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Rabies
Rabies is a viral disease that causes encephalitis in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness. Once symptoms appear, the result is virtually always death, regardless of treatment. The time period between contracting the disease and the start of symptoms is usually one to three months but can vary from less than one week to more than one year. The time depends on the distance the virus must travel along peripheral nerves to reach the central nervous system. Rabies is caused by lyssaviruses, including the rabies virus and Australian bat lyssavirus. It is spread when an infected animal bites or scratches a human or other animals. Saliva from an infected animal can also transmit rabies if the saliv ...
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Rabies Vaccine
The rabies vaccine is a vaccine used to prevent rabies. There are a number of rabies vaccines available that are both safe and effective. They can be used to prevent rabies before, and, for a period of time, after exposure to the rabies virus, which is commonly caused by a dog bite or a bat bite. Doses are usually given by injection into the skin or muscle. After exposure, the vaccination is typically used along with rabies immunoglobulin. It is recommended that those who are at high risk of exposure be vaccinated before potential exposure. Rabies vaccines are effective in humans and other animals, and vaccinating dogs is very effective in preventing the spread of rabies to humans. A long-lasting immunity to the virus develops after a full course of treatment. Rabies vaccines may be used safely by all age groups. About 35 to 45 percent of people develop a brief period of redness and pain at the injection site, and 5 to 15 percent of people may experience fever, headaches, or ...
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Rabies Vaccine
The rabies vaccine is a vaccine used to prevent rabies. There are a number of rabies vaccines available that are both safe and effective. They can be used to prevent rabies before, and, for a period of time, after exposure to the rabies virus, which is commonly caused by a dog bite or a bat bite. Doses are usually given by injection into the skin or muscle. After exposure, the vaccination is typically used along with rabies immunoglobulin. It is recommended that those who are at high risk of exposure be vaccinated before potential exposure. Rabies vaccines are effective in humans and other animals, and vaccinating dogs is very effective in preventing the spread of rabies to humans. A long-lasting immunity to the virus develops after a full course of treatment. Rabies vaccines may be used safely by all age groups. About 35 to 45 percent of people develop a brief period of redness and pain at the injection site, and 5 to 15 percent of people may experience fever, headaches, or ...
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Rabies Virus
Rabies virus, scientific name ''Rabies lyssavirus'', is a neurotropic virus that causes rabies in humans and animals. Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva. ''Rabies lyssavirus'', like many rhabdoviruses, has an extremely wide host range. In the wild it has been found infecting many mammalian species, while in the laboratory it has been found that birds can be infected, as well as cell cultures from mammals, birds, reptiles and insects. Rabies is reported in more than 150 countries on all continents, with the exclusion of Antarctica. The main burden of disease is reported in Asia and Africa, but some cases have been reported also in Europe in the past 10 years, especially in returning travellers. ''Rabies lyssavirus'' has a cylindrical morphology and is a member of the '' Lyssavirus'' genus of the ''Rhabdoviridae'' family. These viruses are enveloped and have a single stranded RNA genome with negative-s ...
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Rabies Virus
Rabies virus, scientific name ''Rabies lyssavirus'', is a neurotropic virus that causes rabies in humans and animals. Rabies transmission can occur through the saliva of animals and less commonly through contact with human saliva. ''Rabies lyssavirus'', like many rhabdoviruses, has an extremely wide host range. In the wild it has been found infecting many mammalian species, while in the laboratory it has been found that birds can be infected, as well as cell cultures from mammals, birds, reptiles and insects. Rabies is reported in more than 150 countries on all continents, with the exclusion of Antarctica. The main burden of disease is reported in Asia and Africa, but some cases have been reported also in Europe in the past 10 years, especially in returning travellers. ''Rabies lyssavirus'' has a cylindrical morphology and is a member of the '' Lyssavirus'' genus of the ''Rhabdoviridae'' family. These viruses are enveloped and have a single stranded RNA genome with negative-s ...
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Rabies Immunoglobulin
Rabies immunoglobulin (RIG) is a medication made up of antibodies against the rabies virus. It is used to prevent rabies following exposure. It is given after the wound is cleaned with soap and water or povidone-iodine and is followed by a course of rabies vaccine. It is given by injection into the site of the wound and into a muscle. It is not needed in people who have been previously vaccinated against rabies. Common side effects include pain at the site of injection, fever, and headache. Severe allergic reactions such as anaphylaxis may rarely occur. Use during pregnancy is not known to harm the baby. It works by binding to the rabies virus before it can enter nerve tissue. After the virus has entered the central nervous system, rabies immunoglobulin is no longer useful. The use of rabies immunoglobulin in the form of blood serum dates from 1891. Use became common within medicine in the 1950s. It is on the World Health Organization's List of Essential Medicines. Rabies ...
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Lyssavirus
''Lyssavirus'' (from the Ancient Greek, Greek ''lyssa'' "rage, fury, rabies" and the Latin ''Virus#Etymology, vÄ«rus'') is a genus of RNA viruses in the family ''Rhabdoviridae'', order ''Mononegavirales''. Mammals, including humans, can serve as natural hosts. The genus ''Lyssavirus'' includes the rabies virus traditionally associated with rabies, the disease of the same name. Taxonomy Virology Structure Lyssavirions are enveloped, with bullet shaped geometries. These virions are about 75 nm wide and 180 nm long. Lyssavirions have helical symmetry, so their infectious particles are approximately cylindrical in shape. This is typical of plant-infecting viruses. Virions of human-infecting viruses more commonly have cubic symmetry and take shapes approximating regular polyhedron, regular polyhedra. The structure consists of a spiked outer envelope (biology), envelope, a middle region consisting of matrix protein M, and an inner ribonucleocapsid complex region, con ...
