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Schüffner's Dots
Schüffner's dots refers to a hematological finding that is associated with malaria, exclusively found in infections caused by ''Plasmodium ovale'' or ''Plasmodium vivax''. ''Plasmodium vivax'' induces morphologic alterations in infected host erythrocytes Red blood cells (RBCs), also referred to as red cells, red blood corpuscles (in humans or other animals not having nucleus in red blood cells), haematids, erythroid cells or erythrocytes (from Greek ''erythros'' for "red" and ''kytos'' for "holl ... that are visible by light microscopy in Romanowsky-stained blood smears as multiple brick-red dots. These morphologic changes, referred to as Schüffner's dots, are important in the identification of this species of malarial parasite and have been associated by electron microscopy with caveolavesicle complexes along the erythrocyte plasmalemma. They are named for Wilhelm Schüffner, who described them in 1904. References External links * http://pathmicro.med.sc.edu/parasito ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microphotograph Of Plasmodium Ovale Microgametocyte In Giemsa-stained Thin Blood Film, With Schüffner's Dots And Hemozoin Pigment
Microphotographs are photographs shrunk to microscopic scale.Focal encyclopedia of photography By Michael R. Peres Focal Press, 2007 , 846 pages Microphotography is the art of making such images. Applications of microphotography include such as in the , where they are known as |
P Ovale Troph3
P, or p, is the sixteenth letter (alphabet), letter of the Latin alphabet, used in the English alphabet, modern English alphabet, the alphabets of other western European languages and others worldwide. Its name in English is English alphabet#Letter names, ''pee'' (pronounced ), plural ''pees''. History The Semitic languages, Semitic Pê (mouth), as well as the Greek language, Greek Π or π (Pi (letter), Pi), and the Etruscan language, Etruscan and Latin letters that developed from the former alphabet, all symbolized , a voiceless bilabial plosive. Use in writing systems In English orthography and most other European languages, represents the sound . A common Digraph (orthography), digraph in English is , which represents the sound , and can be used to transliterate ''phi'' in loanwords from Greek language, Greek. In German, the digraph is common, representing a labial affricate . Most English words beginning with are of foreign origin, primarily French, Latin and Gree ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the ''Plasmodium'' group. It is spread exclusively through bites of infected ''Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spread by h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmodium Ovale
''Plasmodium ovale'' is a species of parasitic protozoon that causes tertian malaria in humans. It is one of several species of ''Plasmodium'' parasites that infect humans, including ''Plasmodium falciparum'' and ''Plasmodium vivax'' which are responsible for most cases of malaria in the world. ''P. ovale'' is rare compared to these two parasites, and substantially less dangerous than ''P. falciparum''. ''P. ovale'' has recently been shown by genetic methods to consist of what is considered to be two species (despite having been given subspecies names), namely '' P. ovale curtisi'' and '' P. ovale wallikeri''. History This species was first described in 1914 by Stephens in a blood sample taken in the autumn of 1913 from a patient in the sanitarium of Pachmari in central India and sent by Major W. H. Kenrick to Stephens (who was working in Liverpool). Epidemiology ''P. ovale'' is primarily concentrated in sub-Saharan Africa and islands in the western Pacific. However ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmodium Vivax
''Plasmodium vivax'' is a protozoal parasite and a human pathogen. This parasite is the most frequent and widely distributed cause of recurring malaria. Although it is less virulent than ''Plasmodium falciparum'', the deadliest of the five human malaria parasites, ''P. vivax'' malaria infections can lead to severe disease and death, often due to splenomegaly (a pathologically enlarged spleen). ''P. vivax'' is carried by the female ''Anopheles'' mosquito; the males do not bite. Health Epidemiology ''Plasmodium vivax'' is found mainly in Asia, Latin America, and in some parts of Africa. ''P. vivax'' is believed to have originated in Asia, but recent studies have shown that wild chimpanzees and gorillas throughout central Africa are endemically infected with parasites that are closely related to human ''P. vivax.'' These findings indicate that human P. vivax is of African origin. ''Plasmodium vivax'' accounts for 65% of malaria cases in Asia and South America. Unlike ''Pla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Erythrocytes
