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Sleep Latency
In sleep science, sleep onset latency (SOL) is the length of time that it takes to accomplish the transition from full wakefulness to sleep, normally to the lightest of the non-REM sleep stages. Sleep latency studies Pioneering Stanford University sleep researcher William C. Dement reports early development of the concept, and of the first test for it, the Multiple Sleep Latency Test (MSLT), in his book ''The Promise of Sleep''. Dement and colleagues including Mary Carskadon had been seeking an objective measure of daytime sleepiness to help assess the effects of sleep disorders. In the course of evaluating experimental results, they realized that the amount of time it took to fall asleep in bed was closely linked to the subjects' own self-evaluated level of sleepiness. "This may not seem like an earthshaking epiphany, but conceiving and developing an objective measure of sleepiness was perhaps one of the most important advances in sleep science," Dement and coauthor Christopher ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-REM Sleep
Non-rapid eye movement sleep (NREM), also known as quiescent sleep, is, collectively, sleep stages 1–3, previously known as stages 1–4. Rapid eye movement sleep (REM) is not included. There are distinct electroencephalographic and other characteristics seen in each stage. Unlike REM sleep, there is usually little or no eye movement during these stages. Dreaming occurs during both sleep states, and muscles are not paralyzed as in REM sleep. People who do not go through the sleeping stages properly get stuck in NREM sleep, and because muscles are not paralyzed a person may be able to sleepwalk. According to studies, the mental activity that takes place during NREM sleep is believed to be thought-like, whereas REM sleep includes hallucinatory and bizarre content. NREM sleep is characteristic of dreamer-initiated friendliness, compared to REM sleep where it's more aggressive, implying that NREM is in charge of simulating friendly interactions. The mental activity that occurs in NR ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William C
William is a male given name of Germanic origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the given name ''Wilhelm'' (cf. Proto-Germanic ᚹᛁᛚᛃᚨᚺᛖᛚᛗᚨᛉ, ''*Wiljahelmaz'' > German ''Wilhelm'' and Old Norse ᚢᛁᛚᛋᛅᚼᛅᛚᛘᛅᛋ, ''Vilhjálmr''). By regular sound changes, the native, inherited English form of th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mary Carskadon
Mary A. Carskadon is one of the most prominent American researchers in sleep. She is a Professor in the Department of Psychiatry and Human Behavior at the Warren Alpert Medical School of Brown University. She is also the Director of the Sleep and Chronobiology Research Lab at E.P. Bradley Hospital. She is considered to be an expert on sleep and circadian rhythms during childhood, adolescence and young adulthood. She researches issues related to daytime sleepiness. She has also contributed important research on school start times as it relates to sleep patterns and sleepiness in adolescence. Every summer, Dr. Carskadon offers a prestigious summer internship for highly motivated students interested in sleep research at the Bradley Sleep Lab. These students, known as Dement Fellows, after William C. Dement, work in the sleep lab for the entirety of the summer and learn under Dr. Carskadon. Career Carskadon studied psychology at Gettysburg College and graduated in 1969. She recei ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sleep Debt
Sleep debt or sleep deficit is the cumulative effect of not getting enough sleep. A large sleep debt may lead to mental or physical fatigue, and can adversely affect one's mood, energy and ability to think clearly. There are two kinds of sleep debt: result of partial sleep deprivation, and of total sleep deprivation. Partial sleep deprivation occurs when a person or a lab animal sleeps too little for several days or weeks. Total sleep deprivation, on the other hand, occurs when the subject is being kept awake for at least 24 hours. There is debate in the scientific community over the specifics of sleep debt (see ), and it is not considered to be a disorder. Physiological effects of sleep debt Chronic sleep debt has a substantial health impact on the human body, specifically on metabolic and endocrine functions. A study published in ''The Lancet'' investigated the physiological effects of sleep debt by assessing the sympathovagal balance (an indicator of the sympathetic nerv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nathaniel Kleitman
Nathaniel Kleitman (April 26, 1895 – August 13, 1999) was an American physiologist and sleep researcher who served as Professor Emeritus in Physiology at the University of Chicago. He is recognized as the father of modern sleep research, and is the author of the seminal 1939 book ''Sleep and Wakefulness''. Biography Early life Nathaniel Kleitman was born in Chișinău, also known as Kishinev, the capital of the province of Bessarabia (now Moldova), in 1895 to a Jewish family. He was deeply interested in consciousness and reasoned that he could get insight in consciousness by studying the unconsciousness of sleep. Pogroms drove him to Palestine, and in 1915 he emigrated to the United States as a result of World War I. At the age of twenty, he landed in New York City penniless; in 1923, at age twenty-eight, he had worked his way through City College of New York and earned a PhD from the University of Chicago's Department of Physiology. His thesis was "Studies on the physiolog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amylase
An amylase () is an enzyme that catalyses the hydrolysis of starch (Latin ') into sugars. Amylase is present in the saliva of humans and some other mammals, where it begins the chemical process of digestion. Foods that contain large amounts of starch but little sugar, such as rice and potatoes, may acquire a slightly sweet taste as they are chewed because amylase degrades some of their starch into sugar. The pancreas and salivary gland make amylase (alpha amylase) to hydrolyse dietary starch into disaccharides and trisaccharides which are converted by other enzymes to glucose to supply the body with energy. Plants and some bacteria also produce amylase. Specific amylase proteins are designated by different Greek letters. All amylases are glycoside hydrolases and act on α-1,4-glycosidic bonds. Classification α-Amylase The α-amylases () ( CAS 9014-71-5) (alternative names: 1,4-α-D-glucan glucanohydrolase; glycogenase) are calcium metalloenzymes. By acting at random loca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sleep Medicine
Sleep medicine is a medical specialty or subspecialty devoted to the diagnosis and therapy of sleep disturbances and sleep disorder, disorders. From the middle of the 20th century, research has provided increasing knowledge and answered many questions about sleep-wake functioning. The rapidly evolving field has become a recognized medical subspecialty in some countries. Dental sleep medicine also qualifies for board certification in some countries. Properly organized, minimum 12-month, postgraduate training programs are still being defined in the United States. In some countries, the sleep researchers and the physicians who treat patients may be the same people. The first sleep clinics in the United States were established in the 1970s by interested physicians and allied health professions, technicians; the study, diagnosis and treatment of obstructive sleep apnea were their first tasks. As late as 1999, virtually any American physician, with no specific training in sleep medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sleep Disorders
A sleep disorder, or somnipathy, is a medical disorder of an individual's sleep patterns. Some sleep disorders are severe enough to interfere with normal physical, mental, social and emotional functioning. Polysomnography and actigraphy are tests commonly ordered for diagnosing sleep disorders. Sleep disorders are broadly classified into dyssomnias, parasomnias, circadian rhythm sleep disorders involving the timing of sleep, and other disorders including ones caused by medical or psychological conditions. When a person struggles to fall asleep and/or stay asleep with no obvious cause, it is referred to as insomnia, the most common sleep disorder. Others include sleep apnea, narcolepsy and hypersomnia (excessive sleepiness at inappropriate times), sleeping sickness (disruption of sleep cycle due to infection), sleepwalking, and night terrors. Sleep disruptions can be caused by various issues, including teeth grinding ( bruxism) and night terrors. Management of sleep disturbances ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
