Scintillography
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Scintillography
Scintigraphy (from Latin ''scintilla'', "spark"), also known as a gamma scan, is a diagnostic test in nuclear medicine, where radioisotopes attached to drugs that travel to a specific organ or tissue (radiopharmaceuticals) are taken internally and the emitted gamma radiation is captured by external detectors (gamma cameras) to form two-dimensional images in a similar process to the capture of x-ray images. In contrast, SPECT and '' positron emission tomography'' (PET) form 3-dimensional images and are therefore classified as separate techniques from scintigraphy, although they also use gamma cameras to detect internal radiation. Scintigraphy is unlike a diagnostic X-ray where external radiation is passed through the body to form an image. Process Scintillography is an imaging method of nuclear events provoked by collisions or charged current interactions among nuclear particles or ionizing radiation and atoms which result in a brief, localised pulse of electromagnetic radiati ...
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Positron Emission Tomography
Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in Metabolism, metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption. Different tracers are used for various imaging purposes, depending on the target process within the body. For example, 18F-FDG, -FDG is commonly used to detect cancer, Sodium fluoride#Medical imaging, NaF is widely used for detecting bone formation, and Isotopes of oxygen#Oxygen-15, oxygen-15 is sometimes used to measure blood flow. PET is a common medical imaging, imaging technique, a Scintigraphy#Process, medical scintillography technique used in nuclear medicine. A radiopharmaceutical, radiopharmaceutical — a radioisotope attached to a drug — is injected into the body as a radioactive tracer, tracer. When the radiopharmaceutical undergoes beta plus decay, a positron is ...
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Nuclear Medicine
Nuclear medicine or nucleology is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging, in a sense, is "radiology done inside out" because it records radiation emitting from within the body rather than radiation that is generated by external sources like X-rays. In addition, nuclear medicine scans differ from radiology, as the emphasis is not on imaging anatomy, but on the function. For such reason, it is called a physiological imaging modality. Single photon emission computed tomography (SPECT) and positron emission tomography (PET) scans are the two most common imaging modalities in nuclear medicine. Diagnostic medical imaging Diagnostic In nuclear medicine imaging, radiopharmaceuticals are taken internally, for example, through inhalation, intravenously or orally. Then, external detectors (gamma cameras) capture and form images from the radiation emitted by the radiopharmaceuticals. This process ...
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Medical Imaging
Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging. Measurement and recording techniques that are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), electrocardiography (ECG), and others, represent other technologies that produce data susceptible to representation as a parameter graph versus time or maps that contain data about the measurement loca ...
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Neutrino
A neutrino ( ; denoted by the Greek letter ) is a fermion (an elementary particle with spin of ) that interacts only via the weak interaction and gravity. The neutrino is so named because it is electrically neutral and because its rest mass is so small ('' -ino'') that it was long thought to be zero. The rest mass of the neutrino is much smaller than that of the other known elementary particles excluding massless particles. The weak force has a very short range, the gravitational interaction is extremely weak due to the very small mass of the neutrino, and neutrinos do not participate in the strong interaction. Thus, neutrinos typically pass through normal matter unimpeded and undetected. Weak interactions create neutrinos in one of three leptonic flavors: electron neutrinos muon neutrinos (), or tau neutrinos (), in association with the corresponding charged lepton. Although neutrinos were long believed to be massless, it is now known that there are three discrete ...
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Tetrachloroethylene
Tetrachloroethylene, also known under the systematic name tetrachloroethene, or perchloroethylene, and many other names (and abbreviations such as "perc" or "PERC", and "PCE"), is a chlorocarbon with the formula Cl2C=CCl2 . It is a colorless liquid widely used for dry cleaning of fabrics, hence it is sometimes called "dry-cleaning fluid". It also has its uses as an effective automotive brake cleaner. It has a sweet odor detectable by most people at a concentration of 1 part per million (1 ppm). Worldwide production was about in 1985.M. Rossberg et al. "Chlorinated Hydrocarbons" in ''Ullmann's Encyclopedia of Industrial Chemistry'', 2006, Wiley-VCH, Weinheim. Production British physicist and chemist Michael Faraday first synthesized tetrachloroethylene in 1821 by thermal decomposition of hexachloroethane. :C2Cl6 → C2Cl4 + Cl2 Most tetrachloroethylene is produced by high temperature chlorinolysis of light hydrocarbons. The method is related to Faraday's discovery since hexachl ...
