QALYs
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QALYs
The quality-adjusted life year (QALY) is a generic measure of disease burden, including both the quality and the quantity of life lived. It is used in economic evaluation to assess the value of medical interventions. One QALY equates to one year in perfect health. QALY scores range from 1 (perfect health) to 0 (dead). QALYs can be used to inform health insurance coverage determinations, treatment decisions, to evaluate programs, and to set priorities for future programs. Critics argue that the QALY oversimplifies how actual patients would assess risks and outcomes, and that its use may restrict patients with disabilities from accessing treatment. Proponents of the measure acknowledge that the QALY has some shortcomings, but that its ability to quantify tradeoffs and opportunity costs from the patient and societal perspective make it a critical tool for equitably allocating resources. Calculation The QALY is a measure of the value of health outcomes to the people who experience t ...
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QALY Graph-en
The quality-adjusted life year (QALY) is a generic measure of disease burden, including both the quality and the quantity of life lived. It is used in economic evaluation to assess the value of medical interventions. One QALY equates to one year in perfect health. QALY scores range from 1 (perfect health) to 0 (dead). QALYs can be used to inform health insurance coverage determinations, treatment decisions, to evaluate programs, and to set priorities for future programs. Critics argue that the QALY oversimplifies how actual patients would assess risks and outcomes, and that its use may restrict patients with disabilities from accessing treatment. Proponents of the measure acknowledge that the QALY has some shortcomings, but that its ability to quantify tradeoffs and opportunity costs from the patient and societal perspective make it a critical tool for equitably allocating resources. Calculation The QALY is a measure of the value of health outcomes to the people who experience ...
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EQ-5D
EQ-5D is a standardised measure of health-related quality of life developed by thEuroQol Groupto provide a simple, generic questionnaire for use in clinical and economic appraisal and population health surveys. EQ-5D assesses health status in terms of five dimensions of health and is considered a ‘generic’ questionnaire because these dimensions are not specific to any one patient group or health condition. EQ-5D can also be referred to as a patient-reported outcome (PRO) measure, because patients can complete the questionnaire themselves to provide information about their current health status and how this changes over time. ‘EQ-5D’ is not an abbreviation and is the correct term to use when referring to the instrument in general. EQ-5D is widely used around the world in clinical trials and real-world clinical settings, population studies, and health economic evaluations. By mid-2020, the number of EQ-5D studies registered with the EuroQol Group totalled over 39,000. These co ...
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Incremental Cost-effectiveness Ratio
The incremental cost-effectiveness ratio (ICER) is a statistic used in cost-effectiveness analysis to summarise the cost-effectiveness of a health care intervention. It is defined by the difference in cost between two possible interventions, divided by the difference in their effect. It represents the average incremental cost associated with 1 additional unit of the measure of effect. The ICER can be estimated as: :ICER=\frac, where C_ and E_ are the cost and effect in the intervention group and where C_ and E_ are the cost and effect in the control care group. Costs are usually described in monetary units, while effects can be measured in terms of health status or another outcome of interest. A common application of the ICER is in cost-utility analysis, in which case the ICER is synonymous with the cost per quality-adjusted life year (QALY) gained. Use as a decision rule The ICER can be used as a decision rule in resource allocation. If a decision-maker is able to establish a ...
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Incremental Cost-effectiveness Ratio
The incremental cost-effectiveness ratio (ICER) is a statistic used in cost-effectiveness analysis to summarise the cost-effectiveness of a health care intervention. It is defined by the difference in cost between two possible interventions, divided by the difference in their effect. It represents the average incremental cost associated with 1 additional unit of the measure of effect. The ICER can be estimated as: :ICER=\frac, where C_ and E_ are the cost and effect in the intervention group and where C_ and E_ are the cost and effect in the control care group. Costs are usually described in monetary units, while effects can be measured in terms of health status or another outcome of interest. A common application of the ICER is in cost-utility analysis, in which case the ICER is synonymous with the cost per quality-adjusted life year (QALY) gained. Use as a decision rule The ICER can be used as a decision rule in resource allocation. If a decision-maker is able to establish a ...
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Time-trade-off
In health economics, time trade-off (TTO) is a technique used to measure the quality of life that a person or group is experiencing. An individual will be presented with a set of directions such as: Imagine that you are told that you have 10 years left to live. In connection with this you are also told that you can choose to live these 10 years in your current health state or that you can choose to give up some life years to live for a shorter period in full health. Indicate with a cross on the line the number of years in full health that you think is of equal value to 10 years in your current health state. The answer given by the individual shows how many years in the current health state they would be willing to 'trade off', in order to regain full health. This answer can be used to calculate the individual's quality of life in that health state. For example, an individual with severe asthma could be offered 10 years in their current condition, or a shorter length of time in ful ...
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Disease Burden
Disease burden is the impact of a health problem as measured by financial cost, mortality, morbidity, or other indicators. It is often quantified in terms of quality-adjusted life years (QALYs) or disability-adjusted life years (DALYs). Both of these metrics quantify the number of years lost due to disability (YLDs), sometimes also known as years lost due to disease or years lived with disability/disease. One DALY can be thought of as one year of healthy life lost, and the overall disease burden can be thought of as a measure of the gap between current health status and the ideal health status (where the individual lives to old age without disease and disability). According to an article published in ''The Lancet'' in June 2015, low back pain and major depressive disorder were among the top ten causes of YLDs and were the cause of more health loss than diabetes, chronic obstructive pulmonary disease, and asthma combined. The study based on data from 188 countries, considered ...
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Ariel Beresniak
Ariel Beresniak (born 3 December 1961) is a Swiss specialist in Public Health and Health Economics, author of reference books and scientific articles in modeling and decision-making analyses. Biography Beresniak is a physician specialized in Public Health from the Faculty of Medicine at University of Marseille, France . He also obtained a master's degree in Economics and a PhD in applied mathematics in Economics at the Claude-Bernard University (France), and an Accreditation to Supervise Research (Habilitation a Diriger des Recherches). Beresniak was Chief Medical Officer of Epidemic Surveillance in Gabon in 1989 before contributing to implement medico-economic methodologies in the pharmaceutical industry for assessing the value of innovative treatments. He was Head of Health Economics for Glaxo-Wellcome (1993-1999) and Global Head of Pharmacoeconomics for Serono International (1999-2004). Since 2005, Beresniak is CEO oData Mining International He has been short-term consultant ...
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Scottish Medicines Consortium
Healthcare Improvement Scotland (HIS) is the national healthcare improvement organisation for Scotland. It is a public body which is part of the Scottish National Health Service, created in April 2011. History NHS Quality Improvement Scotland (NHS QIS) was established on 1 January 2003 as a special health board with a remit to improve the quality of healthcare in Scotland. Healthcare Improvement Scotland (HIS) was established by the Public Services Reform (Scotland) Act 2010, taking over the work of QIS and the regulatory functions, in regard to independent healthcare provision, previously conducted by the Care Commission, now renamed the Care Inspectorate. The first chair of HIS, serving from 2010 to 2018, was Dame Denise Coia. The function of this body is to implement the healthcare priorities of the Scottish Government, in particular the Healthcare Quality Strategy of NHS Scotland. Units Healthcare Improvement Scotland incorporates several organisations: * Healthcare Env ...
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Office Of Technology Assessment
The Office of Technology Assessment (OTA) was an office of the United States Congress that operated from 1974 to 1995. OTA's purpose was to provide congressional members and committees with objective and authoritative analysis of the complex scientific and technical issues of the late 20th century, i.e. technology assessment. It was a leader in practicing and encouraging delivery of public services in innovative and inexpensive ways, including early involvement in the distribution of government documents through electronic publishing. Its model was widely copied around the world. The OTA was authorized in 1972 and received its first funding in fiscal year 1974. It was defunded at the end of 1995, following the 1994 mid-term elections which led to Republican control of the Senate and the House. House Republican legislators characterized the OTA as wasteful and hostile to GOP interests. Princeton University hosts The OTA Legacy site, which holds "the complete collection of OTA publ ...
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Organisation For Economic Co-operation And Development
The Organisation for Economic Co-operation and Development (OECD; french: Organisation de coopération et de développement économiques, ''OCDE'') is an intergovernmental organisation with 38 member countries, founded in 1961 to stimulate economic progress and world trade. It is a forum whose member countries describe themselves as committed to democracy and the market economy, providing a platform to compare policy experiences, seek answers to common problems, identify good practices, and coordinate domestic and international policies of its members. The majority of OECD members are high-income economies with a very high Human Development Index (HDI), and are regarded as developed countries. Their collective population is 1.38 billion. , the OECD member countries collectively comprised 62.2% of global nominal GDP (US$49.6 trillion) and 42.8% of global GDP ( Int$54.2 trillion) at purchasing power parity. The OECD is an official United Nations observer. In April 1948 ...
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European Commission
The European Commission (EC) is the executive of the European Union (EU). It operates as a cabinet government, with 27 members of the Commission (informally known as "Commissioners") headed by a President. It includes an administrative body of about 32,000 European civil servants. The Commission is divided into departments known as Directorates-General (DGs) that can be likened to departments or ministries each headed by a Director-General who is responsible to a Commissioner. There is one member per member state, but members are bound by their oath of office to represent the general interest of the EU as a whole rather than their home state. The Commission President (currently Ursula von der Leyen) is proposed by the European Council (the 27 heads of state/governments) and elected by the European Parliament. The Council of the European Union then nominates the other members of the Commission in agreement with the nominated President, and the 27 members as a team are t ...
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Graham Loomes
Graham Loomes, (born 5 August 1950) is a British economist and academic, specialising in behavioural economics. Since 2009, he has been Professor of Economics and Behavioural Science at the University of Warwick. He previously worked at the University of Newcastle, the University of York and the University of East Anglia. Early life and education Loomes was born on 5 August 1950 to Frederick and Gladys Loomes. He was educated at Christ's Hospital, an independent school in Horsham, West Sussex, and at Westminster City School, then an all-boys grammar school in Westminster, London. He studied economics at the University of Essex, and graduated with a Bachelor of Arts (BA) degree in 1970. After a period as a teacher, he undertook postgraduate studies in economics at Birkbeck College, University of London and graduated with a Master of Science (MSc) degree in 1978. Academic career Loomes began his academic career as a teacher rather than a lecturer. Having graduated from univ ...
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