Ralph (cloned Rat)
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Ralph (cloned Rat)
Ralph was the first cloned rat. To give birth to Ralph, 129 embryos were implanted into two females. One became pregnant and gave birth to three rats; Ralph was the first to be born. Ralph has been cloned for medical purposes requiring genetically identical animals including testing in impact of genetics and the environment in the development of many diseases, as well as to take away and modify genes, as well as to solve a problem with rat physiology. Cloned from an adult cell, Ralph was cloned by researchers from China and France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pac .... References {{reflist 2002 animal births 2002 in biotechnology 2002 in France Cloned animals Laboratory rats Individual animals in France Individual rodents Old World rats and mice Yvelines ...
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Rattus
''Rattus'' is a genus of muroid rodents, all typically called rats. However, the term rat can also be applied to rodent species outside of this genus. Species and description The best-known ''Rattus'' species are the black rat (''R. rattus'') and the brown rat (''R. norvegicus''). The group is generally known as the Old World rats or true rats and originated in Asia. Rats are bigger than most Old World mice, which are their relatives, but seldom weigh over in the wild. Taxonomy of ''Rattus'' The genus ''Rattus'' is a member of the giant subfamily Murinae. Several other murine genera are sometimes considered part of ''Rattus'': ''Lenothrix'', ''Anonymomys'', ''Sundamys'', ''Kadarsanomys'', ''Diplothrix'', ''Margaretamys'', ''Lenomys'', ''Komodomys'', ''Palawanomys'', ''Bunomys'', ''Nesoromys'', ''Stenomys'', ''Taeromys'', ''Paruromys'', ''Abditomys'', ''Tryphomys'', ''Limnomys'', ''Tarsomys'', '' Bullimus'', ''Apomys'', ''Millardia'', '' Srilankamys'', ''Niviventer'', ''Maxomy ...
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Jouy-en-Josas
Jouy-en-Josas () is a commune in the Yvelines department in the Île-de-France region in north-central France. It is located in the south-western suburbs of Paris, from the center of Paris. Jouy-en-Josas is home to the main campus of HEC School of Management. Geography Jouy-en-Josas is four kilometres to the south-east of Versailles, and 19r km to the south-west of Paris, in the middle of the valley of the Bièvre river. A town with nearly eight thousand inhabitants, half of Jouy-en-Josas is covered by forest. The communes that surround Jouy-en-Josas are Vélizy-Villacoublay, to the north-east, Bièvres to the east, Saclay to the south, Toussus-le-Noble to the extreme south-west, Les Loges-en-Josas to the west, Buc to the north-west and Versailles to the north-north-west. History ''Jouy'' is a direct translation of Latin '' gaudium'', both meaning "joy". Josas was the ancient name of an archdiaconate of the archbishop of Paris. Although many discoveries in var ...
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Cloning
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of Cell (biology), cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millio ...
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Embryo
An embryo is an initial stage of development of a multicellular organism. In organisms that reproduce sexually, embryonic development is the part of the life cycle that begins just after fertilization of the female egg cell by the male sperm cell. The resulting fusion of these two cells produces a single-celled zygote that undergoes many cell divisions that produce cells known as blastomeres. The blastomeres are arranged as a solid ball that when reaching a certain size, called a morula, takes in fluid to create a cavity called a blastocoel. The structure is then termed a blastula, or a blastocyst in mammals. The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. Gastrulation is the formation of the three germ layers that will form all of the different parts of the body. Neurulation forms the nervous ...
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Animal Testing
Animal testing, also known as animal experimentation, animal research, and ''in vivo'' testing, is the use of non-human animals in experiments that seek to control the variables that affect the behavior or biological system under study. This approach can be contrasted with field studies in which animals are observed in their natural environments or habitats. Experimental research with animals is usually conducted in universities, medical schools, pharmaceutical companies, defense establishments, and commercial facilities that provide animal-testing services to the industry. The focus of animal testing varies on a continuum from pure research, focusing on developing fundamental knowledge of an organism, to applied research, which may focus on answering some questions of great practical importance, such as finding a cure for a disease. Examples of applied research include testing disease treatments, breeding, defense research, and toxicology, including cosmetics testing. In edu ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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People's Republic Of China
China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and borders fourteen countries by land, the most of any country in the world, tied with Russia. Covering an area of approximately , it is the world's third largest country by total land area. The country consists of 22 provinces, five autonomous regions, four municipalities, and two Special Administrative Regions (Hong Kong and Macau). The national capital is Beijing, and the most populous city and financial center is Shanghai. Modern Chinese trace their origins to a cradle of civilization in the fertile basin of the Yellow River in the North China Plain. The semi-legendary Xia dynasty in the 21st century BCE and the well-attested Shang and Zhou dynasties developed a bureaucratic political system to serve hereditary monarchies, or dyna ...
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France
France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of Overseas France, overseas regions and territories in the Americas and the Atlantic Ocean, Atlantic, Pacific Ocean, Pacific and Indian Oceans. Its Metropolitan France, metropolitan area extends from the Rhine to the Atlantic Ocean and from the Mediterranean Sea to the English Channel and the North Sea; overseas territories include French Guiana in South America, Saint Pierre and Miquelon in the North Atlantic, the French West Indies, and many islands in Oceania and the Indian Ocean. Due to its several coastal territories, France has the largest exclusive economic zone in the world. France borders Belgium, Luxembourg, Germany, Switzerland, Monaco, Italy, Andorra, and Spain in continental Europe, as well as the Kingdom of the Netherlands, Netherlands, Suriname, and Brazil in the Americas via its overseas territories in French Guiana and Saint Martin (island), ...
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2002 In France
Events from the year 2002 in France. Incumbents * President: Jacques Chirac * Prime Minister: Lionel Jospin (until 7 May), Jean-Pierre Raffarin (starting 7 May) Events *1 January – the Euro replaces the French franc as France's currency. *6 March – France agrees to return the remains of Saartjie Baartman to South Africa. *21 April – first round of the presidential election: Jacques Chirac and Jean-Marie le Pen poll the most votes. Two weeks of demonstrations against the National Front follow. *5 May – second round of the presidential election. Jacques Chirac returns for a second term as President of the French Republic. *6 May – nomination of Jean-Pierre Raffarin for the post of Prime Minister. *9 June – first round of the legislative elections *16 June – second round of legislative elections. *14 July – During Bastille Day celebrations, Jacques Chirac escapes an assassination attempt unscathed. *November – Citroën launches a revised model of its popular Be ...
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Cloned Animals
Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, cloning is the process of creating cloned organisms (copies) of cells and of DNA fragments (molecular cloning). Etymology Coined by Herbert J. Webber, the term clone derives from the Ancient Greek word (), ''twig'', which is the process whereby a new plant is created from a twig. In botany, the term ''lusus'' was used. In horticulture, the spelling ''clon'' was used until the early twentieth century; the final ''e'' came into use to indicate the vowel is a "long o" instead of a "short o". Since the term entered the popular lexicon in a more general context, the spelling ''clone'' has been used exclusively. Natural cloning Cloning is a natural form of reproduction that has allowed life forms to spread for hundreds of millions of years. I ...
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