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Neutrino Detection
A neutrino detector is a physics apparatus which is designed to study neutrinos. Because neutrinos only weakly interact with other particles of matter, neutrino detectors must be very large to detect a significant number of neutrinos. Neutrino detectors are often built underground, to isolate the detector from cosmic rays and other background radiation. The field of neutrino astronomy is still very much in its infancy – the only confirmed extraterrestrial sources are the Sun and the supernova 1987A in the nearby Large Magellanic Cloud. Another likely source (three standard deviations) is the blazar TXS 0506+056 about 3.7 billion light years away. Neutrino observatories will "give astronomers fresh eyes with which to study the universe". Various detection methods have been used. Super Kamiokande is a large volume of water surrounded by phototubes that watch for the Cherenkov radiation emitted when an incoming neutrino creates an electron or muon in the water. The Sudbur ...
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Experimental Physics
Experimental physics is the category of disciplines and sub-disciplines in the field of physics that are concerned with the observation of physical phenomena and experiments. Methods vary from discipline to discipline, from simple experiments and observations, such as Galileo's experiments, to more complicated ones, such as the Large Hadron Collider. Overview Experimental physics encompasses all the disciplines of physics that are concerned with data acquisition, data-acquisition methods, and the detailed conceptualization (beyond simple thought experiments) and realization of laboratory experiments. It is often contrasted with theoretical physics, which is more concerned with predicting and explaining the physical behaviour of nature than the acquisition of empirical data. Although experimental and theoretical physics are concerned with different aspects of nature, they both share the same goal of understanding it and have a symbiotic relationship. The former provides data a ...
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Scintillation Camera
A gamma camera (γ-camera), also called a scintillation camera or Anger camera, is a device used to image gamma radiation emitting radioisotopes, a technique known as scintigraphy. The applications of scintigraphy include early drug development and nuclear medical imaging to view and analyse images of the human body or the distribution of medically injected, inhaled, or ingested radionuclides emitting gamma rays. Imaging techniques Scintigraphy ("scint") is the use of gamma cameras to capture emitted radiation from internal radioisotopes to create two-dimensional images. SPECT (single photon emission computed tomography) imaging, as used in nuclear cardiac stress testing, is performed using gamma cameras. Usually one, two or three detectors or heads, are slowly rotated around the patient's torso. Multi-headed gamma cameras can also be used for positron emission tomography (PET) scanning, provided that their hardware and software can be configured to detect "coincidences" (nea ...
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Gamma Camera Cross Section
Gamma (uppercase , lowercase ; ''gámma'') is the third letter of the Greek alphabet. In the system of Greek numerals it has a value of 3. In Ancient Greek, the letter gamma represented a voiced velar stop . In Modern Greek, this letter represents either a voiced velar fricative or a voiced palatal fricative (while /g/ in foreign words is instead commonly transcribed as γκ). In the International Phonetic Alphabet and other modern Latin-alphabet based phonetic notations, it represents the voiced velar fricative. History The Greek letter Gamma Γ is a grapheme derived from the Phoenician letter (''gīml'') which was rotated from the right-to-left script of Canaanite to accommodate the Greek language's writing system of left-to-right. The Canaanite grapheme represented the /g/ phoneme in the Canaanite language, and as such is cognate with ''gimel'' ג of the Hebrew alphabet. Based on its name, the letter has been interpreted as an abstract representation of a camel's ...
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Region Of Interest
A region of interest (often abbreviated ROI) is a sample within a data set identified for a particular purpose. The concept of a ROI is commonly used in many application areas. For example, in medical imaging, the boundaries of a tumor may be defined on an image or in a volume, for the purpose of measuring its size. The endocardial border may be defined on an image, perhaps during different phases of the cardiac cycle, for example, end-systole and end-diastole, for the purpose of assessing cardiac function. In geographical information systems (GIS), a ROI can be taken literally as a polygonal selection from a 2D map. In computer vision and optical character recognition, the ROI defines the borders of an object under consideration. In many applications, symbolic (textual) labels are added to a ROI, to describe its content in a compact manner. Within a ROI may lie individual ''points of interest'' (POIs). Examples of regions of interest * 1D dataset: a time or frequency interval on ...
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