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Senna Reticulata
''Senna reticulata'', the ''mangerioba grande'' or ''maria mole'' in Portuguese, is a pioneer tree species found on highly fertile floodplains in South America. It has some medicinal uses, but is regarded by farmers as a noxious weed, named ''matapasto'' (meadow killer) due to its ability to grow fast and outshade neighbouring plants. Uses It is used in the local folk medicine for liver problems and rheumatism. 1,3,8-Trihydroxyanthraquinone is an organic compound found in alcoholic extracts of the wood of the plant. The extract also contains, among other products chrysophanol (1,8-dihydroxy-3-methylanthraquinone), physcion (1,8-dihydroxy-3-methyl-6-methoxyanthraquinone), aloe-emodin (3-carbinol-1,8-dihydroxyanthraquinone), lunatin (3-methoxy-1,6,8-trihydroxyanthraquinone), emodin (6-methyl-1,3,8-trihydroxyanthraquinone), and chrysophanol-10,10'-bianthrone.Santos Rogério Nunes dos, Silva Maria Goretti de Vasconcelos and Braz Fihlo Raimundo (2008). ''Constituintes químicos do ...
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Carl Ludwig Willdenow
Carl Ludwig Willdenow (22 August 1765 – 10 July 1812) was a German botanist, pharmacist, and plant taxonomist. He is considered one of the founders of phytogeography, the study of the geographic distribution of plants. Willdenow was also a mentor of Alexander von Humboldt, one of the earliest and best known phytogeographers. He also influenced Christian Konrad Sprengel, who pioneered the study of plant pollination and floral biology. Biography Willdenow was born in Berlin and studied medicine and botany at the University of Halle. After studying pharmaceutics at Wieglieb College, Langensalza and in medicine at Halle, he returned to Berlin to work at his father's pharmacy located in the Unter den Linden. His early interest in botany was kindled by his uncle J. G. Gleditsch and he started a herbarium collection in his teenage years. In 1794 he became a member of the Berlin Academy of Sciences. He was a director of the Botanical garden of Berlin from 1801 until his death. ...
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Aloe-emodin
Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action. Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kind of radiation. Aloe emodin is found in the gel, sap or leaves of aloe vera, the socotrine aloe, Barbados aloe, and Zanzibar aloes, the bark of ''Frangula'' ('' Rhamnus frangula'') and cascara sagrada ('' Rhamnus purshiana''), the leaves of Senna (''Cassia angustifolia ''Senna alexandrina'' (Alexandrian senna, in Arabic عشرج or عشرق or سنامكي and see below) is an ornamental plant in the genus '' Senna''. It is used in herbalism. It grows natively in upper Egypt, especially in the Nubian region, a ...''), and the rhizome of rhubarb ('' Rheum rhaponticum''). Aloe-emodin has not been found in Natal aloes. References See also * Emodin {{Anthraqu ...
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Rhein (molecule)
Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb. Like all such substances, rhein is a cathartic. Rhein is commonly found as a glycoside such as rhein-8-glucoside or glucorhein. Rhein was first isolated in 1895. It is found in rhubarb species like ''Rheum undulatum'' and ''Rheum palmatum'' as well as in ''Cassia reticulata''. Originally the rhubarb plant which contains rhein was used as a laxative. It was believed that rhein along with other anthraquinone glycosides imparted this activity. Rhein has been reevaluated as an antibacterial agent against ''Staphylococcus aureus'' in 2008. Synergy or partial synergy has been demonstrated between rhein and the antibiotics oxacillin and ampicillin. Rhein has been shown to inhibit the fat mass and obesity-associated protein, an enzyme responsible for removing the methylation from N6-methyladenosine in nucleic acids. The pharmacokinetics of rhein have not been intensively studied in humans ...
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Xanthonoid
A xanthonoid is a chemical natural phenolic compound formed from the xanthone backbone. Many members of the Clusiaceae contain xanthonoids. Xanthonoid biosynthesis in cell cultures of ''Hypericum androsaemum'' involves the presence of a benzophenone synthase condensing a molecule of benzoyl-CoA with three malonyl-CoA yielding to 2,4,6-trihydroxybenzophenone. This intermediate is subsequently converted by a benzophenone 3′-hydroxylase, a cytochrome P450 monooxygenase, leading to the formation of 2,3′,4,6-tetrahydroxybenzophenone. Some examples are tomentonone, zeyloxanthonone and calozeyloxanthone isolated from the bark of ''Calophyllum tomentosum'', apetalinone A, B, C and D from '' Calophyllum apetalum'', gaudichaudione A, B, C, D, E, F, G, H, gaudichaudiic acid A, B, C, D, E, morellic acid and forbesione from '' Garcinia gaudichaudii'', methylswertianin and bellidifolin from '' Swertia punicea'' or psorospermin obtained from '' Psorospermum febrifu ...