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Dog Bites
A dog bite is a bite upon a person or other animal by a dog, including from a rabid dog. More than one successive bite is often called a dog attack, although dog attacks can include knock-downs and scratches. Though some dog bites do not result in injury, they can result in infection, disfigurement, temporary or permanent disability, or death. Another type of dog bite is the "soft bite" displayed by well-trained dogs, by puppies, and in non-aggressive play. Dog bites can occur during dog fighting, as a response to mistreatment, trained dogs working as guard, police or military animals, or during a random encounter. There is debate on whether or not certain breeds of dogs are inherently more prone to commit attacks causing serious injury (i.e., so driven by instinct and breeding that, under certain circumstances, they are exceedingly likely to attempt or commit dangerous attacks). It is recognized that the risk of dog bites can be increased by human actions such as abuse or ...
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Australian Bat Lyssavirus
''Australian bat lyssavirus'' (''ABLV''), originally named ''Pteropid lyssavirus'' (''PLV''), is a zoonotic virus closely related to the rabies virus. It was first identified in a 5-month-old juvenile black flying fox ('' Pteropus alecto'') collected near Ballina in northern New South Wales, Australia, in January 1995 during a national surveillance program for the recently identified Hendra virus. ABLV is the seventh member of the genus '' Lyssavirus'' (which includes ''Rabies virus'') and the only ''Lyssavirus'' member present in Australia. Prevalence ABLV is distributed throughout Australia in a variety of bat species which are believed to be the primary reservoir for the virus. Surveillance initiatives also confirmed the presence of lyssavirus in both Pteropid (Gould ''et al.''., 1998) and insectivorous bats (Gould ''et al.''., 2002; Hooper ''et al.''., 1997), and later, human infections were reported following encounters with both fruit and insectivorous bats (Allworth ''e ...
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Vampire Bat
Vampire bats, species of the subfamily Desmodontinae, are leaf-nosed bats found in Central and South America. Their food source is blood of other animals, a dietary trait called hematophagy. Three extant bat species feed solely on blood: the common vampire bat (''Desmodus rotundus''), the hairy-legged vampire bat (''Diphylla ecaudata''), and the white-winged vampire bat (''Diaemus youngi''). All three species are native to the Americas, ranging from Mexico to Brazil, Chile, Uruguay and Argentina. Taxonomy Due to differences among the three species, each has been placed within a different genus, each consisting of one extant species. In the older literature, these three genera were placed within a family of their own, Desmodontidae, but taxonomists have now grouped them as a subfamily, Desmodontinae, in the New World leaf-nosed bat family, Phyllostomidae. The three known species of vampire bats all seem more similar to one another than to any other species. That suggests th ...
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Encephalitis
Encephalitis is inflammation of the brain. The severity can be variable with symptoms including reduction or alteration in consciousness, headache, fever, confusion, a stiff neck, and vomiting. Complications may include seizures, hallucinations, trouble speaking, memory problems, and problems with hearing. Causes of encephalitis include viruses such as herpes simplex virus and rabies virus as well as bacteria, fungi, or parasites. Other causes include autoimmune diseases and certain medications. In many cases the cause remains unknown. Risk factors include a weak immune system. Diagnosis is typically based on symptoms and supported by blood tests, medical imaging, and analysis of cerebrospinal fluid. Certain types are preventable with vaccines. Treatment may include antiviral medications (such as acyclovir), anticonvulsants, and corticosteroids. Treatment generally takes place in hospital. Some people require artificial respiration. Once the immediate problem is under co ...
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Viral Disease
A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. Structural Characteristics Basic structural characteristics, such as genome type, virion shape and replication site, generally share the same features among virus species within the same family. * Double-stranded DNA families: three are non-enveloped (''Adenoviridae'', '' Papillomaviridae'' and ''Polyomaviridae'') and two are enveloped (''Herpesviridae'' and ''Poxviridae''). All of the non-enveloped families have icosahedral capsids. * Partly double-stranded DNA viruses: '' Hepadnaviridae''. These viruses are enveloped. * One family of single-stranded DNA viruses infects humans: '' Parvoviridae''. These viruses are non-enveloped. * Positive single-stranded RNA families: three non-enveloped ('' Astroviridae'', ''Caliciviridae'' and ''Picornaviridae'') and four enveloped ('' Coronaviridae'', '' Fl ...
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Nausea
Nausea is a diffuse sensation of unease and discomfort, sometimes perceived as an urge to vomit. While not painful, it can be a debilitating symptom if prolonged and has been described as placing discomfort on the chest, abdomen, or back of the throat. Over 30 definitions of nausea were proposed in a 2011 book on the topic. Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are gastroenteritis and other gastrointestinal disorders, food poisoning, motion sickness, dizziness, migraine, fainting, low blood sugar, anxiety, and lack of sleep. Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. Nausea may also be caused by disgust and depression. Medications taken to prevent and treat nausea and vomiting are called antiemetics. The most commonly prescribed antiemetics in the US are promethazine, metoclopramide, and the newer ondansetron. The word nausea is from L ...
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