SMCO3 Tertiary2
Single-pass membrane and coiled-coil domain-containing protein 3 is a protein that is encoded in humans by the ''SMCO3'' gene. Gene Aliases ''SMCO3'' has 2 aliases, C12orf69 and LOC440087. Location ''SMCO3'' is located on the negative strand of chromosome 12 (12p12.3) and spans 10,460 base pairs (chr12:14,803,723-14,814,182). It has 2 exons that flank a single intron. Gene Neighborhood ''SMCO3'' is flanked by WW domain binding protein 11 (WBP11) and Ecto-ADP-ribosyltransferase 4 (ART4) on the minus strand and overlaps with C12orf60 on the plus strand. There is only a single isoform of this gene. Expression ''SMCO3'' is expressed in very low levels in several different human tissues including cervix, connective tissue, eye, lung and prostate. This highest expression of ''SMCO3'' is seen in the kidney, liver and spleen. ''SMCO3'' is also expressed at higher levels in cancers, especially chondrosarcoma and clear-cell renal cell carcinoma. ''SMCO3'' expression is on ...
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