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Schmidt Sting Pain Index
The Schmidt sting pain index is a pain scale rating the relative pain caused by different hymenopteran stings. It is mainly the work of Justin O. Schmidt (born 1947), an entomologist at the Carl Hayden Bee Research Center in Arizona, United States. Schmidt has published a number of papers on the subject, and claims to have been stung by the majority of stinging Hymenoptera. His original paper in 1983 was a way to systematize and compare the hemolytic properties of insect venoms. A table contained in the paper included a column that rated sting pain, starting from 0 for stings that are completely ineffective against humans, progressing through 2, a familiar pain such as that caused by a common bee or wasp sting, and finishing at 4 for the most painful stings; in the original paper, only the bullet ant, '' Paraponera clavata'', was given a rating of 4. Later revised versions of the index added '' Synoeca septentrionalis'', along with tarantula hawks as the only species to share ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Synoeca Surinama
''Synoeca surinama'' is a Neotropical swarm-founding wasp of the tribe Epiponini. It is known for its metallic blue and black appearance and painful sting. ''S. surinama'' builds nests on tree trunks and can be found in tropical climates of South America. When preparing to swarm, there are a number of pre-swarming behaviors that members of ''S. surinama'' colonies partake in, such as buzzing runs and occasional brood cannibalism. In ''S. surinama'', social environmental conditions determine the caste ranks of individuals in the developing brood. Unlike less primitive Hymenoptera species, ''S. surinama'' display little morphological variation between egg laying queens and workers. ''S. surinama'' wasps visit flowering plants and are considered pollinators. When these wasps sting, the stinger is left in the victim and the wasp ultimately dies. Taxonomy and phylogenetics The genus ''Synoeca'' is small, monophyletic, and is made up of the five species ''Synoeca chalibea, S. chalibea'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Outside (magazine)
''Outside'' is an American company and magazine focused on the outdoors. The first issue of ''Outside'' was published in September 1977. History Outside founders were Jann Wenner (the first editor in chief), William Randolph Hearst III (its first managing editor), and Jack Ford (an assistant to founding publisher Donald Welsh and a son of former U.S. President Gerald Ford). Wenner sold ''Outside'' to Lawrence J. Burke two years later. Burke merged it into his magazine ''Mariah'' (founded in 1976) and after a period of using the name ''Mariah/Outside'' kept the ''Outside'' name for the merged magazine. Christopher Keyes is the current editor. Outside, formerly Pocket Outdoor Media, acquired Outside Integrated Media in February 2021. Outside brands include Outside Magazine, Outside Business Journal, Outside Integrated Media, Outside TV, Gaia GPS, fastestknowntime.com, athleteReg, Peloton Magazine, Yoga Journal, SKI, Backpacker, VeloNews, Climbing, Rock & Ice, Gym Climber, Trai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotoxin
Neurotoxins are toxins that are destructive to nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insultsSpencer 2000 that can adversely affect function in both developing and mature nervous tissue.Olney 2002 The term can also be used to classify endogenous compounds, which, when abnormally contacted, can prove neurologically toxic. Though neurotoxins are often neurologically destructive, their ability to specifically target neural components is important in the study of nervous systems. Common examples of neurotoxins include lead, ethanol (drinking alcohol), glutamate,Choi 1987 nitric oxide, botulinum toxin (e.g. Botox), tetanus toxin,Simpson 1986 and tetrodotoxin. Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive concentrations. Neurotoxins inhibit neuron control over ion concentrations across the cell membrane, or commu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
White Blood Cell
White blood cells, also called leukocytes or leucocytes, are the cells of the immune system that are involved in protecting the body against both infectious disease and foreign invaders. All white blood cells are produced and derived from multipotent cells in the bone marrow known as hematopoietic stem cells. Leukocytes are found throughout the body, including the blood and lymphatic system. All white blood cells have nuclei, which distinguishes them from the other blood cells, the anucleated red blood cells (RBCs) and platelets. The different white blood cells are usually classified by cell lineage (myeloid cells or lymphoid cells). White blood cells are part of the body's immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosinophils, and basophils), and agranulocytes (monocytes, and lymphocytes (T cells and B cells)). Myeloid cells ( myelocytes) include neutrophils, eosinophils, mast cells, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Red Blood Cell
Red blood cells (RBCs), also referred to as red cells, red blood corpuscles (in humans or other animals not having nucleus in red blood cells), haematids, erythroid cells or erythrocytes (from Greek ''erythros'' for "red" and ''kytos'' for "hollow vessel", with ''-cyte'' translated as "cell" in modern usage), are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues—via blood flow through the circulatory system. RBCs take up oxygen in the lungs, or in fish the gills, and release it into tissues while squeezing through the body's capillaries. The cytoplasm of a red blood cell is rich in hemoglobin, an iron-containing biomolecule that can bind oxygen and is responsible for the red color of the cells and the blood. Each human red blood cell contains approximately 270 million hemoglobin molecules. The cell membrane is composed of proteins and lipids, and this structure provides properties essential for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MCD Peptide
