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Shope Papilloma
The Shope papilloma virus (SPV), also known as cottontail rabbit papilloma virus (CRPV) or ''Kappapapillomavirus 2'', is a papillomavirus which infects certain leporids, causing keratinous carcinomas resembling horns, typically on or near the animal's head. The carcinomas can metastasize or become large enough to interfere with the host's ability to eat, causing starvation. Richard E. Shope investigated the horns and discovered the virus in 1933, an important breakthrough in the study of oncoviruses. The virus was originally discovered in cottontail rabbits in the Midwestern U.S., but can also infect brush rabbits, black-tailed jackrabbits, snowshoe hares, and European rabbits. History In the 1930s, hunters in northwestern Iowa reported that the rabbits they shot had several "horn" protrusions on many parts of their bodies including their faces and necks. The virus is also a possible source of myths about the jackalope, a rabbit with the horns of an antelope, and related ...
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International Committee On Taxonomy Of Viruses
The International Committee on Taxonomy of Viruses (ICTV) authorizes and organizes the taxonomic classification of and the nomenclatures for viruses. The ICTV has developed a universal taxonomic scheme for viruses, and thus has the means to appropriately describe, name, and classify every virus that affects living organisms. The members of the International Committee on Taxonomy of Viruses are considered expert virologists. The ICTV was formed from and is governed by the Virology Division of the International Union of Microbiological Societies. Detailed work, such as delimiting the boundaries of species within a family, typically is performed by study groups of experts in the families. History The International Committee on Nomenclature of Viruses (ICNV) was established in 1966, at the International Congress for Microbiology in Moscow, to standardize the naming of viruses. The ICVN published its first report in 1971. For viruses infecting vertebrates, the first report included ...
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Antelope
The term antelope is used to refer to many species of even-toed ruminant that are indigenous to various regions in Africa and Eurasia. Antelope comprise a wastebasket taxon defined as any of numerous Old World grazing and browsing hoofed mammals belonging to the family Bovidae of the order Artiodactyla. A stricter definition, also known as the "true antelopes," includes only the genera ''Gazella'', ''Nanger'', ''Eudorcas'' and ''Antilope''. One North American species, the pronghorn, is colloquially referred to as the "American antelope," but it belongs to a different family from the African and Eurasian antelopes. A group of antelope is called a herd. Unlike deer antlers, which are shed and grown annually, antelope horns grow continuously. Etymology The English word "antelope" first appeared in 1417 and is derived from the Old French ''antelop'', itself derived from Medieval Latin ''ant(h)alopus'', which in turn comes from the Byzantine Greek word ἀνθόλοψ, ''anthó ...
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Viral Diseases
Viral means "relating to viruses" (small infectious agents). Viral may also refer to: Viral behavior, or virality Memetic behavior likened that of a virus, for example: * Viral marketing, the use of existing social networks to spread a marketing message * Viral phenomenon, relating to contagion theory or the "virality" of network culture, such as a meme * Viral video, a video that quickly attains a high popularity Titled works * ''Viral'' (2016 American film), a 2016 American science fiction horror drama * ''Viral'' (2016 Hindi film), an Indian Bollywood film based on social media * ''Viral'' (web series), a 2014 Brazilian comedy web series * '' V/H/S: Viral'', an American anthology horror film * '' Viral: The Search for the Origin of COVID-19'', a book by Alina Chand and Matt Ridley See also * ''Virals'', a novel series by Kathy Reichs * Virulence Virulence is a pathogen's or microorganism's ability to cause damage to a host. In most, especially in animal system ...
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Leporid Diseases
Leporidae is the family of rabbits and hares, containing over 60 species of extant mammals in all. The Latin word ''Leporidae'' means "those that resemble ''lepus''" (hare). Together with the pikas, the Leporidae constitute the mammalian order Lagomorpha. Leporidae differ from pikas in that they have short, furry tails and elongated ears and hind legs. The common name "rabbit" usually applies to all genera in the family except ''Lepus'', while members of ''Lepus'' (almost half the species) usually are called hares. Like most common names, however, the distinction does not match current taxonomy completely; jackrabbits are members of ''Lepus'', and members of the genera ''Pronolagus'' and ''Caprolagus'' sometimes are called hares. Various countries across all continents except Antarctica and Australia have indigenous species of Leporidae. Furthermore, rabbits, most significantly the European rabbit, ''Oryctolagus cuniculus'', also have been introduced to most of Oceania and to ma ...
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Oncovirus
An oncovirus or oncogenic virus is a virus that can cause cancer. This term originated from studies of acutely transforming retroviruses in the 1950–60s, when the term "oncornaviruses" was used to denote their RNA virus origin. With the letters "RNA" removed, it now refers to any virus with a DNA or RNA genome causing cancer and is synonymous with "tumor virus" or "cancer virus". The vast majority of human and animal viruses do not cause cancer, probably because of longstanding co-evolution between the virus and its host. Oncoviruses have been important not only in epidemiology, but also in investigations of cell cycle control mechanisms such as the retinoblastoma protein. The World Health Organization's International Agency for Research on Cancer estimated that in 2002, infection caused 17.8% of human cancers, with 11.9% caused by one of seven viruses. A 2020 study of 2,658 samples from 38 different types of cancer found that 16% were associated with a virus. These cancers m ...
