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Sue Fletcher
Sue Fletcher is a professor and lecturer at the University of Western Australia and a Senior Principal Research Fellow at Murdoch University. She studies the field of molecular and cell biology and holds the position of chief scientific officer at PYC therapeutics. Currently her research is focused on inherited retinal disease, the central nervous system and neurodegeneration. Alongside Professor Steve Winton she developed novel treatments for Duchenne muscular dystrophy, including eteplirsen, which was the first of its kind to be approved by the FDA in 2016. In 2021 she was appointed an Officer of the Order of Australia for "distinguished service to medical research, to neurological science, and to the treatment and support of those with Muscular Dystrophy". Career and research Fletcher completed an undergraduate degree at the University of Zimbabwe. She then moved to Perth, where she completed a PhD at the University of Western Australia, with her thesis titled "The expression ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Western Australia
The University of Western Australia (UWA) is a public research university in the Australian state of Western Australia. The university's main campus is in Perth, the state capital, with a secondary campus in Albany, Western Australia, Albany and various other facilities elsewhere. UWA was established in 1911 by an act of the Parliament of Western Australia and began teaching students two years later. It is the sixth-oldest university in Australia and was Western Australia's only university until the establishment of Murdoch University in 1973. Because of its age and reputation, UWA is classed one of the "sandstone universities", an informal designation given to the oldest university in each state. The university also belongs to several more formal groupings, including the Group of Eight (Australian universities), Group of Eight and the Matariki Network of Universities. In recent years, UWA has generally been ranked either in the bottom half or just outside the University rankings ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Murdoch University
Murdoch University is a public university in Perth, Western Australia, with campuses also in Singapore and Dubai. It began operations as the state's second university on 25 July 1973, and accepted its first undergraduate students in 1975. Its name is taken from Sir Walter Murdoch (1874–1970), the Founding Professor of English and former Chancellor of the University of Western Australia. Murdoch is a verdant university and a member of the Innovative Research Universities. In 2018, Murdoch University was recognised as producing the most employable graduates of all Australian universities after 3 years of graduating from their courses. In 2019, the university ranked third in overall student satisfaction amongst all public universities in Western Australia. History In 1962, the Government of Western Australia earmarked an area of land in Bull Creek to be the site of a future, second, state university. Integral to the planning of the creation of Western Australia's second univ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a severe type of muscular dystrophy that primarily affects boys. Muscle weakness usually begins around the age of four, and worsens quickly. Muscle loss typically occurs first in the thighs and pelvis followed by the arms. This can result in trouble standing up. Most are unable to walk by the age of 12. Affected muscles may look larger due to increased fat content. Scoliosis is also common. Some may have intellectual disability. Females with a single copy of the defective gene may show mild symptoms. The disorder is X-linked recessive. About two thirds of cases are inherited from a person's mother, while one third of cases are due to a new mutation. It is caused by a mutation in the gene for the protein dystrophin. Dystrophin is important to maintain the muscle fiber's cell membrane. Genetic testing can often make the diagnosis at birth. Those affected also have a high level of creatine kinase in their blood. Although there is no know ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eteplirsen
Eteplirsen (brand name Exondys 51) is a medication to treat, but not cure, some types of Duchenne muscular dystrophy (DMD), caused by a specific mutation. Eteplirsen only targets specific mutations and can be used to treat about 14% of DMD cases. Eteplirsen is a form of antisense therapy. Eteplirsen was developed by Steve Wilton, Sue Fletcher and colleagues at the University of Western Australia and commercialized by Sarepta Therapeutics. After a controversial debate surrounding the drug's efficacy, during which two FDA review panel members resigned in protest, eteplirsen received accelerated approval from the US Food and Drug administration in late 2016. The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) refused to authorize the use of eteplirsen. Adverse effects The following adverse events were observed in at least 10% of people who received eteplirsen in trials: vomiting, contusion, excoriation, arthralgia, rash, catheter site pain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C), but the agency also enforces other laws, notably Section 361 of the Public Health Service Act, as well as associated regulations. Much of this regulatory-enforcement work is not d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Of Australia