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Emodin
Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is a chemical compound, of the anthraquinone family, that can be isolated from rhubarb, buckthorn, and Japanese knotweed (''Reynoutria japonica'' syn. ''Polygonum cuspidatum''). Emodin is particularly abundant in the roots of the Chinese rhubarb (Rheum palmatum), knotweed and knotgrass (Polygonum cuspidatum and multiflorum) as well as Hawaii ‘au‘auko‘i cassia seeds or coffee weed (Semen cassia). It is specifically isolated from Rheum palmatum L. It is also produced by many species of fungi, including members of the genera ''Aspergillus'', ''Pyrenochaeta'', and ''Pestalotiopsis'', inter alia. The common name is derived from ''Rheum emodi'', a taxonomic synonym of ''Rheum australe'', (Himalayan rhubarb) and synonyms include emodol, frangula emodin, rheum emodin, 3-methyl-1,6,8-trihydroxyanthraquinone, Schüttgelb (Schuttgelb), and Persian Berry Lake. Pharmacology Emodin is an active component of several plants used in Traditiona ...
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Lunatin
Lunatin (3-methoxy-1,6,8-trihydroxyanthraquinone) is a derivative of anthraquinone. It is produced by the ''Senna reticulata'' tree and can be extracted by soaking the bark in alcohol. Lunatin is also produced by the fungus ''Curvularia lunata ''Cochliobolus lunatus'' is a fungal plant pathogen that can cause disease in humans and other animals. The anamorph of this fungus is known as ''Curvularia lunata'', while ''Cochliobolus lunatus'' denotes the teleomorph or sexual state. They ar ...'' which inhabits a marine sponge. Lunatin is an antibacterial substance. References {{Reflist Anthraquinones ...
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Physcion
Parietin is the predominant cortical pigment of lichens in the genus ''Caloplaca'', a secondary product of the lichen ''Xanthoria parietina'', and a pigment found in the roots of Curled Dock (''Rumex crispus''). It has an orangy-yellow color and absorbs blue light. It is also known as physcion. It has also been shown to protect lichens against UV-B light, at high altitudes in Alpine regions. The UV-B light stimulates production of parietin and the parietin protects the lichens from damage. Lichens in arctic regions such as Svarlbard retain this capability though they do not encounter damaging levels of UV-B, a capability that could help protect the lichens in case of Ozone layer thinning. It has also shown anti-fungal activity against barley powdery mildew and cucumber powdery mildew, more efficiently in the latter case than treatments with fenarimol and polyoxin B. It reacts with KOH to form a deep, reddish-magenta compound. Effect on human cancer cells Also found in rhub ...
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Howard Samuel Irwin
Howard Samuel Irwin Jr. (March 28, 1928 – January 23, 2019) was an American botanist and taxonomist who specialized in the genus '' Cassia'' and worked as an administrator at the New York Botanical Garden, Long Island University, and the Brooklyn Botanic Garden. Early life and education Irwin was born in Louisville, Kentucky, in 1928. He began his education at Mount Hermon School in Massachusetts, after which point he entered Hofstra College to pursue a career in music. He then transferred to the College of Puget Sound where he earned an undergraduate degree in biology with minors in music and history in 1950, and a subsequent degree in education. Irwin was then a Fulbright teacher of botany and zoology at Queen's College in British Guiana from 1952 until 1956. During that time he was a corespondent for ''Time'' magazine. In 1956 he began work on his PhD in taxonomic botany at the University of Texas, earning his degree in 1960. The New York Botanical Garden Irwin first bega ...
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Chrysophanol
Chrysophanol, also known as chrysophanic acid, is a fungal isolate and a natural anthraquinone. It is a C-3 methyl substituted chrysazin of the trihydroxyanthraquinone family. Chrysophanol (other names; 1,8-dihydroxy-3-methyl-anthraquinone and chrysophanic acid) was found commonly within Chinese medicine and is a naturally occurring anthraquinone. Studies have been conducted on the benefits of chrysophanol and have found that it can aid in preventing cancer, diabetes, asthma, osteoporosis, retinal degeneration, Alzheimer’s disease, osteoarthritis, and atherosclerosis. Its most common effects are of chemotherapeutic and neuroprotective properties. History Chrysophanol was first noted from ''Rheum rhabarbarum'' which is a plant belonging to the Polygonaceae family. It has since been discovered to be present in various families such as Liliaceae, Meliaceae, Asphodelaceae and Fabaceae among more. As of 2019, it has been observed in 65 species from 14 genera, not just in plants bu ...
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1,3,8-Trihydroxyanthraquinone
1,3,8-Trihydroxyanthraquinone is an organic compound. It is one of many trihydroxyanthraquinone isomers, formally derived from anthraquinone by replacement of three hydrogen atoms by hydroxyl (OH) groups. The compound occurs in some microorganisms and in ethanol, alcoholic extracts of the wood of the South American plant ''Senna reticulata'' (''mangerioba grande'' or ''maria mole'' in Portuguese language, Portuguese), used in the local folk medicine for liver problems and rheumatism. The extract also contained, among other products chrysophanol (1,8-dihydroxy-3-methylanthraquinone), physcion (1,8-dihydroxy-3-methyl-6-methoxyanthraquinone), aloe-emodin (3-carbinol-1,8-dihydroxyanthraquinone), lunatin (3-methoxy-1,6,8-trihydroxyanthraquinone), emodin (6-methyl-1,3,8-trihydroxyanthraquinone), and chrysophanol-10,10'-bianthrone. SANTOS, Rogério Nunes dos; SILVA, Maria Goretti de Vasconcelos, and BRAZ FILHO, Raimundo (2008). ''Constituintes químicos do caule de Senna reticulata Wi ...
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