Snake Antivenom
Snake antivenom is a medication made up of antibodies used to treat snake bites by venomous snakes. It is a type of antivenom. It is a biological product that typically consists of venom neutralizing antibodies derived from a host animal, such as a horse or sheep. The host animal is hyperimmunized to one or more snake venoms, a process which creates an immunological response that produces large numbers of neutralizing antibodies against various components (toxins) of the venom. The antibodies are then collected from the host animal, and further processed into snake antivenom for the treatment of envenomation. It is on the World Health Organization's List of Essential Medicines. Production Antivenoms are typically produced using a donor animal, such as a horse or sheep. The donor animal is hyperimmunized with non-lethal doses of one or more venoms to produce a neutralizing antibody response. Then, at certain intervals, the blood from the donor animal is collected and neut ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Antibodies
An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that cause disease. Each individual antibody recognizes one or more specific antigens, and antigens of virtually any size and chemical composition can be recognized. Antigen literally means "antibody generator", as it is the presence of an antigen that drives the formation of an antigen-specific antibody. Each of the branching chains comprising the "Y" of an antibody contains a paratope that specifically binds to one particular epitope on an antigen, allowing the two molecules to bind together with precision. Using this mechanism, antibodies can effectively "tag" the antigen (or a microbe or an infected cell bearing such an antigen) for attack by cells of the immune system, or can neutralize it directly (for example, by blocking a part of a viru ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Venom
Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved ''venom apparatus'', such as fangs or a stinger, in a process called ''envenomation''. Venom is often distinguished from ''poison'', which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and ''toxungen'', which is actively transferred to the external surface of another animal via a physical delivery mechanism. Venom has evolved in terrestrial and marine environments and in a wide variety of animals: both predators and prey, and both vertebrates and invertebrates. Venoms kill through the action of at least four major classes of toxin, namely necrosis, necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; myotoxins, which damage muscles; and Hemotoxin, haemotoxins, which disrupt Thrombus, blood clotti ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sea Snake
Sea snakes, or coral reef snakes, are Elapidae, elapid snakes that inhabit Marine (ocean), marine environments for most or all of their lives. They belong to two subfamilies, Hydrophiinae and Sea krait, Laticaudinae. Hydrophiinae also includes Australasian terrestrial snakes, whereas Laticaudinae only includes the sea kraits (''Laticauda''), of which three species are found exclusively in freshwater. If these three freshwater species are excluded, there are 69 species of sea snakes divided among seven Genus, genera. Most sea snakes are venomous snake, venomous, except the genus ''Emydocephalus'', which feeds almost exclusively on fish eggs. Sea snakes are extensively adapted to a fully aquatic life and are unable to move on land, except for the sea kraits, which have limited land movement. They are found in warm coastal waters from the Indian Ocean to the Pacific and are closely related to venomous terrestrial snakes in Australia. All sea snakes have paddle-like tails and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Elapidae
Elapidae (, commonly known as elapids , from , variant of "sea-fish") is a family of snakes characterized by their permanently erect fangs at the front of the mouth. Most elapids are venomous, with the exception of the genus '' Emydocephalus''. Many members of this family exhibit a threat display of rearing upwards while spreading out a neck flap. Elapids are endemic to tropical and subtropical regions around the world, with terrestrial forms in Asia, Australia, Africa, and the Americas and marine forms in the Pacific and Indian Oceans. Members of the family have a wide range of sizes, from the white-lipped snake to the king cobra. Most species have neurotoxic venom that is channeled by their hollow fangs, and some may contain other toxic components in varying proportions. The family includes 55 genera with around 360 species and over 170 subspecies. Description Terrestrial elapids look similar to the Colubridae; almost all have long, slender bodies with smooth scales, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dispholidus Typus
The boomslang ( or ; ''Dispholidus typus'') is a highly venomous snake in the family Colubridae. The species is native to Sub-Saharan Africa. Etymology Its common name means "tree snake" in Dutch language, Dutch and Afrikaans – ''boom'' meaning "tree", and ''slang'' meaning "snake". In Afrikaans, the name is pronounced . Taxonomy The boomslang is a colubrid snake within the subfamily Colubrinae. It belongs to the genus ''Dispholidus'', which contains two other species, ''Dispholidus pembae, D. pembae'' and ''Dispholidus punctatus, D. punctatus''. The boomslang is thought to be closely related to members of the genus, genera ''Thelotornis'', ''Thrasops'', ''Rhamnophis'', and ''Xyelodontophis'', with which it forms the taxonomic tribe (biology), tribe Dispholidini. Close relationships can be shown in the cladogram below: Subspecies Two subspecies are recognised, including the nominotypical subspecies. * ''D. t. kivuensis'' * ''D. t. typus'' The Trinomen, trinomial auth ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Colubridae
