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Savior Sibling
A savior baby or savior sibling is a child who is conceived in order to provide a stem cell transplant to a sibling that is affected with a fatal disease, such as cancer or Fanconi anemia, that can best be treated by hematopoietic stem cell transplantation. The savior sibling is conceived through in vitro fertilization. Fertilized zygotes are tested for genetic compatibility (human leukocyte antigen (HLA) typing), using preimplantation genetic diagnosis (PGD), and only zygotes that are compatible with the existing child are implanted. Zygotes are also tested to make sure they are free of the original genetic disease. The procedure is controversial. Indications A ''savior sibling'' may be the solution for any disease treated by hematopoietic stem cell transplantation. It is effective against genetically detectable (mostly monogenic) diseases, e.g. Fanconi anemia, Diamond–Blackfan anemia and β-thalassemia, in the ailing sibling, since the savior sibling can be selected to n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they can also have other causes. Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor diet, lack of physical activity or excessive drinking of alcohol. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. In the developing world, 15% of cancers are due to infections such as ''Helicobacter pylori'', hepatitis B, hepatitis C, human papillomavirus infection, Epstein–Barr virus and human immunodeficiency virus (HIV). These factors act, at least partly, by changing the genes of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infertility Treatment Authority
Infertility is the inability of a person, animal or plant to Sexual reproduction, reproduce by natural means. It is usually not the natural state of a healthy adult, except notably among certain eusocial species (mostly haplodiploid insects). It is the normal state of a human child or other young offspring, because they have not undergone puberty, which is the body's start of fertility, reproductive capacity. In humans, infertility is the inability to become pregnant after one year of unprotected and regular sexual intercourse involving a male and female partner.Chowdhury SH, Cozma AI, Chowdhury JH. Infertility. Essentials for the Canadian Medical Licensing Exam: Review and Prep for MCCQE Part I. 2nd edition. Wolters Kluwer. Hong Kong. 2017. There are many causes of infertility, including some that Assisted reproductive technology, medical intervention can treat. Estimates from 1997 suggest that worldwide about five percent of all heterosexual couples have an unresolved problem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trip Tucker
Charles "Trip" Tucker III, portrayed by Connor Trinneer, is a fictional character in the television series ''Star Trek: Enterprise''. Tucker was the chief engineer on the ''Enterprise'' and also briefly served in the same role aboard the Enterprise's sister ship '' Columbia''. Biography Tucker was born in 2121. His nickname "Trip" is short for "Triple", as he is the third generation of his family to be named Charles Tucker. He first met Jonathan Archer around (2143) a decade prior to the launch of ''Enterprise'' when the two worked together on an early warp 2 prototype vessel using the warp engine designed by Archer's father, Henry Archer. Tucker joined Starfleet in 2139. While a knowledgeable engineer, Tucker can be rash and "illogical", an opinion that early on causes friction between ''Enterprises Vulcan science officer, T'Pol and him. During the first year of ''Enterprise'''s mission, he finds himself coping with situations with which no Starfleet engineer has ever coped ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enterprise
Enterprise (or the archaic spelling Enterprize) may refer to: Business and economics Brands and enterprises * Enterprise GP Holdings, an energy holding company * Enterprise plc, a UK civil engineering and maintenance company * Enterprise Products, a natural gas and crude oil pipeline company * Enterprise Records, a record label * Enterprise Rent-A-Car, a car rental Provider **Enterprise Holdings, the parent company General * Business, economic activity done by a businessperson * Big business, larger corporation commonly called "enterprise" in business jargon (excluding small and medium sized businesses) * Company, a legal entity practicing a business activity * Enterprises in the Soviet Union, the equivalent of "company" in the former socialist state * Enterprise architecture, a strategic management discipline within an organization * Enterprise Capital Fund, a type of venture capital in the UK * Entrepreneurship, the practice of starting new organizations, particularl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mohinder Suresh
Mohinder Suresh is a fictional character on the NBC drama ''Heroes'', portrayed by Sendhil Ramamurthy. He is from Chennai, Tamil Nadu, India and is a genetics professor at the University of Madras holding a PhD in parapsychology. He is attempting to find the truth behind the sudden death of his father, Chandra Suresh (portrayed by Erick Avari), and to continue his father's research, finding the 'superhuman' beings on Earth. In character, Suresh also provides many episodes with opening and/or closing dialogue, generally philosophical musings regarding the events that take place during the episode. The role of Mohinder was originally written to be a 55-year-old geneticist looking for super powered humans. However, Sendhil Ramamurthy's audition was so convincing that the main character part was rewritten to be a younger geneticist following in his father's footsteps. The concept of the older geneticist was spun off into the minor, yet central, character of Chandra Suresh. Cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heroes (U
