Samuel Danishefsky
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Samuel Danishefsky
Samuel J. Danishefsky (born March 10, 1936) is an American chemist working as a professor at both Columbia University and the Memorial Sloan-Kettering Cancer Center in New York City. Birth and education Samuel J. Danishefsky was born in 1936 in the United States. He completed his B.S. from Yeshiva University in 1956. He earned his Ph.D. in chemistry from Harvard University in 1962 with Peter Yates (chemist), Peter Yates, which partially overlapped with a National Institutes of Health postdoctoral fellowship in the laboratory of Gilbert Stork at Columbia University. Academic career After completing his PhD, he became professor at the University of Pittsburgh, where he eventually attained the rank of University Professor and taught until 1979. From 1979 to 1993, he was a professor at Yale University, where he rose to the rank of Sterling Professor of Chemistry. By 1991 he was sharing his time with Memorial Sloan-Kettering Cancer Center as director of the Laboratory for Cancer Re ...
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United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territories, nine Minor Outlying Islands, and 326 Indian reservations. The United States is also in free association with three Pacific Island sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Republic of Palau. It is the world's third-largest country by both land and total area. It shares land borders with Canada to its north and with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the most populous country in the Americas and the third most populous in the world. The national capital of the United States is Washington, D.C. and its most populous city and principal financial center is New York City. Paleo-Americ ...
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Sterling Professor
Sterling Professor, the highest academic rank at Yale University, is awarded to a tenured faculty member considered the best in his or her field. It is akin to the rank of university professor at other universities. The appointment, made by the President of Yale University and confirmed by the Yale Corporation, can be granted to any Yale faculty member, and up to forty professors can hold the title at the same time. The position was established through a 1918 bequest from John William Sterling, and the first Sterling Professor was appointed in 1920. History The professorships are named for and funded by a $15-million bequest left by John W. Sterling, partner in the New York law firm Shearman & Sterling and an 1864 graduate of Yale College. In addition to financing the university’s largest construction projects throughout the 1920s, including the Sterling Memorial Library and flagship facilities for many of its professional schools, Sterling stipulated the bequest would allow ...
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The Scripps Research Institute
Scripps Research, previously known as The Scripps Research Institute (TSRI), is a nonprofit American medical research facility that focuses on research and education in the biomedical sciences. Headquartered in San Diego, California, the institute has over 170 laboratories employing 2,100 scientists, technicians, graduate students, and administrative and other staff, making it the largest private, non-profit biomedical research organization in the United States and among the largest in the world. The institute holds over 1,100 patents, has produced 11 FDA-approved therapeutics, and has generated over 50 spin-off companies. According to the 2017 Nature Innovation Index, Scripps Research is the #1 most influential research institution in the world. The Scripps Research graduate program is ranked 9th nationally in the biological sciences, 6th for organic chemistry, and 6th for biochemistry. In 2022, their Jupiter, FL campus became a part of the University of Florida. Jupiter-based ...
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The Franklin Institute Awards
The Franklin Institute Awards (or Benjamin Franklin Medal) is an American science and engineering award presented by the Franklin Institute, a science museum in Philadelphia. The Franklin Institute awards comprises the Benjamin Franklin Medals in seven areas of science and engineering, the Bower Awards and Prize for Achievement in Science, and the Bower Award for Business Leadership. Since 1824, the institute has recognized "world-changing scientists, engineers, inventors, and industrialists—all of whom reflect Benjamin Franklin’s spirit of curiosity, ingenuity, and innovation". Some of the noted past laureates include Nikola Tesla, Thomas Edison, Marie Curie, Max Planck, Albert Einstein, Stephen Hawking. Some of the 21st century laureates of the institute awards are Bill Gates, James P. Allison, Indra Nooyi, Jane Goodall, Elizabeth Blackburn, George Church, Robert S. Langer, and Alex Gorsky. Benjamin Franklin Medals In 1998, the Benjamin Franklin Medals were created b ...
