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Science In Canada
Science and technology in Canada consists of three distinct but closely related phenomena: * the diffusion of technology in Canada * scientific research in Canada * innovation, invention and industrial research in Canada In 2019, Canada spent approximately on domestic research and development, of which over $7 billion was provided by the federal and provincial governments. In 2018, Canada spent approximately C$34.5 billion on domestic research and development, of which around $2 billion was spent directly by the federal government in-house and an additional $5.7 billion was provided by provincial and federal sources in the form of grants. This investment corresponds to about 1.57% of Canada's gross domestic product, a decline from 1.72% in 2014. Canada was ranked 16th in the Global Innovation Index in 2022. , the country has produced fifteen Nobel laureates in physics, chemistry, and medicine, and was ranked fourth worldwide for scientific research qu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
STS-116 - P5 Truss Hand-off To ISS (NASA S116-E-05765)
STS-116 was a Space Shuttle mission to the International Space Station (ISS) flown by Space Shuttle '' Discovery''. ''Discovery'' lifted off on 9 December 2006 at 20:47:35 EST. A previous launch attempt on 7 December had been canceled due to cloud cover. It was the first night launch of a Space Shuttle since STS-113 in November 2002. The mission is also referred to as ISS-12A.1 by the ISS program. The main goals of the mission were delivery and attachment of the International Space Station's P5 truss segment, a major rewiring of the station's power system, and exchange of ISS Expedition 14 personnel. The shuttle landed at 17:32 EST on 22 December 2006 at Kennedy Space Center 98 minutes off schedule due to unfavorable weather conditions. This mission was particularly notable to Sweden, being the first spaceflight of a Scandinavian astronaut (Christer Fuglesang). STS-116 was the final scheduled Space Shuttle launch from Pad 39B as NASA reconfigured it for Ares I launches. The o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artificial Cardiac Pacemaker
An artificial cardiac pacemaker (or artificial pacemaker, so as not to be confused with the natural cardiac pacemaker) or pacemaker is a medical device that generates electrical impulses delivered by electrodes to the chambers of the heart either the upper atria, or lower ventricles to cause the targeted chambers to contract and pump blood. By doing so, the pacemaker regulates the function of the electrical conduction system of the heart. The primary purpose of a pacemaker is to maintain an adequate heart rate, either because the heart's natural pacemaker is not fast enough, or because there is a block in the heart's electrical conduction system. Modern pacemakers are externally programmable and allow a cardiologist, particularly a cardiac electrophysiologist, to select the optimal pacing modes for individual patients. Most pacemakers are on demand, in which the stimulation of the heart is based on the dynamic demand of the circulatory system. Others send out a fixed rate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
T-cell Receptor
The T-cell receptor (TCR) is a protein complex found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules. The binding between TCR and antigen peptides is of relatively low affinity and is degenerate: that is, many TCRs recognize the same antigen peptide and many antigen peptides are recognized by the same TCR. The TCR is composed of two different protein chains (that is, it is a heterodimer). In humans, in 95% of T cells the TCR consists of an alpha (α) chain and a beta (β) chain (encoded by '' TRA'' and ''TRB'', respectively), whereas in 5% of T cells the TCR consists of gamma and delta (γ/δ) chains (encoded by '' TRG'' and '' TRD'', respectively). This ratio changes during ontogeny and in diseased states (such as leukemia). It also differs between species. Orthologues of the 4 loci have been mapped in various species. Each locus can produce a vari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Site-directed Mutagenesis
Site-directed mutagenesis is a molecular biology method that is used to make specific and intentional mutating changes to the DNA sequence of a gene and any gene products. Also called site-specific mutagenesis or oligonucleotide-directed mutagenesis, it is used for investigating the structure and biological activity of DNA, RNA, and protein molecules, and for protein engineering. Site-directed mutagenesis is one of the most important laboratory techniques for creating DNA libraries by introducing mutations into DNA sequences. There are numerous methods for achieving site-directed mutagenesis, but with decreasing costs of oligonucleotide synthesis, artificial gene synthesis is now occasionally used as an alternative to site-directed mutagenesis. Since 2013, the development of the CRISPR/Cas9 technology, based on a prokaryotic viral defense system, has also allowed for the editing of the genome, and mutagenesis may be performed ''in vivo'' with relative ease. History Early attempt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. ''In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 ''Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in exp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cygnus X-1