Colubridae (, commonly known as colubrids , from , 'snake') is a family of snakes. With 249 genera, it is the largest snake family. The earliest fossil species of the family date back to the Late Eocene epoch, with earlier origins suspected. Colubrid snakes are found on every continent except Antarctica. Description Colubrids are a very diverse group of snakes. They can exhibit many different body styles, body sizes, colors, and patterns. They can also live in many different types of habitats including aquatic, terrestrial, semi-arboreal, arboreal, desert, mountainous forests, semi-fossorial, and brackish waters. A primarily shy and harmless group of snakes, the vast majority of colubrids are not venomous, nor do most colubrids produce venom that is medically significant to mammals. However, the bites of some can escalate quickly to emergency situations. Furthermore, within the Colubridae, the South African boomslang and twig snakes, as well as the Asian keelback snakes (' ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Atractaspididae
The Atractaspididae (atractaspidids) are a Family (biology), family of venomous snakes found in Africa and the Middle East, commonly called mole vipers, stiletto snakes, or burrowing asps. Currently, 12 genus, genera are recognized. Description This family includes many genera formerly classed in other families and subfamilies, on the basis of fang type. It includes fangless (aglypha, aglyphous), rear-fanged (opisthoglypha, opisthoglyphous), fixed-fanged (proteroglypha, proteroglyphous), and viper-like (solenoglypha, solenoglyphous) species. Early molecular and physiological data linking this subfamily to others were ambiguous and often contradictory, which means the Taxonomy (biology), taxonomy of this subfamily has been highly contentious. The nominate family, Atractaspididae, has itself been moved to and from other taxa, such as potentially forming a trichotomy with Elapidae and Colubridae, reinforcing the ambiguity of this subfamily. Geographic range This subfamily is found i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Arizona College Of Medicine
A university () is an institution of tertiary education and research which awards academic degrees in several academic disciplines. ''University'' is derived from the Latin phrase , which roughly means "community of teachers and scholars". Universities typically offer both undergraduate and postgraduate programs. The first universities in Europe were established by Catholic monks. The University of Bologna (), Italy, which was founded in 1088, is the first university in the sense of: *being a high degree-awarding institute. *using the word (which was coined at its foundation). *having independence from the ecclesiastic schools and issuing secular as well as non-secular degrees (with teaching conducted by both clergy and non-clergy): grammar, rhetoric, logic, theology, canon law and notarial law.Hunt Janin: "The university in medieval life, 1179–1499", McFarland, 2008, , p. 55f.de Ridder-Symoens, Hilde''A History of the University in Europe: Volume 1, Universities in the M ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Coralmyn
Coralmyn, also called Polyvalent Anti-coral Fabotherapic, is a polyclonal antivenom Antivenom, also known as antivenin, venom antiserum, and antivenom immunoglobulin, is a specific treatment for envenomation. It is composed of antibodies and used to treat certain venomous bites and stings. Antivenoms are recommended only if ... F(ab')2 used to treat venomous bites in mammals from the eastern coral snake and the Texas coral snake. It was manufactured in Mexico by the '' Instituto Bioclon'', and was only obtainable in the United States with an application of an USDA importer's permit and state license. Because of the relative rarity of such bites, the remaining United States reserve of this medicine has been restricted to human-only use and is set to expire in 2017. Treatment of small animals (dogs and cats) with this product following accidental bites had proven highly effective in preventing shock and death. References {{reflist Antitoxins ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Coral Snake
Coral snakes are a large group of elapid snakes that can be divided into two distinct groups, the Old World coral snakes and New World coral snakes. There are 27 species of Old World coral snakes, in three genera ('' Calliophis'', '' Hemibungarus'', and '' Sinomicrurus''), and 83 recognized species of New World coral snakes, in two genera ('' Micruroides'' and '' Micrurus''). Genetic studies have found that the most basal lineages have origins in Asia, suggesting that the group originated in the Old World. While new world species of both genera are venomous, their bites are seldom lethal; only two confirmed fatalities have been documented in the past 100 years from the genus ''Micrurus''. Meanwhile, snakes of the genus ''Micruroides'' have never caused a medically significant bite. North American coloration patterns Experts now recognize that certain coloration patterns and common mnemonics—such as the phrase “Red against yellow, deadly fellow; red against black, friendly J ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Bothrops Asper
The terciopelo (''Bothrops asper'') is a species of pit vipers, found from north-east Mexico to northern South America. At low to moderate elevations, its habitat ranges from northeastern Mexico to Colombian and Ecuadorian Andes, as well as Venezuela. With a mass of up to , and a maximal length of , the terciopelo is among the largest vipers. It is light to dark brown in color, often with yellowish, zig-zag patterning on either side of its body. Dubbed "the ultimate pit-viper" for its defensiveness, large size, fangs and potent venom yield, it has a fearsome reputation, responsible for the most Envenomation, envenomated snakebites within its range, largely due to its proximity to humans, livestock and pets. Nonetheless, like all venomous snakes, the terciopelo actively avoids contact with humans and larger animals, with bites generally only occurring when the snake is cornered, pursued, or threatened. No subspecies are currently recognized. Etymology The Genus, generic name, ''Bot ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |