Quiz Of God
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Quiz Of God
''Quiz of God'' () is a South Korean television series broadcast on cable channel OCN. It was the first medical/forensic crime investigation drama to air in Korea. The series follows genius but eccentric neurosurgeon and forensic doctor Han Jin-woo (played by Ryu Deok-hwan) and his team as they solve suspicious deaths and unravel mysteries involving rare diseases. The title refers to a local saying that rare diseases are like quizzes God gives to humans so as not to become too arrogant. The first season dealt mostly with inherited rare diseases including porphyria, phenylketonuria, muscular dystrophy, Guillain–Barré syndrome, reflex anoxic seizures and Savant syndrome. Fabry disease, Kleine–Levin syndrome and congenital insensitivity to pain with anhidrosis were featured in the second season. Series overview Cast Main * Ryu Deok-hwan as Jin-woo Han, neurosurgeon and forensic doctor * Yoon Joo-hee as Kyung-hee Kang, detective * Choi Jung-woo as Kyu-tae Jang * Park Jo ...
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Police Procedural
The police show, or police crime drama, is a subgenre of procedural drama and detective fiction that emphasizes the investigative procedure of a police officer or department as the protagonist(s), as contrasted with other genres that focus on either a private detective, an amateur investigator or the characters who are the targets of investigations. While many police procedurals conceal the criminal's identity until the crime is solved in the narrative climax (the so-called whodunit), others reveal the perpetrator's identity to the audience early in the narrative, making it an inverted detective story. Whatever the plot style, the defining element of a police procedural is the attempt to accurately depict the profession of law enforcement, including such police-related topics as forensic science, autopsies, gathering evidence, search warrants, interrogation and adherence to legal restrictions and procedure. Early history The roots of the police procedural have been traced to at l ...
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Forensic Pathology
Forensic pathology is pathology that focuses on determining the cause of death by examining a corpse. A post mortem examination is performed by a medical examiner or forensic pathologist, usually during the investigation of criminal law cases and civil law cases in some jurisdictions. Coroners and medical examiners are also frequently asked to confirm the identity of remains. Duties Forensic pathology is an application of medical jurisprudence. A forensic pathologist is a medical doctor who has completed training in anatomical pathology and has subsequently specialized in forensic pathology. The requirements for becoming a "fully qualified" forensic pathologist vary from country to country. Some of the different requirements are discussed below. The forensic pathologist performs autopsies/postmortem examinations with the goal determining the cause of death as well as the possible manner of death. The autopsy report contains conclusions made relating to the following: * The p ...
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Medical Examiner
The medical examiner is an appointed official in some American jurisdictions who is trained in pathology that investigates deaths that occur under unusual or suspicious circumstances, to perform post-mortem examinations, and in some jurisdictions to initiate inquests. In the US, there are two death investigation systems, the coroner system based on English law, and the medical examiner system, which evolved from the coroner system during the latter half of the 19th century. The type of system varies from municipality to municipality and from state to state, with over 2,000 separate jurisdictions for investigating unnatural deaths. In 2002, 22 states had a medical examiner system, 11 states had a coroner system, and 18 states had a mixed system. Since the 1940s, the medical examiner system has gradually replaced the coroner system, and serves about 48% of the US population. The coroner is not necessarily a medical doctor, but a lawyer, or even a layperson. In the 19th century, ...
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Korea Standard Time
South Korea has one time zone, Korea Standard Time ( UTC+09:00), which is abbreviated KST. South Korea currently does not observe daylight saving time, but experimented with it during the 1988 Summer Olympics in Seoul. History In 1434, inventor Jang Yeong-sil developed Korea's first automatic water clock, which King Sejong adapted as Korea's standard timekeeper. It is likely that Koreans used water clocks to keep time prior to this invention, but no concrete records of them exist. In 1437, Jang Yeong-sil, with Jeong Cho, created a bowl-shaped sundial called the ''angbu ilgu'' (Hangul: 앙부일구), which King Sejong had placed in public so anyone could use it. Geographically, the western parts of Korea, including the South Korean capital city, Seoul, are UTC+08:00. In 1908, the Korean Empire adopted a standard time that was hours ahead of GMT, UTC+08:30. In 1912, during the Japanese occupation of Korea, the Governor-General of Korea changed standard time to UTC+09:00 to a ...
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Anhidrosis
Hypohidrosis is a disorder in which a person exhibits diminished sweating in response to appropriate stimuli. In contrast with hyp''er''hidrosis, which is a socially troubling yet often benign condition, the consequences of untreated hypohidrosis include hyperthermia, heat stroke and death. An extreme case of hypohidrosis in which there is a complete absence of sweating and the skin is dry is termed anhidrosis. Causes Diagnosis Sweat is readily visualized by a topical indicator such as iodinated starch ( Minor test) or sodium alizarin sulphonate, both of which undergo a dramatic colour change when moistened by sweat. A thermoregulatory sweat test can evaluate the body’s response to a thermal stimulus by inducing sweating through a hot box ⁄ room, thermal blanket or exercise. Failure of the topical indicator to undergo a colour change during thermoregulatory sweat testing indicates hypohidrosis, and further tests may be required to localize the lesion. Magnetic resonance im ...
