commonly referring to subjects associated with the Rockefeller family. It may refer to: People with the name Rockefeller family *John D. Rockefeller Sr. (1839–1937), founder of the Standard Oil Company *Laura Spelman Rockefeller (1839–1915), wife of John D.R., namesake of Spelman College *William Rockefeller (1841–1922), brother of John D.R. * Bessie Rockefeller Strong (1866–1906), daughter of John D.R. * Alice Rockefeller (1869–1870), daughter of John D.R. * Alta Rockefeller Prentice (1871–1962), daughter of John D.R., founder Alta House (settlement house) *Edith Rockefeller McCormick (1872–1932), daughter of John D.R., feminist, philanthropist *John D. Rockefeller Jr. (Junior) (1874–1960), son of Senior *Abby Aldrich Rockefeller (1874–1948), wife of Junior *Percy Avery Rockefeller (1878–1934), son of William * Margaret Rockefeller Strong ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cape Town Alumni
A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, the designation is reserved for colleges that have a graduate school. The word ''university'' is derived from the Latin ''universitas magistrorum et scholarium'', which roughly means "community of teachers and scholars". The first universities were created in Europe by Catholic Church monks. The University of Bologna (''Università di Bologna''), founded in 1088, is the first university in the sense of: *Being a high degree-awarding institute. *Having independence from the ecclesiastic schools, although conducted by both clergy and non-clergy. *Using the word ''universitas'' (which was coined at its foundation). *Issuing secular and non-secular degrees: grammar, rhetoric, logic, theology, canon law, notarial law.Hunt Janin: "The university i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statutory Professors Of The University Of Oxford
A statute is a formal written enactment of a legislative authority that governs the legal entities of a city, state, or country by way of consent. Typically, statutes command or prohibit something, or declare policy. Statutes are rules made by legislative bodies; they are distinguished from case law or precedent, which is decided by courts, and regulations issued by government agencies. Publication and organization In virtually all countries, newly enacted statutes are published and distributed so that everyone can look up the statutory law. This can be done in the form of a government gazette which may include other kinds of legal notices released by the government, or in the form of a series of books whose content is limited to legislative acts. In either form, statutes are traditionally published in chronological order based on date of enactment. A universal problem encountered by lawmakers throughout human history is how to organize published statutes. Such publications ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of The Academy Of Medical Sciences (United Kingdom)
{{disambiguation ...
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses *Fellows Auctioneers, established in 1876. *Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathematics, engineering science, and medical science". Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki Ramakrishnan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of Exeter College, Oxford
{{disambiguation ...
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places *Fellows, California, USA *Fellows, Wisconsin, ghost town, USA Other uses *Fellows Auctioneers, established in 1876. *Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton *Fellows (surname) See also *North Fellows Historic District, listed on the National Register of Historic Places in Wapello County, Iowa *Justice Fellows (other) Justice Fellows may refer to: * Grant Fellows (1865–1929), associate justice of the Michigan Supreme Court * Raymond Fellows (1885–1957), associate justice of the Maine Supreme Judicial Court {{disambiguation, tndis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Pathologists
British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, the English language as spoken and written in the United Kingdom or, more broadly, throughout the British Isles * Celtic Britons, an ancient ethno-linguistic group * Brittonic languages, a branch of the Insular Celtic language family (formerly called British) ** Common Brittonic, an ancient language Other uses *''Brit(ish)'', a 2018 memoir by Afua Hirsch *People or things associated with: ** Great Britain, an island ** United Kingdom, a sovereign state ** Kingdom of Great Britain (1707–1800) ** United Kingdom of Great Britain and Ireland (1801–1922) See also * Terminology of the British Isles * Alternative names for the British * English (other) * Britannic (other) * British Isles * Brit (other) * Briton (d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pattern Recognition Receptor
Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which detect molecules typical for the pathogens. They are proteins expressed, mainly, by cells of the innate immune system, such as dendritic cells, macrophages, monocytes, neutrophils and epithelial cells, to identify two classes of molecules: pathogen-associated molecular patterns (PAMPs), which are associated with microbial pathogens, and damage-associated molecular patterns (DAMPs), which are associated with components of host's cells that are released during cell damage or death. They are also called primitive pattern recognition receptors because they evolved before other parts of the immune system, particularly before adaptive immunity. PRRs also mediate the initiation of antigen-specific adaptive immune response and release of inflammatory cytokines. The microbe-specific molecules that are recognized by a given PRR are called p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cloning
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of Cell (biology), cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
F4/80
EGF-like module-containing mucin-like hormone receptor-like 1 also known as F4/80 is a protein encoded by the ''ADGRE1'' gene. EMR1 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain. EMR1 expression in human is restricted to eosinophils and is a specific marker for these cells. The murine homolog of EMR1, F4/80, is a well-known and widely used marker of murine macrophage populations. The N-terminal fragment (NTF) of EMR1 contains 4-6 Epidermal Growth Factor-like (EGF-like) domains in human and 4-7 EGF-like domains in the mouse. Function Utilizing F4/80 knockout mice, Lin et al. showed that F4/80 is not necessary for the development of tissue macrophages but is required for the induction of efferent CD8+ regulatory T cells needed for peripheral tolerance. Clinical significa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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