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SMIM20
Small integral membrane protein (SMIM) 20 is a protein that in humans is encoded by the SMIM20 gene. SMIM20 acts as a prohormone to the peptide hormone phoenixin which was discovered for the first time in 2013 in rodent sensory ganglia. In the study of the evolution of nervous systems#Neural_precursors, evolution of nervous systems, SMIM20 together with NUCB2 have been found to have deep Sequence homology, homology across all lineages that preceded creatures with central nervous systems, Bilateria, bilaterians, Cnidaria, cnidarians, Ctenophora, ctenophores, and Sponge, sponges as well as in choanoflagellates. References Further reading Genes Human proteins {{gene-4-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolution Of Nervous Systems
The evolution of nervous systems dates back to the first development of nervous systems in animals (or metazoans). Neurons developed as specialized electrical signaling cells in multicellular animals, adapting the mechanism of action potentials present in motile single-celled and colonial eukaryotes. Primitive systems, like those found in protists, use chemical signalling for movement and sensitivity; data suggests these were precursors to modern neural cell types and their synapses. When some animals started living a mobile lifestyle and eating larger food particles externally, they developed ciliated epithelia, contractile muscles and coordinating & sensitive neurons for it in their outer layer. Simple nerve nets seen in acoels (basal bilaterians) and cnidarians are thought to be the ancestral condition for the Planulozoa (bilaterians plus cnidarians and, perhaps, placozoans). A more complex nerve net with simple nerve cords is present in ancient animals called cteno ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
