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Roy Yorke Calne
Sir Roy Yorke Calne, FRCP, FRCS, FRS (born 30 December 1930) is a British surgeon and pioneer in organ transplantation. Career His most notable achievements are the world's first liver, heart, and lung transplant together with John Wallwork in 1987; the first successful combined stomach, intestine, pancreas, liver, and kidney cluster transplant in 1994, the first liver transplantation operation in Europe in 1968, and the first intestinal transplant in the UK in 1992. Calne is a fellow of the Royal Society and was Professor of Surgery at Cambridge University between 1965 and 1998 where he initiated the kidney transplant program. He was Harkness Fellow at Harvard Medical School from 1960 to 1961. Much of his subsequent work has been concerned with the improvement of immunosuppression techniques aimed at prolonging the life of liver transplant recipients. He is currently the Yoah Ghim Professor of Surgery at the National University of Singapore. Awards and honours He was elec ...
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Laurence Broderick
Laurence Broderick, , is a British sculptor. His best known work is 'The Bull', a public sculpture erected in 2003 at the Bull Ring, Birmingham. ''The Bull'' is about 4.5 meters long, about 190 cm high and weighs about 6.5 tons. It is one of the largest bronze animal sculptures in the country. His work consists largely of figurative carvings in stone and editions in bronze. Early life Broderick was born in Bristol, in the west of England, in 1935, and attended Bembridge School on the Isle of Wight. He studied painting, illustration and sculpture under Ray Millard and Geoffrey Deeley at the Regent Street Polytechnic from 1952 to 1957, and with Sidney Harpley and Keith Godwin at the Hammersmith School of Art from 1964 to 1965. Career Broderick began his artistic career as an historical and educational illustrator and painter. He taught Art at the Haberdashers' Aske's School in Cricklewood from 1959 and Elstree from 1961, and was Director of Art there from 1965 to 198 ...
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John Wallwork (surgeon)
John Wallwork CBE FRCS FMedSci (born July 1946), is a retired cardiothoracic surgeon and emeritus professor who performed Europe's first successful combined heart-lung transplant in 1984, and in 1986 performed the world's first heart-lung and liver transplant with Sir Roy Calne. In 2014, he became Chairman of Royal Papworth Hospital Royal Papworth Hospital is a specialist heart and lung hospital, located on the Cambridge Biomedical Campus in Cambridgeshire, England. The Hospital is run by Royal Papworth Hospital NHS Foundation Trust. The hospital is a world-leading cardiot .... He was President of the International Society for Heart and Lung Transplantation (ISHLT) 1994–1995. Wallwork is a Distinguished Supporter of Humanists UK. References Living people 1946 births British cardiac surgeons British thoracic surgeons British transplant surgeons Commanders of the Order of the British Empire Fellows of the Academy of Medical Sciences (United Kingdom) Fellows ...
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Knight Bachelor
The title of Knight Bachelor is the basic rank granted to a man who has been knighted by the monarch but not inducted as a member of one of the organised orders of chivalry; it is a part of the British honours system. Knights Bachelor are the most ancient sort of British knight (the rank existed during the 13th-century reign of King Henry III), but Knights Bachelor rank below knights of chivalric orders. A man who is knighted is formally addressed as "Sir irst Name urname or "Sir irst Name and his wife as "Lady urname. Criteria Knighthood is usually conferred for public service; amongst its recipients are all male judges of His Majesty's High Court of Justice in England. It is possible to be a Knight Bachelor and a junior member of an order of chivalry without being a knight of that order; this situation has become rather common, especially among those recognized for achievements in entertainment. For instance, Sir Michael Gambon, Sir Derek Jacobi, Sir Anthony Hopkins ...
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Royal College Of Surgeons Of England
The Royal College of Surgeons of England (RCS England) is an independent professional body and registered charity that promotes and advances standards of surgical care for patients, and regulates surgery and dentistry in England and Wales. The College is located at Lincoln's Inn Fields in London. It publishes multiple medical journals including the '' Annals of the Royal College of Surgeons of England'', the ''Faculty Dental Journal'', and the ''Bulletin of the Royal College of Surgeons of England''. History The origins of the college date to the fourteenth century with the foundation of the "Guild of Surgeons Within the City of London". Certain sources date this as occurring in 1368. There was ongoing dispute between the surgeons and barber surgeons until an agreement was signed between them in 1493, giving the fellowship of surgeons the power of incorporation. This union was formalised further in 1540 by Henry VIII between the Worshipful Company of Barbers (incorporat ...