Red blood cells (RBCs), also referred to as red cells, red blood corpuscles (in humans or other animals not having nucleus in red blood cells), haematids, erythroid cells or erythrocytes (from Greek ''erythros'' for "red" and ''kytos'' for "hollow vessel", with ''-cyte'' translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system. RBCs take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillaries. The cytoplasm of a red blood cell is rich in hemoglobin, an iron-containing biomolecule that can bind oxygen and is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately 270 million hemoglobin molecules. The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiologi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Light Microscopy
Microscopy is the technical field of using microscopes to view objects and areas of objects that cannot be seen with the naked eye (objects that are not within the resolution range of the normal eye). There are three well-known branches of microscopy: optical microscope, optical, electron microscope, electron, and scanning probe microscopy, along with the emerging field of X-ray microscopy. Optical microscopy and electron microscopy involve the diffraction, reflection (physics), reflection, or refraction of electromagnetic radiation/electron beams interacting with the Laboratory specimen, specimen, and the collection of the scattered radiation or another signal in order to create an image. This process may be carried out by wide-field irradiation of the sample (for example standard light microscopy and transmission electron microscope, transmission electron microscopy) or by scanning a fine beam over the sample (for example confocal laser scanning microscopy and scanning electro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Romanowsky Stain
Romanowsky staining, also known as Romanowsky–Giemsa staining, is a prototypical staining technique that was the forerunner of several distinct but similar stains widely used in hematology (the study of blood) and cytopathology (the study of diseased cells). Romanowsky-type stains are used to differentiate cells for microscopic examination in pathological specimens, especially blood and bone marrow films, and to detect parasites such as malaria within the blood. Stains that are related to or derived from the Romanowsky-type stains include Giemsa, Jenner, Wright, Field, May–Grünwald and Leishman stains. The staining technique is named after the Russian physician Dmitri Leonidovich Romanowsky (1861–1921), who was one of the first to recognize its potential for use as a blood stain. Mechanism The value of Romanowsky staining lies in its ability to produce a wide range of hues, allowing cellular components to be easily differentiated. This phenomenon is referred to as the '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Microscopy
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a higher resolving power than light microscopes and can reveal the structure of smaller objects. A scanning transmission electron microscope has achieved better than 50 pm resolution in annular dark-field imaging mode and magnifications of up to about 10,000,000× whereas most light microscopes are limited by diffraction to about 200 nm resolution and useful magnifications below 2000×. Electron microscopes use shaped magnetic fields to form electron optical lens systems that are analogous to the glass lenses of an optical light microscope. Electron microscopes are used to investigate the ultrastructure of a wide range of biological and inorganic specimens including microorganisms, cells, large molecules, biopsy samples, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilhelm Schüffner
Wilhelm August Paul Schüffner (2 January 1867, Ovenstädt – 24 December 1949, Hilversum) was a German pathologist and epidemiologist who worked mainly in the Dutch East India colonies and specialized in the study of malaria. Schüffner received an MD from Leipzig and was made honorary MD by Amsterdam University in 1912. He identified the rodent reservoir of Leptospirosis. He was a medical officer from 1897 in the Semembah Tobacco estate in eastern Sumatra and until 1923 he worked in the Dutch colonies in Java and Indonesia studying malaria. He worked on the healthcare of plantation workers in Senembah Maatschappij, Deli, North Sumatra. He demonstrated malaria control through management of hygiene. He recorded the characteristic red stippling found in red blood cells of patients infected by tertian malaria (''Plasmodium vivax'') which are now known as Schüffner's dots. From 1916 he was a public health advisor to the colonial government of the Dutch East India Company. He was e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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