Mast cell degranulating (MCD) peptide is a cationic 22-amino acid residue peptide, which is a component of the venom of the bumblebee (''Megabombus pennsylvanicus''). At low concentrations, MCD peptide can stimulate mast cell degranulation. At higher concentrations, it has anti-inflammatory properties. In addition, it is a potent blocker of voltage-sensitive potassium channels. Sources MCD peptide is a component of bumblebee (''Megabombus pennsylvanicus'') venom. In addition to MCD peptide, melittin and apamin have also been identified in this venom and are also described as voltage-dependent channel blockers. MCD peptide is also present in the venom of the honey bee ''Apis mellifera''. Chemistry MCD peptide is a cationic 22-amino acid residue peptide with two disulfide bridges. Although the MCD peptide sequence shows similarity with apamin, they have different toxic properties. MCD peptide belongs to a large family composed of numerous derivatives detecting specific target ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apamin
Apamin is an 18 amino acid globular peptide neurotoxin found in apitoxin (bee venom). Dry bee venom consists of 2–3% of apamin. Apamin selectively blocks SK channels, a type of Ca2+-activated K+ channel expressed in the central nervous system. Toxicity is caused by only a few amino acids, in particular cysteine1, lysine4, arginine13, arginine14 and histidine18. These amino acids are involved in the binding of apamin to the Ca2+-activated K+ channel. Due to its specificity for SK channels, apamin is used as a drug in biomedical research to study the electrical properties of SK channels and their role in the afterhyperpolarizations occurring immediately following an action potential. Origin The first symptoms of apitoxin (bee venom), that are now thought to be caused by apamin, were described back in 1936 by Hahn and Leditschke. Apamin was first isolated by Habermann in 1965 from ''Apis mellifera'', the Western honey bee. Apamin was named after this bee. Bee venom contains many o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Melittin
Melittin is the main component (40–60% of the dry weight) and the major pain producing substance of honeybee (''Apis mellifera'') venom. Melittin is a basic peptide consisting of 26 amino acids. Function The principal function of melittin as a component of bee venom is to cause pain and destruction of tissue of intruders that threaten a beehive. However, in honey bees, melittin is not only expressed in the venom gland, but also in other tissues when infected with pathogens. The two venom molecules, melittin and secapin, that are over-expressed in honey bees infected with various pathogens, possibly indicate a role for melittin in the immune response of bees to infectious diseases. Structure Melittin is a small peptide with no disulfide bridge; the ''N''-terminal part of the molecule is predominantly hydrophobic and the ''C''-terminal part is hydrophilic and strongly basic. In water, it forms a tetramer but it also can spontaneously integrate itself into cell membranes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Venom
Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved ''venom apparatus'', such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism. Venom has evolved in terrestrial and marine environments and in a wide variety of animals: both predators and prey, and both vertebrates and invertebrates. Venoms kill through the action of at least four major classes of toxin, namely necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; myotoxins, which damage muscles; and haemotoxins, which disrupt blood clotting. Venomous animals cause tens of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peptide
Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A polypeptide is a longer, continuous, unbranched peptide chain. Hence, peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. A polypeptide that contains more than approximately 50 amino acids is known as a protein. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, or to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthophora Urbana
The bee genus ''Anthophora'' is one of the largest in the family Apidae, with over 450 species worldwide in 14 different subgenera. They are most abundant and diverse in the Holarctic and African biogeographic regions. All species are solitary, though many nest in large aggregations. Nearly all species make nests in the soil, either in banks or in flat ground; the larvae develop in cells with waterproof linings and do not spin Pupa#Cocoon, cocoons. Males commonly have pale white or yellow facial markings, and/or peculiarly modified leg armature and hairs. ''Anthophora'' individuals can be distinguished from the very similar genus ''Amegilla'' by the possession of an arolium between the arthropod leg, tarsal claws. Species include: *''Anthophora bimaculata'' *''Anthophora curta'' *''Anthophora dispar'' *''Anthophora edwardsii'' *''Anthophora fedorica'' *''Anthophora flexipes'' *''Anthophora urbana'' *''Anthophora furcata'' *''Anthophora plumipes'' *''Anthophora pueblo'' *''Anthophor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mischocyttarus Flavitarsis
''Mischocyttarus flavitarsis'' is a social paper wasp found in western North America. Their nests can be found both in forests close to rivers or in close proximity to human life under the eaves of roofs. Despite the fact that ''M. flavitarsis ''nests are frequently in close contact with humans, ''M. flavitarsis'' typically will not sting, but rather ram into the threatening individual. Their colony cycle typically begins before May and will last until October. The queen will then seek a hibernation site for the winter. Perched near female hibernation sites are males with whom the female will mate. The males have claimed their territory by rubbing sternal brushes along the border of the site, leaving a chemical that deters other individuals from approaching. ''M. flavitarsis'' feed on arthropods, nectar, and animal carcasses and are often prey to birds, ants, and praying mantis. Taxonomy and phylogenetics Henri Louis Frédéric de Saussure, a Swiss mineralogist and entomologist, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