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National University Of Singapore
The National University of Singapore (NUS) is a national public research university in Singapore. Founded in 1905 as the Straits Settlements and Federated Malay States Government Medical School, NUS is the oldest autonomous university in the country. It offers degree programmes in a wide range of disciplines at both the undergraduate and postgraduate levels, including in the sciences, medicine and dentistry, design and environment, law, arts and social sciences, engineering, business, computing, and music. NUS is one of the most highly-ranked academic institutions in the world. It has consistently featured in the top 30 of the Quacquarelli Symonds (QS) World University Rankings and the Times Higher Education (THE) World University Rankings, and in the top 100 of the Academic Ranking of World Universities (ARWU). As of 2022-2023, NUS is 11th worldwide according to QS and 19th worldwide according to THE. NUS's main campus is located in the southwestern part of Singapore, ...
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Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. In general, deliberately induced immunosuppression is performed to prevent the body from rejecting an organ transplant. Additionally, it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, or Crohn's disease. This is typically done using medications, but may involve surgery ( splenectomy), plasmapheresis, or radiation. A person who is undergoing immunosuppression, or whose immune system is weak for some other reasons (such as chemotherapy or HIV), is said to be '' immunocompromised''. Deliberately induced Administration of immunosuppressive me ...
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Harvard Medical School
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consistently ranked first for research among medical schools by '' U.S. News & World Report''. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital. History Harvard Medical School was founded on September 19, 1782, after President Joseph Willard presented a report w ...
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Harkness Fellow
The Harkness Fellowship (previously known as the Commonwealth Fund Fellowship) is a program run by the Commonwealth Fund of New York City. This fellowship was established to reciprocate the Rhodes Scholarships and enable Fellows from several countries to spend time studying in the United States. Recipients of the scholarship include a president of the International Court of Justice; former Chairman and CEO of Salomon Brothers; a former Vice-Chancellor of the University of Cambridge; the controller of BBC Radio 4; the editor of the ''Sunday Times''; former directors of the Medical Research Council, the London School of Economics and the General Medical Council; and a vice president of Microsoft. History The Commonwealth Fund is a philanthropic foundation established in the United States by Anna Harkness in 1918. Her son, Edward Stephen Harkness, initiated the Commonwealth Fund Fellowships in 1925. These were intended to reciprocate the Rhodes Scholarships by enabling British ...
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University Of Cambridge
The University of Cambridge is a public collegiate research university in Cambridge, England. Founded in 1209 and granted a royal charter by Henry III in 1231, Cambridge is the world's third oldest surviving university and one of its most prestigious, currently ranked second-best in the world and the best in Europe by '' QS World University Rankings''. Among the university's most notable alumni are 11 Fields Medalists, seven Turing Award winners, 47 heads of state, 14 British prime ministers, 194 Olympic medal-winning athletes,All Known Cambridge Olympians
. ''Hawks Club''. Retrieved 17 May 2019.
and some of world history's most transformational and iconic figures across disciplines, including
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Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the judges of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathematics, engineering science, and medical science". Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to many eminent scientists throughout history, including Isaac Newton (1672), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Albert Einstein (1921), Paul Dirac (1930), Winston Churchill (1941), Subrahmanyan Chandrasekhar (1944), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955) and Francis Crick (1959). More recently, fellowship has been awarded to Stephen Hawking (1974), David Attenborough (1983), Tim Hunt (1991), Elizabeth Blackburn (1992), Tim Berners-Lee (2001), Venki Ramakrishn ...
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Intestines
The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and other animals, including the esophagus, stomach, and intestines. Food taken in through the mouth is digested to extract nutrients and absorb energy, and the waste expelled at the anus as feces. ''Gastrointestinal'' is an adjective meaning of or pertaining to the stomach and intestines. Most animals have a "through-gut" or complete digestive tract. Exceptions are more primitive ones: sponges have small pores ( ostia) throughout their body for digestion and a larger dorsal pore ( osculum) for excretion, comb jellies have both a ventral mouth and dorsal anal pores, while cnidarians and acoels have a single pore for both digestion and excretion. The human gastrointestinal tract consists of the esophagus, stomach, and intestines, and is ...
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Liver Transplantation
Liver transplantation or hepatic transplantation is the replacement of a Liver disease, diseased liver with the healthy liver from another person (allograft). Liver transplantation is a treatment option for Cirrhosis, end-stage liver disease and acute liver failure, although availability of donor organs is a major limitation. The most common technique is orthotopic transplantation, in which the native liver is removed and replaced by the donor organ in the same anatomic position as the original liver. The surgical procedure is complex, requiring careful harvest of the donor organ and meticulous implantation into the recipient. Liver transplantation is highly regulated, and only performed at designated transplant medical centers by highly trained transplant physicians and supporting medical team. The duration of the surgery ranges from 4 to 18 hours depending on outcome. Favorable outcomes require careful screening for eligible recipient, as well as a well-calibrated live or cadave ...
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