Rudolph Schönheimer
Rudolf Schoenheimer (May 10, 1898 – September 11, 1941) was a German-American biochemist who developed the technique of isotope labelling/''tagging'' of biomolecules, enabling detailed study of metabolism. This work revealed that all the constituents of an organism are in a constant state of chemical renewal. Born in Berlin, after graduating in medicine from the Friedrich Wilhelm University there, he learned further organic chemistry at the University of Leipzig and then studied biochemistry at the University of Freiburg where he rose to be Head of Physiological Chemistry. He spent the 1930-31 academic year at the University of Chicago. In 1933, following the rise of the Nazis to power he emigrated from Germany to the Columbia University to join the department of Biological Chemistry. Working with David Rittenberg, from the radiochemistry laboratory of Harold C. Urey and later together with Konrad Bloch, they used stable isotopes to ''tag'' foodstuffs and trace their met ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Berlin
Berlin ( , ) is the capital and largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's most populous city, according to population within city limits. One of Germany's sixteen constituent states, Berlin is surrounded by the State of Brandenburg and contiguous with Potsdam, Brandenburg's capital. Berlin's urban area, which has a population of around 4.5 million, is the second most populous urban area in Germany after the Ruhr. The Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's third-largest metropolitan region after the Rhine-Ruhr and Rhine-Main regions. Berlin straddles the banks of the Spree, which flows into the Havel (a tributary of the Elbe) in the western borough of Spandau. Among the city's main topographical features are the many lakes in the western and southeastern boroughs formed by the Spree, Havel and Dahme, the largest of which is Lake Müggelsee. Due to its l ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Konrad Bloch
Konrad Emil Bloch (; 21 January 1912 – 15 October 2000) was a German-American biochemist. Bloch received the Nobel Prize in Physiology or Medicine in 1964 (joint with Feodor Lynen) for discoveries concerning the mechanism and regulation of the cholesterol and fatty acid metabolism.Konrad E. Bloch Encyclopaedia Britannica Life and career Bloch was born in Neisse (Nysa), in the 's[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chemistry
Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during a Chemical reaction, reaction with other Chemical substance, substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both Basic research, basic and Applied science, applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth (botany), the formation of igneous rocks (geology), how atmospheric ozone is formed and how environmental pollutants are degraded (ecology), the properties ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Leipzig University
Leipzig University (german: Universität Leipzig), in Leipzig in Saxony, Germany, is one of the world's oldest universities and the second-oldest university (by consecutive years of existence) in Germany. The university was founded on 2 December 1409 by Frederick I, Elector of Saxony and his brother William II, Margrave of Meissen, and originally comprised the four scholastic faculties. Since its inception, the university has engaged in teaching and research for over 600 years without interruption. Famous alumni include Gottfried Wilhelm von Leibniz, Johann Wolfgang von Goethe, Leopold von Ranke, Friedrich Nietzsche, Robert Schumann, Richard Wagner, Tycho Brahe, Georgius Agricola, Angela Merkel and ten Nobel laureates associated with the university. History Founding and development until 1900 The university was modelled on the University of Prague, from which the German-speaking faculty members withdrew to Leipzig after the Jan Hus crisis and the Decree of Kutná Hora. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pathology
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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World War I
World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fighting occurring throughout Europe, the Middle East, Africa, the Pacific, and parts of Asia. An estimated 9 million soldiers were killed in combat, plus another 23 million wounded, while 5 million civilians died as a result of military action, hunger, and disease. Millions more died in genocides within the Ottoman Empire and in the 1918 influenza pandemic, which was exacerbated by the movement of combatants during the war. Prior to 1914, the European great powers were divided between the Triple Entente (comprising France, Russia, and Britain) and the Triple Alliance (containing Germany, Austria-Hungary, and Italy). Tensions in the Balkans came to a head on 28 June 1914, following the assassination of Archduke Franz Ferdin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Western Front (World War I)