Heroes or Héroes may refer to: * Hero, one who displays courage and self-sacrifice for the greater good Film * ''Heroes'' (1977 film), an American drama * ''Heroes'' (2008 film), an Indian Hindi film Gaming * ''Heroes of Might and Magic'' or ''Heroes'', a series of video games *''Heroes of the Storm'' or ''Heroes,'' a 2015 video game * ''Heroes'' (role-playing game) (1979) * '' Heros: The Sanguine Seven'', a 1993 video game * ''Sonic Heroes'', a 2003 video game in the ''Sonic the Hedgehog'' franchise Literature * ''Heroes'' (book series), short novels and plays intended for young boys * ''Heroes'' (comics), a 1996 comic book by DC Comics * ''Heroes'' (novel), a 1998 novel by Robert Cormier * ''Heroes'' (play), a translation by Tom Stoppard of ''Le Vent Des Peupliers'' by Gérald Sibleyras * '' Heroes: Saving Charlie'', a 2007 novel based on the American TV series ''Heroes'' * ''Heroes'', a role-playing game magazine by Avalon Hill * ''Heroes'', a 2018 collection of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Crime Scene Investigation
Crime scene investigation may refer to: * Forensic inspection of a crime scene * ''CSI: Crime Scene Investigation'' (2000-2015), a US television series * ''CSI: Crime Scene Investigation'' (video game), a 2003 videogame based on the TV show * ''CSI'' (franchise), aka ''Crime Scene Investigation''; a US TV franchise, including CSI (2000-2015) See also * Crime scene investigator Forensic science, also known as criminalistics, is the application of science to criminal and civil laws, mainly—on the criminal side—during criminal investigation, as governed by the legal standards of admissible evidence and criminal p ... * CSI (other) {{Disambig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Debbie Dingle
Debbie Dingle (also Jones and Barton) is a fictional character from the British ITV soap opera ''Emmerdale'', played by Charley Webb. Webb has taken maternity leave three times, with the first time being in 2010 and the second throughout 2016 with Debbie departing on 1 January 2016. She returned on 24 January 2017 and then went on maternity leave for a third time in 2019 as Debbie left for Scotland on 13 August 2019. She returned for a short stint on 25 December 2020 and made her final appearance on 11 February 2021. She was introduced as the foster child of Paddy Kirk (Dominic Brunt) and Emily Kirk (Kate McGregor) before being revealed as the daughter of Charity Dingle (Emma Atkins) and Cain Dingle (Jeff Hordley). She has featured in many storylines on ''Emmerdale'' including her relationships with Andy Sugden (Kelvin Fletcher), which lead to her pregnancy at 15, Jasmine Thomas (Jenna-Louise Coleman) and Scott Windsor ( Ben Freeman), her daughter Sarah being diagnosed with a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emmerdale
''Emmerdale'' (known as ''Emmerdale Farm'' until 1989) is a British soap opera that is broadcast on ITV1. The show is set in Emmerdale (known as Beckindale until 1994), a fictional village in the Yorkshire Dales. Created by Kevin Laffan, ''Emmerdale Farm'' was first broadcast on 16 October 1972. Interior scenes have been filmed at the Leeds Studios since its inception. Exterior scenes were first filmed in Arncliffe in Littondale, and the series may have taken its name from Amerdale, an ancient name of Littondale. Exterior scenes were later shot at Esholt, but are now shot at a purpose-built set on the Harewood estate. The programme is broadcast in every ITV region. The series originally aired during the afternoon and was intended to be a three-month television series. However, more episodes were ordered and transmitted during the daytime until 1978, when it was moved to an early-evening prime time slot in most regions. In the late 1980s, the soap was met with a new produ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acute Promyelocytic Leukemia
Acute promyelocytic leukemia (APML, APL) is a subtype of acute myeloid leukemia (AML), a cancer of the white blood cells. In APL, there is an abnormal accumulation of immature granulocytes called promyelocytes. The disease is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene and is distinguished from other forms of AML by its responsiveness to all-''trans'' retinoic acid (ATRA; also known as tretinoin) therapy. Acute promyelocytic leukemia was first characterized in 1957 by French and Norwegian physicians as a hyperacute fatal illness, with a median survival time of less than a week. Today, prognoses have drastically improved; 10-year survival rates are estimated to be approximately 80-90% according to one study. Signs and symptoms The symptoms tend to be similar to AML in general with the following being possible symptoms: * Anemia * Fatigue * Weakness * Chills * Depression * Difficulty breathing (dyspnea) * Low platelets (thr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
My Sister's Keeper (film)
''My Sister's Keeper'' is a 2009 American drama film directed by Nick Cassavetes and starring Cameron Diaz, Abigail Breslin, Sofia Vassilieva, Jason Patric, and Alec Baldwin. Based on Jodi Picoult's 2004 novel of the same name, on June 26, 2009, the film was released to cinemas in the United States, Canada, Ireland, Mexico, and the United Kingdom. Plot Conceived via in vitro fertilization, 11-year old Anna Fitzgerald was born as a savior sister for her 15-year-old sister, Kate, who has acute promyelocytic leukemia, as neither her parents, firefighter Brian and lawyer Sara, nor younger brother Jesse are a genetic match. Beginning with the harvest of her umbilical cord at birth, Anna has donated compatible blood and stem cells to Kate, and her life is one of hospitalizations, growth hormone injections, opioid painkillers, sleeping pills, bleeding, and infections. Sara has no qualms over using Anna's body to treat Kate's, and fully believes she is doing so willingly, while Brian is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