Cygnus X-1 (abbreviated Cyg X-1) is a galactic X-ray source in the constellation Cygnus and was the first such source widely accepted to be a black hole. It was discovered in 1964 during a rocket flight and is one of the strongest X-ray sources detectable from Earth, producing a peak X-ray flux density of (). It remains among the most studied astronomical objects in its class. The compact object is now estimated to have a mass about 21.2 times the mass of the Sun and has been shown to be too small to be any known kind of normal star or other likely object besides a black hole. If so, the radius of its event horizon has "as upper bound to the linear dimension of the source region" of occasional X-ray bursts lasting only for about 1 ms. Cygnus X-1 belongs to a high-mass X-ray binary system, located about 2.22 kiloparsecs from the Sun, that includes a blue supergiant variable star designated HDE 226868, which it orbits at about 0.2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Black Hole
A black hole is a region of spacetime where gravitation, gravity is so strong that nothing, including light or other Electromagnetic radiation, electromagnetic waves, has enough energy to escape it. The theory of general relativity predicts that a sufficiently compact mass can deform spacetime to form a black hole. The boundary (topology), boundary of no escape is called the event horizon. Although it has a great effect on the fate and circumstances of an object crossing it, it has no locally detectable features according to general relativity. In many ways, a black hole acts like an ideal black body, as it reflects no light. Moreover, quantum field theory in curved spacetime predicts that event horizons emit Hawking radiation, with thermal radiation, the same spectrum as a black body of a temperature inversely proportional to its mass. This temperature is of the order of billionths of a kelvin for stellar black holes, making it essentially impossible to observe directly. Obje ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Multi-touch
In computing, multi-touch is technology that enables a surface (a touchpad or touchscreen) to recognize the presence of more than one somatosensory system, point of contact with the surface at the same time. The origins of multitouch began at CERN, MIT, University of Toronto, Carnegie Mellon University and Bell Labs in the 1970s. CERN started using multi-touch screens as early as 1976 for the controls of the Super Proton Synchrotron. Capacitive multi-touch displays were popularized by Apple Inc., Apple's iPhone in 2007. Plural-point awareness may be used to implement additional functionality, such as pinch to zoom or to activate certain subroutines attached to Gesture recognition, predefined gestures. Several uses of the term multi-touch resulted from the quick developments in this field, and many companies using the term to market older technology which is called ''gesture-enhanced single-touch'' or several other terms by other companies and researchers. Several other similar or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deep Learning
Deep learning (also known as deep structured learning) is part of a broader family of machine learning methods based on artificial neural networks with representation learning. Learning can be supervised, semi-supervised or unsupervised. Deep-learning architectures such as deep neural networks, deep belief networks, deep reinforcement learning, recurrent neural networks, convolutional neural networks and Transformers have been applied to fields including computer vision, speech recognition, natural language processing, machine translation, bioinformatics, drug design, medical image analysis, Climatology, climate science, material inspection and board game programs, where they have produced results comparable to and in some cases surpassing human expert performance. Artificial neural networks (ANNs) were inspired by information processing and distributed communication nodes in biological systems. ANNs have various differences from biological brains. Specifically, artificial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plate Tectonics
Plate tectonics (from the la, label=Late Latin, tectonicus, from the grc, τεκτονικός, lit=pertaining to building) is the generally accepted scientific theory that considers the Earth's lithosphere to comprise a number of large tectonic plates which have been slowly moving since about 3.4 billion years ago. The model builds on the concept of ''continental drift'', an idea developed during the first decades of the 20th century. Plate tectonics came to be generally accepted by geoscientists after seafloor spreading was validated in the mid to late 1960s. Earth's lithosphere, which is the rigid outermost shell of the planet (the crust and upper mantle), is broken into seven or eight major plates (depending on how they are defined) and many minor plates or "platelets". Where the plates meet, their relative motion determines the type of plate boundary: '' convergent'', '' divergent'', or ''transform''. Earthquakes, volcanic activity, mountain-building, and oceanic tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts Institute Of Technology
The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the most prestigious and highly ranked academic institutions in the world. Founded in response to the increasing industrialization of the United States, MIT adopted a European polytechnic university model and stressed laboratory instruction in applied science and engineering. MIT is one of three private land grant universities in the United States, the others being Cornell University and Tuskegee University. The institute has an urban campus that extends more than a mile (1.6 km) alongside the Charles River, and encompasses a number of major off-campus facilities such as the MIT Lincoln Laboratory, the Bates Center, and the Haystack Observatory, as well as affiliated laboratories such as the Broad and Whitehead Institutes. , 98 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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