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Congenital Insensitivity To Pain
Congenital insensitivity to pain (CIP), also known as congenital analgesia, is one or more extraordinarily rare conditions in which a person cannot feel (and has never felt) physical pain. The conditions described here are separate from the HSAN group of disorders, which have more specific signs and cause. Because feeling physical pain is vital for survival, CIP is an extremely dangerous condition. It is common for people with the condition to die in childhood due to injuries or illnesses going unnoticed. Burn injuries are among the more common injuries. Signs and symptoms For people with this disorder, cognition and sensation are otherwise normal; for instance, patients can still feel discriminative touch (though not always temperature), and there are generally no detectable physical abnormalities. Because children and adults with the disorder cannot feel pain, they may not respond to problems, thus being at a higher risk of more severe diseases. Children with this condition ...
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Kleine–Levin Syndrome
Kleine–Levin syndrome (KLS) is a rare disorder characterized by persistent episodic hypersomnia and cognitive or mood changes. Many patients also experience hyperphagia, hypersexuality and other symptoms. Patients generally experience recurrent episodes of the condition for more than a decade and may return at a later age. Individual episodes generally last more than a week, sometimes lasting for months. The condition greatly affects the personal, professional, and social lives of those with KLS. The severity of symptoms and the course of the syndrome vary between those with KLS. Patients commonly have about 20 episodes over about a decade. Several months generally elapse between episodes. The onset of the condition usually follows a viral infection; several different viruses have been observed to trigger KLS. It is generally only diagnosed after similar conditions have been excluded; MRI, CT scans, lumbar puncture, and toxicology tests are used to rule out other possibilities. ...
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Fabry Disease
Fabry disease, also known as Anderson–Fabry disease, is a rare genetic disease that can affect many parts of the body, including the kidneys, heart, and skin. Fabry disease is one of a group of conditions known as lysosomal storage diseases. The genetic mutation that causes Fabry disease interferes with the function of an enzyme that processes biomolecules known as sphingolipids, leading to these substances building up in the walls of blood vessels and other organs. It is inherited in an X-linked manner. Fabry disease is sometimes diagnosed using a blood test that measures the activity of the affected enzyme called alpha-galactosidase, but genetic testing is also sometimes used, particularly in females. The treatment for Fabry disease varies depending on the organs affected by the condition, and the underlying cause can be addressed by replacing the enzyme that is lacking. The first descriptions of the condition were made simultaneously by dermatologist Johannes Fabry and ...
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Savant Syndrome
Savant syndrome () is a rare condition in which someone with significant mental disabilities demonstrates certain abilities far in excess of average. The skills that savants excel at are generally related to memory. This may include rapid calculation, artistic ability, map making, or musical ability. Usually, only one exceptional skill is present. Those with the condition generally have a neurodevelopmental disorder such as autism spectrum disorder or have a brain injury. About half of cases are associated with autism, and these individuals may be known as "autistic savants". While the condition usually becomes apparent in childhood, some cases develop later in life. It is not recognized as a mental disorder within the DSM-5. Savant syndrome is estimated to affect around one in a million people. The condition affects more males than females, at a ratio of 6:1. The first medical account of the condition was in 1783. Among those with autism, 1 in 10 to 1 in 200 have savant synd ...
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Reflex Asystolic Syncope
Reflex asystolic syncope (RAS) is a form of syncope encountered mainly, but not exclusively, in young children. Reflex anoxic seizures are not epileptic seizures or epilepsy. This is usually a consequence of a reduction in cerebral perfusion by oxygenated blood. It can be a result of either a sudden reduction in the blood flow to the brain, a drop in the oxygen content of the blood supplying the brain, or a combination of the two. Syncope can have different meanings ranging from transient loss of consciousness, usually accompanied by a decrease or loss in postural tone (the principal manifestations of "simple faints"), to tonic and myoclonic events and nonepileptic spasms. Signs and symptoms A minor bump to the head is the most commonly reported precipitant. Usually the toddler trips and falls; the child's caregiver may hear the bump. Most commonly, the child does not cry, although some parents give descriptions of the child "trying to cry" (Stephenson 1978), or there may be a ...
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Guillain–Barré Syndrome
Guillain–Barré syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system damaging the peripheral nervous system. Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. The symptoms may develop over hours to a few weeks. During the acute phase, the disorder can be life-threatening, with about 15% of people developing weakness of the breathing muscles and, therefore, requiring mechanical ventilation. Some are affected by changes in the function of the autonomic nervous system, which can lead to dangerous abnormalities in heart rate and blood pressure. Although the cause is unknown, the underlying mechanism involves an autoimmune disorder in which the body's immune system mistakenly attacks the peripheral nerves and damages their myelin insulation. Sometimes this immune dysfunction is trig ...
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Muscular Dystrophy
Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Some types are also associated with problems in other organs. Over 30 different disorders are classified as muscular dystrophies. Of those, Duchenne muscular dystrophy (DMD) accounts for approximately 50% of cases and affects males beginning around the age of four. Other relatively common muscular dystrophies include Becker muscular dystrophy, facioscapulohumeral muscular dystrophy, and myotonic dystrophy, whereas limb–girdle muscular dystrophy and congenital muscular dystrophy are themselves groups of several – usually ultrarare – genetic disorders. Muscular dystrophies are caused by mutations in genes, usually those involved in making muscle proteins. ...
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