Sci-Mate
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Sci-Mate
Sci-Mate was a proposal for an open collaboration of scientists using Web 2.0 software to address well known challenges in academic publishing and technology transfer. The site provided free access to a collection of Web 2.0 software applications intended to make it easier for researchers and developers to bring together the necessary knowledge, tools and people for productive research and/or development. A demo version of the site was launched in April 2009, which included software supporting Articles, Discussion, Embedding and Item Exchange. Prior to launch the site was reviewed by ''The Australian'' and on ABC's Future Tense program. More recently the site was described in the December 2009 issue of the European Journal of Immunology in the lead up to the 1st Virtual Immunology Conference (VIC 2010). The site's terms and conditions state that it is research, not profit, oriented, and is intended to be owned, controlled and run by its community of research scientist members. Ar ...
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Web 2
Web 2.0 (also known as participative (or participatory) web and social web) refers to websites that emphasize user-generated content, ease of use, participatory culture and interoperability (i.e., compatibility with other products, systems, and devices) for end users. The term was coined by Darcy DiNucci in 1999 and later popularized by Tim O'Reilly and Dale Dougherty at the first Web 2.0 Conference in 2004. Although the term mimics the numbering of software versions, it does not denote a formal change in the nature of the World Wide Web, but merely describes a general change that occurred during this period as interactive websites proliferated and came to overshadow the older, more static websites of the original Web. A Web 2.0 website allows users to interact and collaborate with each other through social media dialogue as creators of user-generated content in a virtual community. This contrasts the first generation of Web 1.0-era websites where people were limited to vie ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Open Content Projects
Open or OPEN may refer to: Music * Open (band), Australian pop/rock band * The Open (band), English indie rock band * ''Open'' (Blues Image album), 1969 * ''Open'' (Gotthard album), 1999 * ''Open'' (Cowboy Junkies album), 2001 * ''Open'' (YFriday album), 2001 * ''Open'' (Shaznay Lewis album), 2004 * ''Open'' (Jon Anderson EP), 2011 * ''Open'' (Stick Men album), 2012 * ''Open'' (The Necks album), 2013 * ''Open'', a 1967 album by Julie Driscoll, Brian Auger and the Trinity * ''Open'', a 1979 album by Steve Hillage * "Open" (Queensrÿche song) * "Open" (Mýa song) * "Open", the first song on The Cure album ''Wish'' Literature * ''Open'' (Mexican magazine), a lifestyle Mexican publication * ''Open'' (Indian magazine), an Indian weekly English language magazine featuring current affairs * ''OPEN'' (North Dakota magazine), an out-of-print magazine that was printed in the Fargo, North Dakota area of the U.S. * Open: An Autobiography, Andre Agassi's 2009 memoir Computin ...
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Academic Publishing
Academic publishing is the subfield of publishing which distributes academic research and scholarship. Most academic work is published in academic journal articles, books or theses. The part of academic written output that is not formally published but merely printed up or posted on the Internet is often called "grey literature". Most scientific and scholarly journals, and many academic and scholarly books, though not all, are based on some form of peer review or editorial refereeing to qualify texts for publication. Peer review quality and selectivity standards vary greatly from journal to journal, publisher to publisher, and field to field. Most established academic disciplines have their own journals and other outlets for publication, although many academic journals are somewhat interdisciplinary, and publish work from several distinct fields or subfields. There is also a tendency for existing journals to divide into specialized sections as the field itself becomes more spec ...
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Material Transfer Agreement
A material transfer agreement (MTA) is a contract that governs the transfer of tangible research materials between two organizations when the recipient intends to use it for his or her own research purposes. The MTA defines the rights of the provider and the rights and obligations of the recipient with respect to the materials and any progeny, derivatives, or modifications. Biological materials, such as reagents, cell lines, plasmids, and vectors, are the most frequently transferred materials, but MTAs may also be used for other types of materials, such as chemical compounds, mouse models, and even some types of software. MTA types Three types of MTAs are most common at academic institutions: transfer between academic or research institutions, transfer from academia to industry and transfer from industry to academia. Each calls for different terms and conditions. For simple transfers not involving intellectual property, in the US the National Institutes of Health The Nationa ...