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Squamous Cell Carcinoma
Squamous-cell carcinomas (SCCs), also known as epidermoid carcinomas, comprise a number of different types of cancer that begin in squamous cells. These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts. Common types include: * Squamous-cell skin cancer: A type of skin cancer * Squamous-cell carcinoma of the lung: A type of lung cancer * Squamous-cell thyroid carcinoma: A type of thyroid cancer * Esophageal squamous-cell carcinoma: A type of esophageal cancer * Squamous-cell carcinoma of the vagina: A type of vaginal cancer Despite sharing the name "squamous-cell carcinoma", the SCCs of different body sites can show differences in their presented symptoms, natural history, prognosis, and response to treatment. By body location Human papillomavirus infection has been associated with SCCs of the oropharynx, lung, fingers, and anogenital region. Head and neck cancer About 90% of cases ...
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Open Reading Frame
In molecular biology, open reading frames (ORFs) are defined as spans of DNA sequence between the start and stop codons. Usually, this is considered within a studied region of a prokaryotic DNA sequence, where only one of the six possible reading frames will be "open" (the "reading", however, refers to the RNA produced by transcription of the DNA and its subsequent interaction with the ribosome in translation). Such an ORF may contain a start codon (usually AUG in terms of RNA) and by definition cannot extend beyond a stop codon (usually UAA, UAG or UGA in RNA). That start codon (not necessarily the first) indicates where translation may start. The transcription termination site is located after the ORF, beyond the translation stop codon. If transcription were to cease before the stop codon, an incomplete protein would be made during translation. In eukaryotic genes with multiple exons, introns are removed and exons are then joined together after transcription to yield the final ...
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HPV Vaccine
Human papillomavirus (HPV) vaccines are vaccines that prevent infection by certain types of human papillomavirus (HPV). Available HPV vaccines protect against either two, four, or nine types of HPV. All HPV vaccines protect against at least HPV types 16 and 18, which cause the greatest risk of cervical cancer. It is estimated that HPV vaccines may prevent 70% of cervical cancer, 80% of anal cancer, 60% of vaginal cancer, 40% of vulvar cancer, and show more than 90% efficacy in preventing HPV-positive oropharyngeal cancers. They additionally prevent some genital warts, with the quadrivalent and nonavalent vaccines that protect against HPV types HPV-6 and HPV-11 providing greater protection. The World Health Organization (WHO) recommends HPV vaccines as part of routine vaccinations in all countries, along with other prevention measures. The vaccines require two or three doses depending on a person's age and immune status. Vaccinating girls around the ages of nine to thirteen i ...
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Human Papillomavirus
Human papillomavirus infection (HPV infection) is caused by a DNA virus from the ''Papillomaviridae'' family. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. In some cases, an HPV infection persists and results in either warts or precancerous lesions. These lesions, depending on the site affected, increase the risk of cancer of the cervix, vulva, vagina, penis, anus, mouth, tonsils, or throat. Nearly all cervical cancer is due to HPV and two strains – HPV16 and HPV18 – account for 70% of cases. HPV16 is responsible for almost 90% of HPV-positive oropharyngeal cancers. Between 60% and 90% of the other cancers listed above are also linked to HPV. HPV6 and HPV11 are common causes of genital warts and laryngeal papillomatosis. An HPV infection is caused by ''human papillomavirus'', a DNA virus from the papillomavirus family. Over 170 types have been described. An individual can become infected with more than one type of HPV, and the dis ...
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DNA Sequencing
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Knowledge of DNA sequences has become indispensable for basic biological research, DNA Genographic Projects and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers, characterize antibody repertoire, and can be used to guide patient treatment. Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged. The rapid speed of sequencing attained with modern D ...
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Inoculate
Inoculation is the act of implanting a pathogen or other microorganism. It may refer to methods of artificially inducing immunity against various infectious diseases, or it may be used to describe the spreading of disease, as in "self-inoculation," the spreading of disease from one part of the body to another, or even to the spreading of bacteria in a Petri dish for culturing purposes. The terms "inoculation", "vaccination", and "immunization" are often used synonymously, but there are some important differences among them. Inoculation is the act of implanting a disease inside a person or animal, vaccination is the act of implanting or giving someone a vaccine specifically, and immunization is what happens to the immune system as a result. Terminology Until the early 1800s inoculation referred only to variolation (from the Latin word ''variola'' = smallpox), the predecessor to the smallpox vaccine. The smallpox vaccine, introduced by Edward Jenner in 1796, was called cowpox inoc ...
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Tableau Encyclopédique Et Méthodique
Tableau (French for 'little table' literally, also used to mean 'picture'; tableaux or, rarely, tableaus) may refer to: Arts * ''Tableau'', a series of four paintings by Piet Mondrian titled ''Tableau I'' through to ''Tableau IV'' * ''Tableau vivant'', a motionless performance evoking a painting or sculpture; or a painting or photograph evoking such a theatrical scene * Scene (drama), in opera, ballet, and some other dramatic forms Games * Tableau (card game), a specific patience card game * Tableau (cards), the layout in patience and fishing card games * Tableau (dominoes), the layout in dominoes Other * Tableau, another term for a table of data, particularly: ** Cryptographic tableau, or tabula recta, used in manual cipher systems ** Division tableau, a table used to do long division * Method of analytic tableaux (also semantic tableau or truth tree), a technique of automated theorem proving in logic * Tableau Software, a company providing tools for data visualization and bus ...
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