Rossmann (supercomputer)
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Rossmann (supercomputer)
Rossmann is a supercomputer at Purdue University that went into production September 1, 2010. The high-performance computing cluster is operated by Information Technology at Purdue (ITaP), the university's central information technology organization. ITaP also operates clusters named Steele built in 2008, Coates built in 2009, Hansen built in the summer of 2011 and Carter built in the fall of 2012 in partnership with Intel. Rossmann ranked 126 on the November 2010 TOP500 list. Hardware The Rossmann cluster consists of HP ProLiant DL165 G7 compute nodes with 64-bit, dual 12-core AMD Opteron 6172 processors (24 cores per node), either 48 or 96 GB of memory and 250 GB of local disk for system software and scratch storage. Nodes with 192 GB of memory and either 1 terabyte or 2 TB of local scratch disk also are available. Rossmann consists of five logical sub-clusters, each with a different memory and storage configuration. All nodes have 10 Gigabit Ethernet interconnects. Software ...
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Supercomputer
A supercomputer is a computer with a high level of performance as compared to a general-purpose computer. The performance of a supercomputer is commonly measured in floating-point operations per second ( FLOPS) instead of million instructions per second (MIPS). Since 2017, there have existed supercomputers which can perform over 1017 FLOPS (a hundred quadrillion FLOPS, 100 petaFLOPS or 100 PFLOPS). For comparison, a desktop computer has performance in the range of hundreds of gigaFLOPS (1011) to tens of teraFLOPS (1013). Since November 2017, all of the world's fastest 500 supercomputers run on Linux-based operating systems. Additional research is being conducted in the United States, the European Union, Taiwan, Japan, and China to build faster, more powerful and technologically superior exascale supercomputers. Supercomputers play an important role in the field of computational science, and are used for a wide range of computationally intensive tasks in var ...
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Red Hat Enterprise Linux
Red Hat Enterprise Linux (RHEL) is a commercial open-source Linux distribution developed by Red Hat for the commercial market. Red Hat Enterprise Linux is released in server versions for x86-64, Power ISA, ARM64, and IBM Z and a desktop version for x86-64. Fedora Linux serves as its upstream source. All of Red Hat's official support and training, together with the Red Hat Certification Program, focuses on the Red Hat Enterprise Linux platform. The first version of Red Hat Enterprise Linux to bear the name originally came onto the market as "Red Hat Linux Advanced Server". In 2003, Red Hat rebranded Red Hat Linux Advanced Server to "Red Hat Enterprise Linux AS" and added two more variants, Red Hat Enterprise Linux ES and Red Hat Enterprise Linux WS. Red Hat uses strict trademark rules to restrict free re-distribution of their officially supported versions of Red Hat Enterprise Linux but still freely provides its source code. Third-party derivatives can be built and redistribut ...
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Los Angeles Times
The ''Los Angeles Times'' (abbreviated as ''LA Times'') is a daily newspaper that started publishing in Los Angeles in 1881. Based in the LA-adjacent suburb of El Segundo since 2018, it is the sixth-largest newspaper by circulation in the United States. The publication has won more than 40 Pulitzer Prizes. It is owned by Patrick Soon-Shiong and published by the Times Mirror Company. The newspaper’s coverage emphasizes California and especially Southern California stories. In the 19th century, the paper developed a reputation for civic boosterism and opposition to labor unions, the latter of which led to the bombing of its headquarters in 1910. The paper's profile grew substantially in the 1960s under publisher Otis Chandler, who adopted a more national focus. In recent decades the paper's readership has declined, and it has been beset by a series of ownership changes, staff reductions, and other controversies. In January 2018, the paper's staff voted to unionize and final ...
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Virus
A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsky's 1892 article describing a non-bacterial pathogen infecting tobacco plants and the discovery of the tobacco mosaic virus by Martinus Beijerinck in 1898,Dimmock p. 4 more than 9,000 virus species have been described in detail of the millions of types of viruses in the environment. Viruses are found in almost every ecosystem on Earth and are the most numerous type of biological entity. The study of viruses is known as virology, a subspeciality of microbiology. When infected, a host cell is often forced to rapidly produce thousands of copies of the original virus. When not inside an infected cell or in the process of infecting a cell, viruses exist in the form of independent particles, or ''virions'', consisting of (i) the genetic material, i. ...
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Rhinovirus
The rhinovirus (from the grc, ῥίς, rhis "nose", , romanized: "of the nose", and the la, vīrus) is the most common viral infectious agent in humans and is the predominant cause of the common cold. Rhinovirus infection proliferates in temperatures of 33–35 °C (91–95 °F), the temperatures found in the nose. Rhinoviruses belong to the genus ''Enterovirus'' in the family ''Picornaviridae''. The three species of rhinovirus (A, B, and C) include around 160 recognized types (called serotypes) of human rhinovirus that differ according to their surface antigens. They are lytic in nature and are among the smallest viruses, with diameters of about 30 nanometers. By comparison, other viruses, such as smallpox and vaccinia, are around ten times larger at about 300 nanometers, while flu viruses are around 80–120 nm. History In 1953, when a cluster of nurses developed a mild respiratory illness, Winston Price, from the Johns Hopkins University, took nasal pas ...