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Technology Transfer
Technology transfer (TT), also called transfer of technology (TOT), is the process of transferring (disseminating) technology from the person or organization that owns or holds it to another person or organization, in an attempt to transform inventions and scientific outcomes into new products and services that benefit society. Technology transfer is closely related to (and may arguably be considered a subset of) knowledge transfer. A comprehensive definition of technology transfer today includes the notion of collaborative process as it became clear that global challenges could be resolved only through the development of global solutions. Knowledge and technology transfer plays a crucial role in connecting innovation stakeholders and moving inventions from creators to public and private users. Intellectual property (IP) is an important instrument of technology transfer, as it establishes an environment conducive to sharing research results and technologies. Analysis in 2003 showe ...
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Assays
An assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity. The measured entity is often called the analyte, the measurand, or the target of the assay. The analyte can be a drug, biochemical substance, chemical element or compound, or cell in an organism or organic sample. An assay usually aims to measure an analyte's intensive property and express it in the relevant measurement unit (e.g. molarity, density, functional activity in enzyme international units, degree of effect in comparison to a standard, etc.). If the assay involves exogenous reactants (the reagents), then their quantities are kept fixed (or in excess) so that the quantity and quality of the target are the only limiting factors. The difference in the assay outcome is used to deduce the unknown quality or quantity of ...
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Animal Models
A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. Studying model organisms can be informative, but care must be taken when generalizing from one organism to another. In researching human disease, model organisms allow for better understanding the disease process without the added risk of harming an actual human. The species chosen will usually meet a determined taxonomic equivalency to humans, so as to react to disease or its treatment in a way that resemble ...
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Cell Lines
An immortalised cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods ''in vitro''. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms. Immortalised cell lines have also found uses in biotechnology. An immortalised cell line should not be confused with stem cells, which can also divide indefinitely, but form a normal part of the development of a multicellular organism. Relation to natural biology and pathology There are various immortal cell lines. Some of them are normal cell lines (e.g. derived from stem cells). Other immortalised cell lines are the ''in vitro'' equivalent of ...
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Plasmids
A plasmid is a small, extrachromosomal DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently. They are most commonly found as small circular, double-stranded DNA molecules in bacteria; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that benefit the survival of the organism and confer selective advantage such as antibiotic resistance. While chromosomes are large and contain all the essential genetic information for living under normal conditions, plasmids are usually very small and contain only additional genes that may be useful in certain situations or conditions. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms. In the laboratory, plasmids may be introduced into a cell via transformation. Synthetic plasmids are available for procurement over the intern ...
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Simple Machines Forum
Simple Machines Forum (SMF) software is an open-source web application that provides Internet forum and message board services. It is developed by Simple Machines. The name reflects the creator's initial goal of providing a website that could be operated by novice programmers and requires minimal server resources. Simple Machines won the ''forum-software.org'' best free forum software award in 2009. Organization Simple Machines Forum is an open-source discussion board software project of volunteers participating in various operating functions including development, customization, documentation, localization/translation, user support, and marketing. The project is owned by a non-profit organization, named ''Simple Machines''. Liroy van Hoewijk is president and CEO of the organization; Aleksi Kilpinen is the current project manager of SMF. "Sesquipedalian" is SMF's lead software developer. Simple Machines is organized and operates as a not-for-profit membership corporation organi ...
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Technology Demo
A technology demonstration (or tech demo), also known as demonstrator model, is a prototype, rough example or an otherwise incomplete version of a conceivable product or future system, put together as proof of concept with the primary purpose of showcasing the possible applications, feasibility, performance and method of an idea for a new technology. They can be used as demonstrations to the investors, partners, journalists or even to potential customers in order to convince them of the viability of the chosen approach, or to test them on ordinary users. Computers and gaming Technology demonstrations are often used in the computer industry, emerging as an important tool in response to short development cycles, in both software and hardware development. * Computer game developers use tech demos to rouse and maintain interest to titles still in development (because game engines are usually ready before the art is finished) and to ensure functionality by early testing. Short segments ...
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