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RAB9A
Ras-related protein Rab-9A is a protein that in humans is encoded by the ''RAB9A'' gene. Interactions RAB9A has been shown to interact with RABEPK, TIP47 and the Biogenesis of lysosome-related organelles complex 3 BLOC-3 or biogenesis of lysosome-related organelles complex 3 is a ubiquitously expressed multisubunit protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perfor .... References Further reading * * * * * * * * * * * * * * * * {{Gene-X-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RABEPK
Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the ''RABEPK'' gene. Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor ( MPR) from endosomes to the trans-Golgi network. Interactions RABEPK has been shown to interact with RAB9A Ras-related protein Rab-9A is a protein that in humans is encoded by the ''RAB9A'' gene. Interactions RAB9A has been shown to interact with RABEPK, TIP47 and the Biogenesis of lysosome-related organelles complex 3 BLOC-3 or biogenesis of lyso ... and FYVE finger-containing phosphoinositide kinase. References Further reading * * * * * * * External links * * {{gene-9-stub Kelch proteins ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TIP47
Mannose-6-phosphate receptor binding protein 1 (M6PRBP1) is a protein which in humans is encoded by the ''M6PRBP1'' gene. Its gene product, as well as the gene itself, is commonly known as TIP47. Function Mannose 6-phosphate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. The mannose-6-phosphate receptor-binding properties of TIP47 are disputed, despite the designation of M6PRBP1 as TIP47's gene symbol. TIP47 protein is most commonly described in the scientific literature as a coat protein for lipid droplets. TIP47 belongs to the peripilin protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid residue ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