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Michael Rossmann
Michael G. Rossmann (30 July 1930 – 14 May 2019) was a German-American physicist, microbiologist, and Hanley Distinguished Professor of Biological Sciences at Purdue University who led a team of researchers to be the first to map the structure of a human common cold virus to an atomic level. He also discovered the Rossmann fold protein motif. His most well recognised contribution to structural biology is the development of a phasing technique named molecular replacement, which has led to about three quarters of depositions in the Protein Data Bank. Education Born in Frankfurt, Germany, Rossmann studied physics and mathematics at the University of London, where he received BSc and MSc degrees. He moved to Glasgow in 1953 where he taught physics in the technical college and received his Ph.D. in chemical crystallography in 1956. He attributes his initial interest in crystallography to Kathleen Lonsdale, whom he heard speak as a schoolboy. Rossmann began his career as a crystall ...
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DiaGrid (distributed Computing Network)
DiaGrid is a large, multicampus distributed research computing network utilizing the HTCondor system and centered at Purdue University in West Lafayette, Indiana. In 2012, it included nearly 43,000 processors representing 301 teraflops of computing power. DiaGrid received a Campus Technology Innovators Award from Campus Technology magazine and an IDG InfoWorld 100 Award in 2009 and was employed at the SC09 supercomputing conference in Portland, Ore., to capture nearly 150 days of compute time for science jobs. Partners DiaGrid is a partnership with Purdue, Indiana University, Indiana State University, the University of Notre Dame, the University of Louisville, the University of Nebraska, the University of Wisconsin, Purdue's Calumet and North Central campuses, and Indiana University-Purdue University Fort Wayne. It is designed to accommodate computers at other campuses as new members join. The Purdue portion of the pool, named BoilerGrid, is the largest academic system of its kind. ...
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Condor High-Throughput Computing System
HTCondor is an open-source software, open-source high-throughput computing software framework for coarse-grained distributed parallelization of computationally intensive tasks. It can be used to manage workload on a dedicated Computer cluster, cluster of computers, or to farm out work to idle desktop computersso-called CPU scavenging, cycle scavenging. HTCondor runs on Linux, Unix, Mac OS X, FreeBSD, and Microsoft Windows operating systems. HTCondor can integrate both dedicated resources (rack-mounted clusters) and non-dedicated desktop machines (cycle scavenging) into one computing environment. HTCondor is developed by the HTCondor team at the University of Wisconsin–Madison and is freely available for use. HTCondor follows an open-source software, open-source philosophy and is licensed under the Apache License 2.0. While HTCondor makes use of unused computing time, leaving computers turned on for use with HTCondor will increase energy consumption and associated costs. Star ...
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Open Science Grid Consortium
The Open Science Grid Consortium is an organization that administers a worldwide grid of technological resources called the Open Science Grid, which facilitates distributed computing for scientific research. Founded in 2004, the consortium is composed of service and resource providers, researchers from universities and national laboratories, as well as computing centers across the United States. Members independently own and manage the resources which make up the distributed facility, and consortium agreements provide the framework for technological and organizational integration. Use The OSG is used by scientists and researchers for data analysis tasks which are too computationally intensive for a single data center or supercomputer. While most of the grid's resources are used for particle physics, research teams from disciplines like biology, chemistry, astronomy, and geographic information systems are currently using the grid to analyze data. Research using the grid's resource ...
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Extreme Science And Engineering Discovery Environment
TeraGrid was an e-Science grid computing infrastructure combining resources at eleven partner sites. The project started in 2001 and operated from 2004 through 2011. The TeraGrid integrated high-performance computers, data resources and tools, and experimental facilities. Resources included more than a petaflops of computing capability and more than 30 petabytes of online and archival data storage, with rapid access and retrieval over high-performance computer network connections. Researchers could also access more than 100 discipline-specific databases. TeraGrid was coordinated through the Grid Infrastructure Group (GIG) at the University of Chicago, working in partnership with the resource provider sites in the United States. History The US National Science Foundation (NSF) issued a solicitation asking for a "distributed terascale facility" from program director Richard L. Hilderbrandt. The TeraGrid project was launched in August 2001 with $53 million in funding to four sites: ...
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National Science Foundation
The National Science Foundation (NSF) is an independent agency of the United States government that supports fundamental research and education in all the non-medical fields of science and engineering. Its medical counterpart is the National Institutes of Health. With an annual budget of about $8.3 billion (fiscal year 2020), the NSF funds approximately 25% of all federally supported basic research conducted by the United States' colleges and universities. In some fields, such as mathematics, computer science, economics, and the social sciences, the NSF is the major source of federal backing. The NSF's director and deputy director are appointed by the President of the United States and confirmed by the United States Senate, whereas the 24 president-appointed members of the National Science Board (NSB) do not require Senate confirmation. The director and deputy director are responsible for administration, planning, budgeting and day-to-day operations of the foundation, while t ...
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Grant (money)
A grant is a funding, fund given by an end entity grant – often a Government, public body, charitable foundation, or a specialised grant-making institution – to an individual or another entity (usually, a non-profit organisation, sometimes a business or a local government body) for a specific purpose linked to public benefit. Unlike loans, grants are not to be paid back. European Union European Union grants The European Commission provides financing through numerous specific calls for project proposals. These may be within Framework Programmes for Research and Technological Development, Framework Programmes. Although there are many 7-year programmes that are renewed that provide money for various purposes. These may be Structural Funds and Cohesion Fund, structural funds, Youth programmes and Educational policies and initiatives of the European Union, Education programmes. There are also occasional one-off grants to deal with unforeseen aspects or special projects and theme ...
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