The Order of Australia is an honour that recognises Australian citizens and other persons for outstanding achievement and service. It was established on 14 February 1975 by Elizabeth II, Queen of Australia, on the advice of the Australian Government. Before the establishment of the order, Australian citizens received British honours. The Monarch of Australia is sovereign head of the order, while the Governor-General of Australia is the principal companion/dame/knight (as relevant at the time) and chancellor of the order. The governor-general's official secretary, Paul Singer (appointed August 2018), is secretary of the order. Appointments are made by the governor-general on behalf of the Monarch of Australia, based on recommendations made by the Council of the Order of Australia. Recent knighthoods and damehoods were recommended to the governor-general by the Prime Minister of Australia. Levels of membership The order is divided into a general and a military division. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Zimbabwe
The University of Zimbabwe (UZ) is a public university in Harare, Zimbabwe. It opened in 1952 as the University College of Rhodesia and Nyasaland, and was initially affiliated with the University of London. It was later renamed the University of Rhodesia, and adopted its present name upon Zimbabwe's independence in 1980. UZ is the oldest and best ranked university in Zimbabwe. The university has eleven faculties and one college (with faculties of Agriculture, Arts, Commerce, Education, Engineering, Law, Science, Social Studies, Veterinary Sciences and the College of Health Sciences) offering a wide variety of degree programmes and many specialist research centres and institutes. The university is accredited through the National Council for Higher Education, under the Ministry of Higher and Tertiary Education. English is the language of instruction. Although once a very successful university, UZ has been facing challenges since 2008 and now the university is on a rebounding driv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Australian Academy Of Health And Medical Sciences
The Australian Academy of Health and Medical Sciences is an academy to promote health and medical sciences in Australia. It was established in June 2014. It cites "The Academy will serve the three purposes identified as of high priority in the 2013 Strategic Review of Health and Medical Research": * Mentoring the next generation of clinician researchers * Providing independent advice to government and others on issues relating to evidence-based medical practice and medical researchers * Providing a forum for discussion on progress on medical research with an emphasis on translation of research into practice Fellowship In 2014 the academy commenced awarding the honour of "Fellow of the Australian Academy of Health and Medical Sciences" to 50 medical scientists each year. Elected fellows include: * John Aitken elected 2015 * Warwick Anderson (born 1958) elected 2015 * Louise Baur elected 2014 * C. Glenn Begley elected 2015 * Samuel Berkovic (born 1953) elected 2015 * Jeffrey ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Officers Of The Order Of Australia
An officer is a person who has a position of authority in a hierarchical organization. The term derives from Old French ''oficier'' "officer, official" (early 14c., Modern French ''officier''), from Medieval Latin ''officiarius'' "an officer," from Latin ''officium'' "a service, a duty" the late Latin from ''officiarius'', meaning "official." Examples Ceremonial and other contexts *Officer, and/or Grand Officer, are both a grade, class, or rank of within certain chivalric orders and orders of merit, e.g. Legion of Honour (France), Order of the Holy Sepulchre (Holy See), Order of the British Empire ( UK), Order of Leopold (Belgium) *Great Officer of State *Merchant marine officer or licensed mariner *Officer of arms * Officer in The Salvation Army, and other state decorations Corporations * Bank officer *Corporate officer, a corporate title **Chief executive officer (CEO) **Chief financial officer (CFO) **Chief operating officer (COO) *Executive officer Education *Chief academic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fellows Of The Australian Academy Of Health And Medical Sciences
Fellows may refer to Fellow, in plural form. Fellows or Fellowes may also refer to: Places * Fellows, California, USA * Fellows, Wisconsin, ghost town, USA Other uses * Fellows Auctioneers, established in 1876. * Fellowes, Inc., manufacturer of workspace products *Fellows, a partner in the firm of English canal carriers, Fellows Morton & Clayton * Fellows (surname) See also *North Fellows Historic District The North Fellows Historic District is a historic district located in Ottumwa, Iowa, United States. The city experienced a housing boom after World War II. This north side neighborhood of single-family brick homes built between 1945 and 195 ..., listed on the National Register of Historic Places in Wapello County, Iowa * Justice Fellows (other) {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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