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Benjamin Franklin Medal (Franklin Institute)
The Franklin Institute Awards (or Benjamin Franklin Medal) is an American science and engineering award presented by the Franklin Institute, a science museum in Philadelphia. The Franklin Institute awards comprises the Benjamin Franklin Medals in seven areas of science and engineering, the Bower Awards and Prize for Achievement in Science, and the Bower Award for Business Leadership. Since 1824, the institute has recognized "world-changing scientists, engineers, inventors, and industrialists—all of whom reflect Benjamin Franklin’s spirit of curiosity, ingenuity, and innovation". Some of the noted past laureates include Nikola Tesla, Thomas Edison, Marie Curie, Max Planck, Albert Einstein, Stephen Hawking. Some of the 21st century laureates of the institute awards are Bill Gates, James P. Allison, Indra Nooyi, Jane Goodall, Elizabeth Blackburn, George Church, Robert S. Langer, and Alex Gorsky. Benjamin Franklin Medals In 1998, the Benjamin Franklin Medals were created b ...
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Arthur C
Arthur is a common male given name of Brythonic origin. Its popularity derives from it being the name of the legendary hero King Arthur. The etymology is disputed. It may derive from the Celtic ''Artos'' meaning “Bear”. Another theory, more widely believed, is that the name is derived from the Roman clan '' Artorius'' who lived in Roman Britain for centuries. A common spelling variant used in many Slavic, Romance, and Germanic languages is Artur. In Spanish and Italian it is Arturo. Etymology The earliest datable attestation of the name Arthur is in the early 9th century Welsh-Latin text ''Historia Brittonum'', where it refers to a circa 5th to 6th-century Briton general who fought against the invading Saxons, and who later gave rise to the famous King Arthur of medieval legend and literature. A possible earlier mention of the same man is to be found in the epic Welsh poem ''Y Gododdin'' by Aneirin, which some scholars assign to the late 6th century, though this is still a ...
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Tetrahedron Prize
The Tetrahedron Prize for Creativity in Organic Chemistry or Bioorganic and Medicinal Chemistry is awarded annually by Elsevier, the publisher of Tetrahedron Publications. It was established in 1980 and named in honour of the founding co-chairmen of these publications, Professor Sir Robert Robinson and Professor Robert Burns Woodward. The prize consists of a gold medal, a certificate, and a monetary award of US $15,000. Prizewinners Winners of the prize are: See also * List of chemistry awards This list of chemistry awards is an index to articles about notable awards for chemistry. It includes awards by the Royal Society of Chemistry, the American Chemical Society, the Society of Chemical Industry and awards by other organizations. ... References {{reflist Awards established in 1981 British science and technology awards Chemistry awards ...
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American Chemical Society
The American Chemical Society (ACS) is a scientific society based in the United States that supports scientific inquiry in the field of chemistry. Founded in 1876 at New York University, the ACS currently has more than 155,000 members at all degree levels and in all fields of chemistry, chemical engineering, and related fields. It is one of the world's largest scientific societies by membership. The ACS is a 501(c) organization, 501(c)(3) non-profit organization and holds a congressional charter under Title 36 of the United States Code. Its headquarters are located in Washington, D.C., and it has a large concentration of staff in Columbus, Ohio. The ACS is a leading source of scientific information through its peer-reviewed scientific journals, national conferences, and the Chemical Abstracts Service. Its publications division produces over 60 Scientific journal, scholarly journals including the prestigious ''Journal of the American Chemical Society'', as well as the weekly tra ...
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Total Synthesis
Total synthesis is the complete chemical synthesis of a complex molecule, often a natural product, from simple, commercially-available precursors. It usually refers to a process not involving the aid of biological processes, which distinguishes it from semisynthesis. Syntheses may sometimes conclude at a precursor with further known synthetic pathways to a target molecule, in which case it is known as a formal synthesis. Total synthesis target molecules can be natural products, medicinally-important active ingredients, known intermediates, or molecules of theoretical interest. Total synthesis targets can also be organometallic or inorganic, though these are rarely encountered. Total synthesis projects often require a wide diversity of reactions and reagents, and subsequently requires broad chemical knowledge and training to be successful. Often, the aim is to discover a new route of synthesis for a target molecule for which there already exist known routes. Sometimes, however, no ...
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Taxol
Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer. This includes ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. It is administered by intravenous injection. There is also an albumin-bound formulation. Common side effects include hair loss, bone marrow suppression, numbness, allergic reactions, muscle pains, and diarrhea. Other serious side effects include heart problems, increased risk of infection, and lung inflammation. There are concerns that use during pregnancy may cause birth defects. Paclitaxel is in the taxane family of medications. It works by interference with the normal function of microtubules during cell division. Paclitaxel was first isolated in 1971 from the Pacific yew and approved for medical use in 1993. It is on the World Health Organization's List of Essential Medicines. It has been made from p ...
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