The Western Front was one of the main theatres of war during the First World War. Following the outbreak of war in August 1914, the German Army opened the Western Front by invading Luxembourg and Belgium, then gaining military control of important industrial regions in France. The German advance was halted with the Battle of the Marne. Following the Race to the Sea, both sides dug in along a meandering line of fortified trenches, stretching from the North Sea to the Swiss frontier with France, which changed little except during early 1917 and in 1918. Between 1915 and 1917 there were several offensives along this front. The attacks employed massive artillery bombardments and massed infantry advances. Entrenchments, machine gun emplacements, barbed wire and artillery repeatedly inflicted severe casualties during attacks and counter-attacks and no significant advances were made. Among the most costly of these offensives were the Battle of Verdun, in 1916, with a combined 700,000 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Artillery
Artillery is a class of heavy military ranged weapons that launch munitions far beyond the range and power of infantry firearms. Early artillery development focused on the ability to breach defensive walls and fortifications during sieges, and led to heavy, fairly immobile siege engines. As technology improved, lighter, more mobile field artillery cannons developed for battlefield use. This development continues today; modern self-propelled artillery vehicles are highly mobile weapons of great versatility generally providing the largest share of an army's total firepower. Originally, the word "artillery" referred to any group of soldiers primarily armed with some form of manufactured weapon or armor. Since the introduction of gunpowder and cannon, "artillery" has largely meant cannons, and in contemporary usage, usually refers to shell-firing guns, howitzers, and mortars (collectively called ''barrel artillery'', ''cannon artillery'', ''gun artillery'', or - a layman t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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German Army
The German Army (, "army") is the land component of the armed forces of Germany. The present-day German Army was founded in 1955 as part of the newly formed West German ''Bundeswehr'' together with the ''Marine'' (German Navy) and the ''Luftwaffe'' (German Air Force). , the German Army had a strength of 62,766 soldiers. History Overview A German army equipped, organized, and trained following a single doctrine and permanently unified under one command in 1871 during the unification of Germany under the leadership of Prussia. From 1871 to 1919, the title '' Deutsches Heer'' (German Army) was the official name of the German land forces. Following the German defeat in World War I and the end of the German Empire, the main army was dissolved. From 1921 to 1935 the name of the German land forces was the ''Reichsheer'' (Army of the Empire) and from 1935 to 1945 the name '' Heer'' was used. The ''Heer'' was one of two ground forces of the Third Reich during World War II but, unlike t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Physician
A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the ''science'' of medicine—and also a decent competence in its applied practice—the art or ''craft'' of medicine. Both the role of the physician and the meaning ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Germany
Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated between the Baltic and North seas to the north, and the Alps to the south; it covers an area of , with a population of almost 84 million within its 16 constituent states. Germany borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The nation's capital and most populous city is Berlin and its financial centre is Frankfurt; the largest urban area is the Ruhr. Various Germanic tribes have inhabited the northern parts of modern Germany since classical antiquity. A region named Germania was documented before AD 100. In 962, the Kingdom of Germany formed the bulk of the Holy Roman Empire. During the 16th ce ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Cyanide
Cyanide is a naturally occurring, rapidly acting, toxic chemical that can exist in many different forms. In chemistry, a cyanide () is a chemical compound that contains a functional group. This group, known as the cyano group, consists of a carbon atom triple-bonded to a nitrogen atom. In inorganic cyanides, the cyanide group is present as the anion . Soluble salts such as sodium cyanide (NaCN) and potassium cyanide (KCN) are highly toxic. Hydrocyanic acid, also known as hydrogen cyanide, or HCN, is a highly volatile liquid that is produced on a large scale industrially. It is obtained by acidification of cyanide salts. Organic cyanides are usually called nitriles. In nitriles, the group is linked by a covalent bond to carbon. For example, in acetonitrile (), the cyanide group is bonded to methyl (). Although nitriles generally do not release cyanide ions, the cyanohydrins do and are thus rather toxic. Bonding The cyanide ion is isoelectronic with carbon monoxide a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |